Blar i Bergen Open Research Archive på tittel

Viser treff 15542-15561 av 34096

    • Inhibition of extracellular vesicle-derived miR-146a-5p decreases progression of melanoma brain metastasis via Notch pathway dysregulation in astrocytes 

      Rigg, Emma Kayleigh; Wang, Jiwei; Xue, Zhiwei; Lunavat, Taral; Liu, Guowei; Hoang, Tuyen; Parajuli, Himalaya; Han, Mingzhi; Bjerkvig, Rolf; Nazarov, Petr V.; Nicot, Nathalie; Kreis, Stephanie; Margue, Christiane; Nomigni, Miléne Tetsi; Utikal, Jochen; Miletic, Hrvoje; Sundstrøm, Terje; Ystaas, Lars Andreas Rømo; Li, Xingang; Thorsen, Frits (Journal article; Peer reviewed, 2023)
      Melanoma has the highest propensity of all cancers to metastasize to the brain with a large percentage of late-stage patients developing metastases in the central nervous system (CNS). It is well known that metastasis ...

    • Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis 

      Sundstrøm, Terje; Prestegarden, Lars; Azuaje, Francisco; Aasen, Synnøve Nymark; Røsland, Gro Vatne; Varughese, Jobin K.; Bahador, Marzieh; Bernatz, Simon; Braun, Yannick; Harter, Patrick N.; Skaftnesmo, Kai Ove; Ingham, Elizabeth S.; Mahakian, Lisa M.; Tam, Sarah; Tepper, Clifford G.; Petersen, Kjell; Ferrara, Katherine W.; Tronstad, Karl Johan; Lund-Johansen, Morten; Beschorner, Rudi; Bjerkvig, Rolf; Thorsen, Frits (Peer reviewed; Journal article, 2019-04-10)
      Melanoma patients carry a high risk of developing brain metastases, and improvements in survival are still measured in weeks or months. Durable disease control within the brain is impeded by poor drug penetration across ...

    • Inhibition of NF-κB signaling alters acute myelogenous leukemia cell transcriptomics 

      Reikvam, Håkon (Journal article; Peer reviewed, 2020)
      Acute myelogenous leukemia (AML) is an aggressive hematological malignancy. The pathophysiology of the disease depends on cytogenetic abnormalities, gene mutations, aberrant gene expressions, and altered epigenetic regulation. ...

    • Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach 

      Dublang, Leire; Underhaug, Jarl; Flydal, Marte Innselset; Velasco-Carneros, Lorea; Maréchal, Jean-Didier; Moro, Fernando; Boyano, Maria Dolores; Martinez, Aurora; Muga, Arturo (Journal article; Peer reviewed, 2021)
      Heat shock protein (Hsp) synthesis is upregulated in a wide range of cancers to provide the appropriate environment for tumor progression. The Hsp110 and Hsp70 families have been associated to cancer cell survival and ...

    • Inhibition of Tryptophan Hydroxylases and Monoamine Oxidase-A by the Proton Pump Inhibitor, Omeprazole—In Vitro and In Vivo Investigations 

      Betari, Nibal; Sahlholm, Kristoffer; Morató, Xavier; Godoy-Marín, Héctor; Jáuregui, Olga; Teigen, Knut; Ciruela, Francisco; Haavik, Jan (Journal article; Peer reviewed, 2020)
      Serotonin (5-HT) is a hormone and neurotransmitter that modulates neural activity as well as a wide range of other physiological processes including cardiovascular function, bowel motility, and platelet aggregation. 5-HT ...

    • Inhibition of tunneling nanotube (TNT) formation and Human T-cell leukemia virus type 1 (HTLV-1) transmission by cytarabine 

      Omsland, Maria; Pise-Masison, Cynthia A.; Fujikawa, Dai; Galli, Veronica; Fenizia, Claudio; Parks, Robyn Washington; Gjertsen, Bjørn Tore; Franchini, Genoveffa; Andresen, Vibeke (Peer reviewed; Journal article, 2018-07-24)
      The human T-cell leukemia virus type 1 (HTLV-1) is highly dependent on cell-to-cell interaction for transmission and productive infection. Cell-to-cell interactions through the virological synapse, bioflm-like structures ...

