Blar i Faculty of Medicine på forfatter "Hatlebakk, Jan Gunnar"
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The kinetics of gut microbial community composition in patients with irritable bowel syndrome following fecal microbiota transplantation
Mazzawi, Tarek; Lied, Gülen Arslan; Sangnes, Dag André; El-Salhy, Magdy; Hov, Johannes Espolin Roksund; Gilja, Odd Helge; Hatlebakk, Jan Gunnar; Hausken, Trygve (Peer reviewed; Journal article, 2018-11-14)Background: Gut microbiota alterations are important in irritable bowel syndrome (IBS). The aim was to investigate the effect of fecal microbiota transplantation (FMT) on gut microbiota and the symptoms in patients with ... -
Long-term effects of fecal microbiota transplantation (FMT) in patients with irritable bowel syndrome
El-Salhy, Magdy; Bråthen Kristoffersen, Anja; Valeur, Jørgen; Casén, Christina; Hatlebakk, Jan Gunnar; Gilja, Odd Helge; Hausken, Trygve (Journal article; Peer reviewed, 2021)Background We recently found fecal microbiota transplantation (FMT) in irritable bowel syndrome (IBS) patients to be an effective and safe treatment after 3 months. The present follow-up study investigated the efficacy ... -
Low Densities of Serotonin and Peptide YY Cells in the Colon of Patients with Irritable Bowel Syndrome
El-Salhy, Magdy; Gundersen, Doris; Østgaard, Hege; Lomholt-Beck, B.; Hatlebakk, Jan Gunnar; Hausken, Trygve (Peer reviewed; Journal article, 2011-11-05)Background The gut hormones are important in regulating gastrointestinal motility. Disturbances in gastrointestinal motility have been reported in patients with irritable bowel syndrome (IBS). Reduced endocrine cell density, ... -
Navigated retrograde endoscopic myotomy (REM) for the treatment of therapy-resistant achalasia
Pham, Khanh Do-Cong; Havre, Roald Flesland; Langø, Thomas; Hofstad, Erlend Fagertun; Tangen, Geir Arne; Mårvik, Ronald; Pham, T.; Gilja, Odd Helge; Hatlebakk, Jan Gunnar; Viste, Asgaut (Peer reviewed; Journal article, 2018-04)Background In achalasia, muscle spasm may involve the proximal esophagus. When the muscle spasm is located in the proximal esophagus, conventional per oral endoscopic myotomy (POEM) may not be sufficient to relieve symptoms. ... -
The outcome of primary per oral endoscopic myotomy (POEM) for treatment of achalasia: Norwegian single-center experience with long-term follow-up
Pham, Khanh Do-Cong; Lauritzen, Sigurd; Tjora, Erling; Gilja, Odd Helge; Hatlebakk, Jan Gunnar; Assmus, Jörg; Havre, Roald Flesland (Journal article; Peer reviewed, 2022)Background and aims: Per oral endoscopic myotomy (POEM) has become an established treatment for achalasia, but no Scandinavian studies with long-term follow-up exist. This study from a tertiary referral center in Norway ... -
Overlapping of irritable bowel syndrome with erosive esophagitis and the performance of Rome criteria in diagnosing IBS in a clinical setting
El-Salhy, Magdy; Gilja, Odd Helge; Hatlebakk, Jan Gunnar (Peer reviewed; Journal article, 2019)Irritable bowel syndrome (IBS) and gastroesophageal reflux disease (GERD) overlap. It is not clear whether GERD is caused by non‑erosive esophagitis, or erosive esophagitis. The Rome criteria are not widely used for the ... -
Pathophysiology of idiopathic gastroparesis and implications for therapy
Bekkelund, Mattis; Sangnes, Dag André; Hatlebakk, Jan Gunnar; Aabakken, Lars (Peer reviewed; Journal article, 2019)Objectives: Idiopathic gastroparesis is a gastric motility disorder characterized by chronic upper gastrointestinal symptoms and delayed gastric emptying without an identifiable underlying condition. This review summarizes ... -
Possible role of peptide YY (PYY) in the pathophysiology of irritable bowel syndrome (IBS)
