Browsing Bergen Open Research Archive by Author "Nilsen, Rune"
Now showing items 1-20 of 27
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Cellular reactions and mineralization in induced heterotopic bone formation in guinea pigs
Nilsen, Rune (Doctoral thesis, 1981) -
Characterization of an amorphous deposit in the lamina propria in oral snuff users in the Sudan as collagen
Idris, Ali M.; Warnakulasuriya, K. A. A. Saman; Ibrahim, Y. E.; Hartley, R.; Paterson, K.; Patel, B.; Nilsen, Rune; Johnson, N. W. (Peer reviewed; Journal article, 1998-04)Histological and ultrastructural features of 25 oral snuff dipper's lesions with distinctive subepithelial hyaline deposits were investigated. Periodic acid-Schiff reaction with and without diastase digestion demonstrated ... -
The composition of gingival inflammatory cell infiltrates in children studied by enzyme histochemistry
Alcoforado, Gil Alves Pessanha; Kristoffersen, Tore; Johannessen, Anne Christine; Nilsen, Rune (Journal article, 1990-07)Gingival biopsies were obtained from 23 children, aged 5-11 years (8.6 ± 1.8 years). Specimens were taken from areas of the gingiva adjacent to the teeth which were to be extracted because of caries or its sequelae and ... -
Electron microscopy of induced heterotopic bone formation in guinea pigs
Nilsen, Rune (Journal article, 1977)A high yield of osteoid and some mineralized bone was induced in the abdominal muscles following implantation of allogenic demineralised and lyophilized dentine. The following types of cells and reactions were found: A. ... -
Electronmicroscopic study of mineralization in induced heterotopic bone formation in guinea pigs
Nilsen, Rune (Journal article, 1980)Mineralization of heterotopic bone was studied in a bone induction model using allogenic demineralization dentin implanted in the abdominal wall of guinea pigs. There was a high yield of newly formed osteoid and bone as ... -
Enzyme histochemical studies of acid phosphatise isoenzymes in induced heterotopic bone formation in guinea pigs
Nilsen, Rune; Magnusson, Bengt (Journal article, 1981)A bone induction model was used to study the effect of different pretreatments and inhibitors added to the substrate of acid phosphatise. Two different acid phosphatises (AcP) were demonstrated. The AcP of matrix-producing ... -
Enzyme histochemical studies of induced heterotopic cartilage and bone formation in guinea pigs with special references to acid phosphatise. A light and enzyme electron microscopic study
Nilsen, Rune; Magnusson, Bengt (Journal article, 1981)Heterotopic bone and cartilage formation was studied in a bone induction model in abdominal muscles of guinea pigs using demineralized allogenic dentin as inductive material. The light microscopical study showed high ... -
Enzyme histochemistry of induced heterotopic bone formation in guinea pigs
Nilsen, Rune; Magnusson, Bengt (Journal article, 1979)In an experimental bone induction model in guinea-pigs, large amounts of heterotopic osteiod and bone were found after 21 days. A semiquantiative intrasectional analysis of oxidative and hydrolytic enzyme activities in the ... -
Expression of biomarkers (p53, transforming growth factor alpha, epidermal growth factor receptor, c-erbB-2/neu and the proliferative cell nuclear antigen) in oropharyngeal squamous cell carcinomas
Ibrahim, Salah Osman; Lillehaug, Johan; Johannessen, Anne Christine; Liavaag, P. G.; Nilsen, Rune; Vasstrand, Endre N. (Peer reviewed; Journal article, 1999)Using immunohistochemistry, expression of p53, transforming growth factor-alpha (TGF-α), epidermal growth factor receptor (EGFR), c-erbB-2/neu and proliferating cell nuclear antigen (PCNA) was examined in 26 fresh frozen ... -
Immunohistochemical detection of p53 in non-malignant and malignant oral lesions associated with snuff dipping in the Sudan and Sweden
Ibrahim, Salah Osman; Johannessen, Anne Christine; Idris, Ali M.; Hirsch, Jan M.; Vasstrand, Endre N.; Magnusson, Bengt; Nilsen, Rune (Journal article, 1996)Immunohistochemistry was used to examine the expression of p53 in pre-malignant oral lesions and oral squamous-cell carcinomas (SCCs) from Swedish and Sudanese snuff-dippers, as well as in pre-malignant oral lesions and ... -
In Situ Expression of CD40, CD40L (CD154), IL-12, TNF-a, IFN-g and TGF-b1 in Murine Lungs during Slowly Progressive Primary Tuberculosis