    • Inhibition of VMAT2 by β2-adrenergic agonists, antagonists, and the atypical antipsychotic ziprasidone 

      Støve, Svein Isungset; Skjevik, Åge Aleksander; Teigen, Knut; Martinez, Aurora (Journal article; Peer reviewed, 2022)
      Vesicular monoamine transporter 2 (VMAT2) is responsible for packing monoamine neurotransmitters into synaptic vesicles for storage and subsequent neurotransmission. VMAT2 inhibitors are approved for symptomatic treatment ...

    • Inhibitory control as possible risk and/or resilience factor for the development of trauma related symptoms–a study of the Utøya terror attack survivors 

      Hammar, Åsa Karin; Schmid, Marit Therese; Petersdotter, Linn; Ousdal, Olga Therese; Milde, Anne Marita (Journal article; Peer reviewed, 2023)
      PTSD symptomatology is known to be associated with executive dysfunction. Inhibitory control is a core component of executive functioning, and inhibitory skills are essential both for adequate functioning in everyday life ...

    • Inhibitory inputs to an inhibitory interneuron: Spontaneous postsynaptic currents and GABA_A receptors of A17 amacrine cells in the rat retina 

      Beltran Matas, Pablo; Castilho, Aurea; Tencer, Barbora; Veruki, Margaret Lin; Hartveit, Espen (Journal article; Peer reviewed, 2022)
      Amacrine cells constitute a large and heterogeneous group of inhibitory interneurons in the retina. The A17 amacrine plays an important role for visual signalling in the rod pathway microcircuit of the mammalian retina. ...

    • Initial (March 2023) uses and perceptions of ChatGPT in a sample of students and instructors at the University of Bergen (UiB), Norway 

      Møgelvang, Anja; Bjune, Anne E.; Coelho, Raquel; Cotner, Sehoya; Grellscheid, David; Ellingsen, Ståle (SLATE Research Report;2023-1, Research report, 2023-06)
      The spring semester of 2023 in higher education was impacted by the release of Large Language Models (LLMs) to the general public. OpenAI’s ChatGPT was at the forefront, with Google's Bard, Microsoft’s Bing, and others ...

    • An initial assessment of zooarchaeological assemblage sizes from South Africa 

      Badenhorst, Shaw; Mthombothi, Nomaswazi; Niekerk, Karen Loise van; Henshilwood, Christopher Stuart (Journal article, 2022)
      Large faunal assemblages remain a concern in zooarchaeology. Without sufficiently large assemblages, interpretations about the past are less secure. The number of potential taxa in an assemblage is related to various factors ...

    • Initial healthcare and coping preferences are associated with outcome 1 year after whiplash trauma: A multicentre 1-year follow-up study 

      Myrtveit, Solbjørg Makalani; Carstensen, Tina; Kasch, Helge; Ørnbøl, Eva; Frostholm, Lisbeth (Peer reviewed; Journal article, 2015-03-20)
      Objective: Individuals exposed to whiplash collisions have to cope with the stressful event as well as early physical symptoms. As in other chronic pain conditions, coping has been associated with outcome after whiplash. ...

    • Initial rhythm control with cryoballoon ablation vs drug therapy: Impact on quality of life and symptoms 

      Pavlovic, Nikola; Chierchia, Gian-Battista; Velagic, Vedran; Hermida, Jean Sylvain; Healey, Stewart; Arena, Giuseppe; Badenco, Nicolas; Meyer, Christian; Chen, Jian; Iacopino, Saverio; Anselme, Frédéric; Dekker, Lukas; Scazzuso, Fernando; Packer, Douglas L.; de Asmundis, Carlo; Pitschner, Heinz-Friedrich; Piazza, Fabio Di; Kaplon, Rachelle E.; Kuniss, Malte (Journal article; Peer reviewed, 2021)
      Background Cryoballoon ablation (CBA) as a first-line rhythm control strategy is superior to antiarrhythmic drugs (AADs) for preventing atrial fibrillation (AF) recurrence; the impact of first-line CBA on quality of life ...