El-Salhy, Magdy; Hatlebakk, Jan Gunnar; Hausken, Trygve (Peer reviewed; Journal article, 2020)Irritable bowel syndrome (IBS) is a common gastrointestinal disorder of unknown aetiology for which there is no effective treatment. Although IBS does not increase mortality, it reduces the quality of life and is an economic ... -
The relation between celiac disease, nonceliac gluten sensitivity and irritable bowel syndrome
El-Salhy, Magdy; Hatlebakk, Jan Gunnar; Gilja, Odd Helge; Hausken, Trygve (Peer reviewed; Journal article, 2015-09-07)Wheat products make a substantial contribution to the dietary intake of many people worldwide. Despite the many beneficial aspects of consuming wheat products, it is also responsible for several diseases such as celiac ... -
Responses to faecal microbiota transplantation in female and male patients with irritable bowel syndrome
El-Salhy, Magdy; Casén, Christina; Valeur, Jørgen; Hausken, Trygve; Hatlebakk, Jan Gunnar (Journal article; Peer reviewed, 2021-05-14)BACKGROUND Faecal microbiota transplantation (FMT) seems to be a promising treatment for irritable bowel syndrome (IBS) patients. In Western countries (United States and Europe), there is a female predominance in IBS. A ... -
Study protocol of the Bergen brain-gut-microbiota-axis study: A prospective case-report characterization and dietary intervention study to evaluate the effects of microbiota alterations on cognition and anatomical and functional brain connectivity in patients with irritable bowel syndrome
Berentsen, Birgitte; Nagaraja, Bharath Halandur; Teige, Erica Persson; Lied, Gülen Arslan; Lundervold, Astri; Lundervold, Katarina; Steinsvik, Elisabeth Kjelsvik; Hillestad, Eline Margrete Randulff; Valeur, Jørgen; Brønstad, Ingeborg; Gilja, Odd Helge; Osnes, Berge; Hatlebakk, Jan Gunnar; Haász, Judit; Labus, Jennifer; Gupta, Arpana; Mayer, Emeran; Benitez-Páez, Alfonso; Sanz, Yolanda; Lundervold, Arvid; Hausken, Trygve (Journal article; Peer reviewed, 2020-09)Introduction: Irritable bowel syndrome (IBS) is a common clinical label for medically unexplained gastrointestinal (GI) symptoms, recently described as a disturbance of the brain-gut-microbiota (BGM) axis. To gain a ... -
Supplementation with cod protein hydrolysate in older adults: A dose range cross-over study
Jensen, Caroline; Dale, Hanna Fjeldheim; Hausken, Trygve; Lied, Einar; Hatlebakk, Jan Gunnar; Brønstad, Ingeborg; Lied, Gülen Arslan; Hoff, Dag Arne Lihaug (Peer reviewed; Journal article, 2019)A large proportion of older adults are affected by impaired glucose metabolism. Previous studies with fish protein have reported improved glucose regulation in healthy adults, but the evidence in older adults is limited. ... -
Supplementation with Low Doses of a Cod Protein Hydrolysate on Glucose Regulation and Lipid Metabolism in Adults with Metabolic Syndrome: A Randomized, Double-Blind Study
Jensen, Caroline; Dale, Hanna Fjeldheim; Hausken, Trygve; Hatlebakk, Jan Gunnar; Brønstad, Ingeborg; Lied, Gülen Arslan; Hoff, Dag Arne Lihaug (Journal article; Peer reviewed, 2020)The risk of cardiovascular diseases and type 2 diabetes mellitus are increased in subjects with metabolic syndrome (MetS), and hydrolyzed fish protein may have favorable effects on metabolic health. Here, we investigated ... -
Ultrasound imaging for assessing functions of the GI tract
Steinsvik, Elisabeth Kjelsvik; Hatlebakk, Jan Gunnar; Hausken, Trygve; Nylund, Kim; Gilja, Odd Helge (Journal article; Peer reviewed, 2021)Objective: In the following review we outline how ultrasound can be used to measure physiological processes in the gastrointestinal tract. Approach: We have investigated the potential of ultrasound in assessing ...