Browsing Registrations from Cristin by Author "Ueland, Per Magne"
Now showing items 21-40 of 52
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Effect of cod residual protein supplementation on markers of glucose regulation in lean adults: A randomized double-blind study
Vildmyren, Iselin; Halstensen, Alfred; McCann, Adrian; Midttun, Øivind; Ueland, Per Magne; Oterhals, Åge; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2020)Large quantities of protein-rich cod residuals, which are currently discarded, could be utilized for human consumption. Although fish fillet intake is related to beneficial health effects, little is known about the potential ... -
The effect of electroconvulsive therapy (ECT) on serum kynurenine pathway metabolites in late-life depression
Aarsland, Tore Ivar Malmei; Haavik, Jan; Ulvik, Arve; Ueland, Per Magne; Dols, Annemiek; Kessler, Ute (Journal article; Peer reviewed, 2023)Background: Depression is reportedly associated with alterations in kynurenine pathway metabolites (kynurenines). Several kynurenines are involved in glutamate signaling, and some have potentially neurotoxic effects while ... -
The effect of vitamin B12 supplementation during pregnancy on infant growth and development in Nepal: a community-based, double-blind, randomised, placebo-controlled trial
Chandyo, Ram K.; Kvestad, Ingrid; Ulak Chandyo, Manjeswori; Ranjitkar, Suman; Hysing, Mari; Shrestha, Merina; Schwinger, Catherine; McCann, Adrian; Ueland, Per Magne; Basnet, Sudha; Shrestha, Laxman; Strand, Tor Arne (Journal article; Peer reviewed, 2023)Background: Vitamin B12 is required for healthy infant growth and development, but low and marginal vitamin B12 status is endemic in low-income and middle-income countries. We aimed to measure the effect of vitamin B12 ... -
Effects of high intake of cod or salmon on gut microbiota profile, faecal output and serum concentrations of lipids and bile acids in overweight adults: a randomised clinical trial
Bratlie, Marianne; Hagen, Ingrid Valheim; Helland, Anita; Erchinger, Friedemann Georg; Midttun, Øivind; Ueland, Per Magne; Rosenlund, Grethe; Sveier, Harald; Mellgren, Gunnar; Hausken, Trygve; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2020-10-27)Purpose To explore whether high intake of cod or salmon would affect gut microbiota profile, faecal output and serum concentrations of lipids and bile acids. Methods Seventy-six adults with overweight/obesity with no ... -
Effects of vitamin B12 supplementation on neurodevelopment and growth in Nepalese Infants: A randomized controlled trial
Strand, Tor A; Ulak Chandyo, Manjeswori; Hysing, Mari; Ranjitkar, Suman; Kvestad, Ingrid; Shrestha, Merina; Ueland, Per Magne; McCann, Adrian; Shrestha, Prakash S; Shrestha, Laxman P.; Chandyo, Ram K. (Journal article; Peer reviewed, 2020)Background Vitamin B12 deficiency is common and affects cell division and differentiation, erythropoiesis, and the central nervous system. Several observational studies have demonstrated associations between biomarkers ... -
Elevated plasma cystathionine is associated with increased risk of mortality among patients with suspected or established coronary heart disease
Dhar, Indu; Lysne, Vegard; Svingen, Gard Frodahl Tveitevåg; Ueland, Per Magne; Gregory, Jesse F.; Bønaa, Kaare Harald; Nygård, Ottar (Journal article; Peer reviewed, 2019)Background Elevated circulating cystathionine levels are related to atherosclerotic cardiovascular disease, a leading cause of death globally. Objective We investigated whether plasma cystathionine was associated with ... -
Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults
