Blar i Faculty of Medicine på tittel

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    • The role of Gastro Esophageal Reflux in Chronic Rhinosinusitis 

      Katle, Elin-Johanne (Doctoral thesis, 2019-06-20)
      Background: Chronic Rhino Sinusitis (CRS) is one of the most prevalent chronic disorders in industrialized countries. The disease has a major negative impact on quality of life, social and professional capacity as well as ...

    • The role of general practitioners in the pre hospital setting, as experienced by emergency medicine technicians: a qualitative study 

      Hjortdahl, Magnus; Zakariassen, Erik; Wisborg, Torben (Peer reviewed; Journal article, 2014-08-22)
      Background: Together with the ambulances staffed with emergency medical technicians (EMTs), general practitioners (GPs) on call are the primary resources for handling emergencies outside hospitals in Norway. The benefit ...

    • Role of gingival lymphatics in tissue fluid balance and periodontal disease development 

      Mkonyi, Lilian E. (Doctoral thesis, 2012-05-25)
      Background: The gingiva is frequently challenged to oral bacteria which are able to induce inflammatory responses with increased fluid filtration and edema formation in the tissue. Under given circumstances periodontal ...

    • The role of imaging in anterior cruciate ligament reconstruction 

      Parkar, Anagha P. (Doctoral thesis, 2021-08-27)
      The thesis is based on four articles examining the role of imaging after surgical reconstruction of the anterior cruciate ligament of the knee. Post-operative imaging is commonly performed to validate ACL graft tunnel ...

    • The role of inflammation in anxiety and depression in the European U-BIOPRED asthma cohorts 

      Hou, Ruihua; Ye, Gang; Cheng, Xiaojing; Shaw, Dominick E.; Bakke, Per S.; Caruso, Massimo; Dahlen, Barbro; Dahlen, Sven-Erik; Fowler, Stephen J.; Horváth, Ildikó; Howarth, Peter; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Auffray, Charles; De Meulder, Bertrand; Sousa, Ana R.; Adcock, Ian M.; Fan Chung, Kian; Sterk, Peter J.; Skipp, Paul J.; Schofield, James; Djukanović, Ratko (Journal article; Peer reviewed, 2023)
      Background: Growing evidence indicates high comorbid anxiety and depression in patients with asthma. However, the mechanisms underlying this comorbid condition remain unclear. The aim of this study was to investigate the ...

    • Role of integrin α11 in oral carcinogenesis. In vitro and in vivo studies 

      Parajuli, Himalaya (Doctoral thesis, 2016-04-29)
      Cancer research has provided evidence for several advanced and better ways of treatment, helping the community for a better living. Nevertheless, for head and neck cancer there is still a long way to go for achieving an ...

    • Role of integrin α11β1 in breast cancer 

      Smeland, Hilde Ytre-Hauge (Doctoral thesis, 2021-09-24)
      Breast cancer cells are strongly influenced by a complex tumor microenvironment comprised of a diversity of stromal cells, including a heterogeneous population of cancer associated fibroblasts (CAFs), in addition to the ...

    • The role of interleukin-6 classical and trans-signaling in allogeneic stem cell transplantation 

      Tvedt, Tor Henrik Anderson (Doctoral thesis, 2020-04-02)
      IL-6 family cytokines share structural similarities and utilize glycoprotein 130 (gp130) for signal transduction. IL-6 itself has both pro- and anti-inflammatory effects. IL-6 trans-signaling is mediated by the soluble ...

    • The role of livestock keeping in tuberculosis trends in Arusha, Tanzania 

      Mfinanga, Sayoki Godfrey; Mørkve, Odd; Kazwala, R. R.; Cleaveland, S.; Sharp, J. M.; Shirima, G.; Nilsen, Rune (Peer reviewed; Journal article, 2003-07)
      SETTING: Arusha, Tanzania. OBJECTIVE: To assess risk factors that might influence TB control in the general population and in livestock-keepers. METHODS: Of 242 villages in four districts, 27 were selected randomly. In ...

    • The Role of Long-Chained Marine N-3 Polyunsaturated Fatty Acids in Cardiovascular Disease 

      Aarsetøy, Hildegunn; Grundt, Heidi; Nygård, Ottar; Nilsen, Dennis W.T. (Peer reviewed; Journal article, 2012)
      This paper reviews the current evidence regarding long-chained marine omega-3 polyunsaturated fatty acids (PUFAs) and cardiovascular disease (CVD), their possible mechanisms of action, and results of clinical trials. Also, ...

    • Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study 

      Magnus, Maria Christine; Wilcox, Allen J; Morken, Nils-Halvdan; Weinberg, Clarice R.; Håberg, Siri Eldevik (Peer reviewed; Journal article, 2019)
      Objectives: To estimate the burden of miscarriage in the Norwegian population and to evaluate the associations with maternal age and pregnancy history. Design: Prospective register based study. Setting: Medical Birth ...

