Blar i Faculty of Medicine på forfatter "Harris, Gerd Marie Eskerud"
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Identification of pharmacological chaperones for Phenylalanine Hydroxylase. A virtual screening approach to discover novel drug candidates for treatment of phenylketonuria
Harris, Gerd Marie Eskerud (Master thesis, 2014-05-20)Phenylalanine hydroxylase (PAH) is an enzyme that catalyses the hydroxylation of phenylalanine into tyrosine in the liver, which is the rate-limiting step in phenylalanine catabolism. PAH is a non-heme iron-dependent enzyme ...