Zahed, Hana; Johansson, Mattias; Ueland, Per Magne; Midttun, Øivind; Milne, Roger L.; Giles, Graham G.; Manjer, Jonas; Sandsveden, Malte; Langhammer, Arnulf; Sørgjerd, Elin Pettersen; Grankvist, Kjell; Johansson, Mikael; Freedman, Neal D.; Huang, Wen-Yi; Chen, Chu; Prentice, Ross; Stevens, Victoria L.; Wang, Ying; Le Marchand, Loic; Wilkens, Lynne R.; Weinstein, Stephanie J.; Albanes, Demetrius; Cai, Qiuyin; Blot, William J.; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Shu, Xiao-Ou; Zheng, Wei; Yuan, Jian-Min; Koh, Woon-Puay; Visvanathan, Kala; Sesso, Howard D.; Zhang, Xuehong; Gaziano, J. Michael; Fanidi, Anouar; Muller, David; Brennan, Paul; Guida, Florence; Robbins, Hilary A. (Journal article; Peer reviewed, 2021)Imbalances of blood biomarkers are associated with disease, and biomarkers may also vary non-pathologically across population groups. We described variation in concentrations of biomarkers of one-carbon metabolism, vitamin ... -
Exploratory analyses on the effect of time since last meal on concentrations of amino acids, lipids, one-carbon metabolites, and vitamins in the Hordaland Health Study
Anfinsen, Åslaug Matre; Rosendahl-Riise, Hanne; Nygård, Ottar Kjell; Tell, Grethe S.; Ueland, Per Magne; Ulvik, Arve; McCann, Adrian; Dierkes, Jutta; Lysne, Vegard (Journal article; Peer reviewed, 2023)Purpose Dietary intake may have pronounced effects on circulating biomarker concentrations. Therefore, the aim was to provide a descriptive overview of serum metabolite concentrations in relation to time since last meal, ... -
Five salmon dinners per week were not sufficient to prevent the reduction in serum vitamin D in autumn at 60° north latitude: A randomised trial
Bratlie, Marianne; Hagen, Ingrid Valheim; Helland, Anita; Midttun, Øivind; Ulvik, Arve; Rosenlund, Grethe; Sveier, Harald; Mellgren, Gunnar; Ueland, Per Magne; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2020)Low serum concentrations of several vitamins have been linked to increased risk of diseases including insulin resistance and type 2 diabetes (T2D). Fish is a good source of several vitamins, and the prevalence of T2D is ... -
Folate – a scoping review for Nordic Nutrition Recommendations 2023
Monsen, Anne-Lise Bjørke; Ueland, Per Magne (Journal article; Peer reviewed, 2023)Folate is an essential micronutrient for normal development and metabolic function, and folate deficiency is associated with an increased risk of cancer, cardiovascular disease, mental dysfuntion and negative pregnancy ... -
Healthy Nordic diet and associations with plasma concentrations of metabolites in the choline oxidation pathway: a cross-sectional study from Northern Sweden
Hesselink, André; Winkvist, Anna; Lindahl, Bernt; Ueland, Per Magne; Schneede, Jørn; Johansson, Ingegerd; Karlsson, Therese (Journal article; Peer reviewed, 2023-05-17)Background: The choline oxidation pathway and metabolites involved have been linked to diseases including cardiovascular disease, type 2 diabetes and cancer. A healthy Nordic diet is a recently defined dietary pattern ... -
Higher concentrations of kynurenic acid in CSF are associated with the slower clinical progression of Alzheimer's disease
Knapskog, Anne Brita; Aksnes, Mari; Edwin, Trine Holt; Ueland, Per Magne; Ulvik, Arve; Fang, Fei; Eldholm, Rannveig Sakshaug; Halaas, Nathalie Bodd; Saltvedt, Ingvild Tina; Giil, Lasse Melvær; Watne, Leiv (Journal article; Peer reviewed, 2023)Introduction: The kynurenine pathway's (KP) malfunction is closely related to Alzheimer's disease (AD), for antagonistic kynurenic acid (KA) and agonistic quinolinic acid act on the N-methyl-D-aspartate receptor, a possible ... -
Impaired glucose utilization in the brain of patients with delirium following hip fracture
Titlestad, Irit; Watne, Leiv; Caplan, Gideon A.; McCann, Adrian; Ueland, Per Magne; Neerland, Bjørn Erik; Myrstad, Marius; Halaas, Nathalie Bodd; Pollmann, Christian Thomas; Henjum, Kristi; Ranhoff, Anette Hylen; Solberg, Lene Bergendal; Figved, Wender; Cunningham, Colm; Melvær, Giil Lasse (Journal article; Peer reviewed, 2024)Alterations in brain energy metabolism have long been proposed as one of several neurobiological processes contributing to delirium. This is supported by previous findings of altered CSF lactate and neuron-specific enolase ... -