Mogga, S. J.; Mustafa, Tehmina; Sviland, Lisbet; Nilsen, Rune (Journal article; Peer reviewed, 2003-09)The distribution and expression of CD40, its ligand CD40L (154) and related cytokines interleukin-12 (IL-12), tumour necrosis factor-α (TNF-α), interferon-γ (IFN-γ) and transforming growth factor-β1 (TGF-β1) were studied ... -
In Situ Expression of Cytokines and Cellular Phenotypes in the Lungs of Mice with Slowly Progressive Primary Tuberculosis
Mustafa, Tehmina; Phyu, S.; Nilsen, Rune; Jonsson, Roland; Bjune, Gunnar Aksel (Peer reviewed; Journal article, 2000-06)The cellular phenotypes and the expression of cytokines were studied in the lungs of mice, using immunohistochemistry, during different phases of slowly progressive primary murine tuberculosis infection. During the first ... -
In situ localization of interferons in psoriatic lesions
Livden, J. K.; Nilsen, Rune; Matre, R. (Peer reviewed; Journal article, 1989-10)An indirect immunofluorescence technique, using murine monoclonal antibodies (MoAbs) against human IFN- and human IFN- was used to study IFNs in cryostat sections from psoriatic skin lesions. The IFNs were more pronounced ... -
Increased Bcl-2 and Reduced Bax Expression in Infected Macrophages in Slowly Progressive Primary Murine Mycobacterium tuberculosis Infection
Mogga, S. J.; Mustafa, Tehmina; Sviland, Lisbet; Nilsen, Rune (Peer reviewed; Journal article, 2002-10)Mycobacterium tuberculosis (MTB) persists in host macrophages (Mφs) because it has developed mechanisms to escape Mφ killing. In vitro studies have shown that MTB can induce and inhibit apoptosis by causing the expression ... -
Increased Expression of Fas Ligand in Human Tuberculosis and Leprosy Lesions: a Potential Novel Mechanism of Immune Evasion in Mycobacterial Infection
Mustafa, Tehmina; Bjune, Gunnar Aksel; Jonsson, Roland; Pando, R. Hernandez; Nilsen, Rune (Peer reviewed; Journal article, 2001-12)To study the location and mechanism of apoptosis within the human tuberculosis (TB) and leprosy lesions, parallel sections were analyzed for mycobacterial antigens (M.Ag), Fas ligand (FasL), Fas, CD68 and Mac387 by ... -
Inferring Atlantic salmon post-smolt migration patterns using genetic assignment
Harvey, Alison C.; Sanchez, Maria Quintela; Glover, Kevin; Karlsen, Ørjan; Nilsen, Rune; Skaala, Øystein; Sægrov, Harald; Kolås, Steinar; Knutar, Sofie; Wennevik, Vidar (Peer reviewed; Journal article, 2019)Understanding migratory patterns is important for predicting and mitigating unwanted consequences of environmental change or anthropogenic challenges on vulnerable species. Wild Atlantic salmon undergo challenging migrations ... -
Microfilaments in cells associated with induced heterotpic bone formation in guinea pigs
Nilsen, Rune (Journal article, 1980)Sera from active chronic hepatitis were used to demonstrate actin microfilaments in cells of a bone-induced model. Demnineralized and freeze-dried allogenic dentine was implanted in the abdominal muscles of Guinea pigs. ... -
Migration of Atlantic salmon post-smolts in a fjord with high infestation pressure of salmon lice
Halttunen, Elina; Gjelland, Karl Øystein; Glover, Kevin; Johnsen, Ingrid Askeland; Serra-Llinares, Rosa-Maria; Skaala, Øystein; Nilsen, Rune; Bjørn, Pål Arne; Karlsen, Ørjan; Finstad, Bengt; Skilbrei, Ove Tommy (Peer reviewed; Journal article, 2018)Understanding Atlantic salmon Salmo salar post-smolt coastal migration behaviour is crucial for predicting their exposure to ecological challenges such as the parasite salmon louse Lepeophtheirus salmonis. We compared the ... -
A Mouse Model for Latent Tuberculosis
Phyu, S.; Mustafa, Tehmina; Hofstad, T.; Nilsen, Rune; Fosse, R.; Bjune, Gunnar Aksel (Peer reviewed; Journal article, 1998-06)The aim of the study was to establish a reproducible murine model for latent tuberculosis. We propose an operational definition of latent murine tuberculosis as a stable Mycobacterium tuberculosis count in lungs and spleens ... -
A Mouse Model for Slowly Progressive Primary Tuberculosis
Mustafa, Tehmina; Phyu, S.; Nilsen, Rune; Jonsson, Roland; Bjune, Gunnar Aksel (Journal article, 1999-08)The progression from primary Mycobacterium tuberculosis infection to disease is usually slow in humans. The aim of this study was to develop and characterize a mouse model for slowly progressive primary tuberculosis, using ...