    • The Role of Mental Health and Behavioral Disorders in the Development of Temporomandibular Disorder: A SWEREG-TMD Nationwide Case-Control Study 

      Fredricson, Adrian Salinas; Weiner, Carina Krüger; Adami, Johanna; Rosén, Annika; Lund, Bodil Kristina; Hedenberg-Magnusson, Britt; Fredriksson, Lars; Naimi-Akbar, Aron (Journal article; Peer reviewed, 2022)
      Purpose: There is a well-known association between mental and behavioral disorders (MBD) and temporomandibular disorder (TMD), although the association has not been established in population-based samples. This study aimed ...

    • The role of microRNAs as predictors of response to tamoxifen treatment in breast cancer patients 

      Egeland, Nina; Lunde, Siri; Jonsdottir, Kristin; Lende, Tone Hoel; Cronin-Fenton, Deirdre P.; Gilje, Bjørnar; Janssen, Emilius Adrianus Maria; Søiland, Håvard (Peer reviewed; Journal article, 2015-10-14)
      Endocrine therapy is a key treatment strategy to control or eradicate hormone-responsive breast cancer. However, resistance to endocrine therapy leads to breast cancer relapse. The recent extension of adjuvant tamoxifen ...

    • The role of NF-κB transcription factor in cellular response to ionizing radiation 

      Janus, Patryk; Szoltysek, Katarzyna; Zajac, Gracjana; Widlak, Wieslawa; Stokowy, Tomasz; Wojtas, Bartosz; Widlak, Piotr (Journal article, 2019)
      The NF-κB transcription factor is involved in different aspects of the cellular response to stress, including atypical NF-κB pathway activated by damage induced by ionizing radiation. Moreover, NF-κB could be involved in ...

    • Role of parents in adolescent self-rated health: Norwegian Nord-Trøndelag Health Study 

      Breidablik, Hans-Johan; Meland, Eivind; Holmen, Turid Lingaas; Lydersen, Stian (Peer reviewed; Journal article, 2010-09)
      Background: Self-rated health (SRH) is a known important predictor of later mortality, morbidity, and health service attendance. From adolescence onwards, this multifactorial composite seems to be relatively stable. ...

    • Role of pitrm1 in mitochondrial dysfunction and neurodegeneration 

      Brunetti, Dario; Catania, Alessia; Viscomi, Carlo; Deleidi, Michela; Bindoff, Laurence Albert; Ghezzi, Daniele; Zeviani, Massimo (Journal article; Peer reviewed, 2021)
      Mounting evidence shows a link between mitochondrial dysfunction and neurodegenerative disorders, including Alzheimer Disease. Increased oxidative stress, defective mitodynamics, and impaired oxidative phosphorylation ...

    • The role of Polish school nurses in the oral health promotion for 7-19 year-old children and adolescents 

      Baginska, Joanna; Rodakowska, Ewa Joanna; Kobus, Agnieszka; Kierklo, Anna (Journal article; Peer reviewed, 2021)
      Purpose The assessment of the role of school nurses in the oral health education and counselling of children and adolescents aged 7–19 years. Methods A self-administered questionnaire was used to evaluate nurses’ ...

    • The role of pregnancy in maternal cancer risk: Epidemiologic evidence from the Nordic Countries Linked Birth and Cancer Registries Cohort Project 

      Troisi, Rebecca; Glimelius, Ingrid; Grotmol, Tom; Gissler, Mika; Kitahara, Cari M.; Ording, Anne Gulbech; Sæther, Solbjørg Makalani Myrtveit; Sköld, Camilla; Sørensen, Henrik Toft; Trabert, Britton; Bjørge, Tone (Journal article; Peer reviewed, 2022)
      The experience of pregnancy has a lasting impact, in many cases beneficial, on cancer risk in the mother. In the long term, breast, ovarian, and endometrial cancers are lower in parous women, and each pregnancy provides ...

    • The Role of Psychological Readiness in Return to Sport Assessment After Anterior Cruciate Ligament Reconstruction 

      Faleide, Anne Gro Heyn; Magnussen, Liv Heide; Strand, Torbjørn; Bogen, Bård Erik; Moe-Nilssen, Rolf; Mo, Ingunn Fleten; Vervaat, Willemijn; Inderhaug, Eivind (Journal article; Peer reviewed, 2021)
      Background: Knowledge about the predictive value of return to sport (RTS) test batteries applied after anterior cruciate ligament reconstruction (ACLR) is limited. Adding assessment of psychological readiness has been ...

    • The role of PTEN, PI3K-Akt-mTOR signaling and pseudogene PTENP1 in breast cancer 

      Yndestad, Synnøve (Doctoral thesis, 2018-04-19)
      Background: Breast cancer is the most common type of cancer in women, and a major cause of premature death still today. The PI3K-Akt-mTOR signaling (in short: PI3K signaling) pathway is a growth and pro-survival pathway, ...