Inflammation, sex, blood pressure changes and hypertension in midlife: the Hordaland Health Study
Kringeland, Ester Anne; Gerdts, Eva; Ulvik, Arve; Tell, Grethe S.; Igland, Jannicke; Haugsgjerd, Teresa Risan; Ueland, Per Magne; Midtbø, Helga Bergljot (Journal article; Peer reviewed, 2023)Our aim was to test sex-specific associations of circulating markers of inflammation with blood pressure (BP) and incident hypertension in midlife. Participants in the Hordaland Health study (n = 3280, 56% women, mean age ... -
The Kynurenine Pathway Is Upregulated by Methyl-deficient Diet and Changes Are Averted by Probiotics
Tillmann, Sandra; Awwad, Hussain M.; MacPherson, Chad W.; Happ, Denise F.; Treccani, Giulia; Geisel, Juergen; Tompkins, Thomas A.; Ueland, Per Magne; Wegener, Gregers; Obeid, Rima (Journal article; Peer reviewed, 2021)Scope Probiotics exert immunomodulatory effects and may influence tryptophan metabolism in the host. Deficiency of nutrients related to C1 metabolism might stimulate inflammation by enhancing the kynurenine pathway. This ... -
Kynurenine Pathway Metabolites in the Blood and Cerebrospinal Fluid Are Associated with Human Aging
Solvang, Stein-Erik Hafstad; Hodge, Allison; Watne, Leiv; Cabral-Marques, Otavio; Nordrehaug, Jan Erik; Giles, Graham G.; Dugué, Pierre-Antoine; Nygård, Ottar Kjell; Ueland, Per Magne; McCann, Adrian; Idland, Ane-Victoria; Midttun, Øivind; Ulvik, Arve; Halaas, Nathalie Bodd; Tell, Grethe S.; Melvær, Giil Lasse (Journal article; Peer reviewed, 2022)The kynurenine pathway is implicated in aging, longevity, and immune regulation, but longitudinal studies and assessment of the cerebrospinal fluid (CSF) are lacking. We investigated tryptophan (Trp) and downstream kynurenine ... -
Kynurenines, Neuropsychiatric Symptoms, and Cognitive Prognosis in Patients with Mild Dementia
Solvang, Stein-Erik Hafstad; Nordrehaug, Jan Erik; Aarsland, Dag; Lange, Johannes; Ueland, Per Magne; McCann, Adrian; Midttun, Øivind; Tell, Grethe S.; Melvær, Giil Lasse (Journal article; Peer reviewed, 2019)Introduction: Circulating tryptophan (Trp) and its downstream metabolites, the kynurenines, are potentially neuroactive. Consequently, they could be associated with neuropsychiatric symptoms and cognitive prognosis in ... -
Lipid parameters and vitamin A modify cardiovascular risk prediction by plasma neopterin
Dhar, Indu; Siddique, Sumia; Pedersen, Eva Kristine Ringdal; Svingen, Gard FT; Lysne, Vegard; Olsen, Thomas; Nilsen, Dennis W.T.; Nordrehaug, Jan Erik; Midttun, Øivind; Ueland, Per Magne; Tell, Grethe S; Nygård, Ottar (Journal article; Peer reviewed, 2020)Objectives Oxidised cholesterol metabolites are linked to increased production of the active vitamin A (Vit-A) form and monocyte/macrophage activation, which may be reflected by neopterin, a marker of both interferon-γ–mediated ... -
Metabolic analysis of amino acids and vitamin B6 pathways in lymphoma survivors with cancer related chronic fatigue
Fosså, Alexander; Smeland, Knut Bjøro; Fluge, Øystein; Tronstad, Karl Johan; Loge, Jon Håvard; Midtun, Øyvind; Ueland, Per Magne; Kiserud, Cecilie E. (Journal article; Peer reviewed, 2020)Chronic cancer-related fatigue (CF) is a common and distressing condition in a subset of cancer survivors and common also after successful treatment of malignant lymphoma. The etiology and pathogenesis of CF is unknown, ... -
Microheterogeneity and preanalytical stability of protein biomarkers of inflammation and renal function
Gao, Jie; Ulvik, Arve; McCann, Adrian; Ueland, Per Magne; Meyer, Klaus (Journal article; Peer reviewed, 2021)Protein biomarker microheterogeneity has attracted increasing attention in epidemiological and clinical research studies. Knowledge concerning the preanalytical stability of proteins is paramount to assess the biological ...