Browsing Faculty of Medicine by Title
Now showing items 608-627 of 8760
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Autoantigenic properties of the aminoacyl tRNA synthetase family in idiopathic inflammatory myopathies
(Journal article; Peer reviewed, 2023)Objectives: Autoantibodies are thought to play a key role in the pathogenesis of idiopathic inflammatory myopathies (IIM). However, up to 40% of IIM patients, even those with clinical manifestations of anti-synthetase ... -
Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells
(Journal article; Peer reviewed, 2023)The emergence of castration-resistant prostate cancer remains an area of unmet clinical need. We recently identified a subpopulation of normal prostate progenitor cells, characterized by an intrinsic resistance to androgen ... -
Autoimmune Addison's Disease and DNA Methylation. Identification of Differentially Methylated Regions and Development of Methylation Specific PCR for Selected Genes
(Master thesis, 2012-07-01)Autoimmune Addison's Disease (AAD) is a classical organ-specific autoimmune disease (AID) that is characterized by autoreactivity towards the adrenal cortex, leading to insufficient production of steroid hormones and death ... -
Autoimmune polyendocrine syndrome type I. Novel diagnostic assays and immune regulation
(Doctoral thesis, 2012-02-10)Autoimmune polyendocrine syndrome type I (APS-I) is a rare, monogenetic recessively inherited disease caused by mutations in the autoimmune regulator (AIRE) gene. The patients display different endocrine and ectodermal ... -
Autoimmune primary adrenal insufficiency – autoantibodies and cell regeneration
(Doctoral thesis, 2024-02-02)Autoimmun primær binyrebarksvikt er en sjelden lidelse som skyldes autoimmun ødeleggelse av binyrebarken, og foreløpig finnes det ingen kurativ behandling. Her undersøkte vi to distinkte aspekter ved sykdommen, en molekylær ... -
Autoimmune Thyroid Disorders in Autoimmune Addison Disease
(Journal article; Peer reviewed, 2022)Context: Autoimmune thyroid disease is the most common endocrine co-morbidity in autoimmune Addison's disease (AAD), but detailed investigations of prevalence and clinical course is lacking. Objective: Provide comprehensive ... -
Autoimmunity and viral immunity in Addison’s disease
(Doctoral thesis, 2015-11-27)Autoimmune Addison’s disease (AAD) is caused by an immunological destruction of the steroid producing cells of the adrenal cortex. Both genetic and environmental factors are involved in disease development, and while ... -
Autologous stem cells as a promising therapeutic approach for augmentation of alveolar bone
(Doctoral thesis, 2020-08-28)The current gold standard for reconstructive bone surgery is based on autologous bone grafts. However, the risk of complications at both the donor and recipient sites is considerable. There is therefore a need to explore ... -
Automated Quantification and Integrative Analysis of 2D and 3D Mitochondrial Shape and Network Properties
(Peer reviewed; Journal article, 2014-07-02)Mitochondrial morphology and function are coupled in healthy cells, during pathological conditions and (adaptation to) endogenous and exogenous stress. In this sense mitochondrial shape can range from small globular ... -
Automated segmentation of endometrial cancer on MR images using deep learning
(Journal article; Peer reviewed, 2021)Preoperative MR imaging in endometrial cancer patients provides valuable information on local tumor extent, which routinely guides choice of surgical procedure and adjuvant therapy. Furthermore, whole-volume tumor analyses ... -
Automated spectrophotometric bicarbonate analysis in duodenal juice compared to the back titration method
(Peer reviewed; Journal article, 2016-02-03)Objectives We have recently evaluated a short endoscopic secretin test for exocrine pancreatic function. Bicarbonate concentration in duodenal juice is an important parameter in this test. Measurement of bicarbonate by ... -
Automated splitting into batches for observational biomedical studies with sequential processing
(Journal article; Peer reviewed, 2022)Experimental design usually focuses on the setting where treatments and/or other aspects of interest can be manipulated. However, in observational biomedical studies with sequential processing, the set of available samples ... -
Automatic Estimation of Coronary Blood Flow Velocity Step 1 for Developing a Tool to Diagnose Patients With Micro-Vascular Angina Pectoris
(Peer reviewed; Journal article, 2019-01-22)Aim: Our aim was to automatically estimate the blood velocity in coronary arteries using cine X-ray angiographic sequence. Estimating the coronary blood velocity is a key approach in investigating patients with angina ... -
Autonomy conquers all: a thematic analysis of nurses’ professional judgement encountering resistance to care from home-dwelling persons with dementia
(Journal article; Peer reviewed, 2022)Background Adequate care support from home health care nurses is needed to meet the needs of an increasing number of home-dwelling persons with dementia and those who resist care. The decisions nurses make in home health ... -
The autonomy of different aspects of Sjögren´s syndrome and their treatment in an experimental model: the use of comprehensive biomarker analyses to characterize the disease and the effect of heat-shock proteins in treatment intervention
(Doctoral thesis, 2008-06-20)Sjögren’s syndrome (SS) is a systemic rheumatic disease, in which the salivary and lacrimal glands are the principal targets of a pathological autoimmune reaction. Clinically, SS is manifested by keratoconjunctivitis sicca ... -
Autotaxin activity predicts transplant-free survival in primary sclerosing cholangitis
(Peer reviewed; Journal article, 2019-06-11)Autotaxin has been associated with liver disease severity and transplant-free survival. This study aimed to validate autotaxin as a biomarker in two cohorts of Norwegian large-duct PSC patients, one discovery panel (n=165) ... -
Autotransplantasjon og kjeveortopedisk behandling - en undersøkelse av behandlingsresultater ved Odontologisk Universitetsklinikk
(Master thesis, 2012-01-26)Mål: Å etterundersøke pasienter med agenesi eller tanntap som følge av traume som hadde fått utført autotransplantasjon av premolarer før kjeveortopedisk behandling. Material og metode: Fra 1979 til 2012 ble 17 premolarer ... -
Autotransplantasjoner - en retrospektiv studie av 75 transplanterte tenner
(Master thesis, 2012-01-25)Denne retrospektive studien rapporterer og evaluerer 75 autotransplantasjoner utført i perioden juni 2001 - september 2011 ved Seksjon for Oral Kirurgi og Oral Medisin ved Odontologisk Universitetsklinikk, UiB. Alle ... -
Autozygosity mapping and time-to-spontaneous delivery in Norwegian parent-offspring trios
(Journal article; Peer reviewed, 2020)Parental genetic relatedness may lead to adverse health and fitness outcomes in the offspring. However, the degree to which it affects human delivery timing is unknown. We use genotype data from ≃25 000 parent-offspring ... -
Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function
(Journal article; Peer reviewed, 2022)Objective: Neonatal lupus erythematosus (NLE) may develop after transplacental transfer of maternal autoantibodies with cardiac manifestations (congenital heart block, CHB) including atrioventricular block, atrial and ...