    • Initialization shock in the ocean circulation reduces skill in decadal predictions of the North Atlantic subpolar gyre 

      Polkova, Iuliia; Swingedouw, Didier; Hermanson, Leon; Köhl, Armin; Stammer, Detlef; Smith, Doug; Kröger, Jürgen; Bethke, Ingo; Yang, Xiaosong; Zhang, Liping; Nicolì, Dario; Athanasiadis, Panos J.; Karami, Mehdi Pasha; Pankatz, Klaus; Pohlmann, Holger; Wu, Bo; Bilbao, Roberto; Ortega, Pablo; Yang, Shuting; Sospedra-Alfonso, Reinel; Merryfield, William; Kataoka, Takahito; Tatebe, Hiroaki; Imada, Yukiko; Ishii, Masayoshi; Matear, Richard J. (Journal article; Peer reviewed, 2023)
      Due to large northward heat transport, the Atlantic meridional overturning circulation (AMOC) strongly affects the climate of various regions. Its internal variability has been shown to be predictable decades ahead within ...

    • Initiation of anti-osteoporotic drugs in high-risk female patients starting glucocorticoid treatment: a population study in Norway 

      Apalset, Ellen Margrete; Lunde, Astrid; Hoff, Mari; Ehrenstein, Vera; Tell, Grethe S. (Journal article; Peer reviewed, 2020)
      Summary: Glucocorticoid use is a risk factor for osteoporosis and fractures. We studied whether women initiating glucocorticoid treatment also started anti-osteoporotic treatment, according to clinical guidelines. Women ...

    • Initiation of lightning flashes simultaneously observed from space and the ground: Narrow bipolar events 

      López, Jesús A.; Montanyà, Joan; van der Velde, Oscar; Romero, David; Gordillo-Vázquez, Francisco J.; Pérez-Invernón, Francisco J.; Luque, Alejandro; Morales Rodriguez, Carlos Augusto; Neubert, Torsten; Rison, William; Krehbiel, Paul; González, Javier Navarro; Østgaard, Nikolai; Reglero, Víctor (Journal article; Peer reviewed, 2022)
      We investigate the initiation of four lightning flashes detected from ground by means of the Colombia Lightning Mapping Array (Colombia-LMA) and simultaneously observed from space by the optical sensors of the Atmosphere-Space ...

    • Initiativ og respons i dialoger. En ny innfallsvinkel til analyse av andrespråkstilegnelse 

      Tenfjord, Kari (Journal article, 1991)
      I denne artikkelen vil jeg forsøke å vise at tverrfaglig kontakt kan gi nye ideer til modell- og teoriutvikling i andrespråks­forskningen. Jeg har hentet begrepene 'initiativ' og 'respons' fra dialoganalyse i barnespråks ...

    • Injectable In Situ Crosslinking Hydrogel for Autologous Fat Grafting 

      Oskarsdotter, Kristin; Nordgård, Catherine Taylor; Apelgren, Peter; Säljö, Karin; Solbu, Anita Akbarzadeh; Eliasson, Edwin; Sämfors, Sanna; Sætrang, Henriette Elisabeth Myhr; Asdahl, Lise Cathrine; Thompson, Eric Malcolm; Troedsson, Christofer; Simonsson, Stina; Strand, Berit Løkensgard; Gatenholm, Paul; Kölby, Lars (Journal article; Peer reviewed, 2023)
      Autologous fat grafting is hampered by unpredictable outcomes due to high tissue resorption. Hydrogels based on enzymatically pretreated tunicate nanocellulose (ETC) and alginate (ALG) are biocompatible, safe, and present ...

    • Injective braids, braided operads and double loop spaces 

      Solberg, Mirjam (Master thesis, 2011-06-01)
      We construct the category of B-spaces, which is a braided monoidal diagram category. This category is Quillen equivalent to the category of simplicial sets. The induced equivalence of homotopy categories maps a commutative ...

    • Injuries in Khartoum State, Sudan. Magnitude, consequences and healthcare utilization: a community-based survey 

      El Tayeb, Sally (Doctoral thesis, 2014-06-13)
      Background: Injuries contribute significantly to the global burden of disease accounting for 5.1 million deaths annually. Fatal injuries are the tip of the iceberg and many more who survive an injury suffer the consequences ...