Browsing Registrations from Cristin by Author "Valk, Peter J. M."
Now showing items 1-3 of 3
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The added value of multi-state modelling in a randomized controlled trial: The HOVON 102 study re-analyzed
Bakunina, Katerina; Putter, Hein; Versluis, Jurjen; Koster, Eva A. S.; van der Holt, Bronno; Manz, Markus G.; Breems, Dimitri A.; Gjertsen, Bjørn Tore; Cloos, Jacqueline; Valk, Peter J. M.; Passweg, Jakob; Pabst, Thomas; Ossenkoppele, Gert J.; Löwenberg, Bob; Cornelissen, Jan J.; de Wreede, Liesbeth C. (Journal article; Peer reviewed, 2022)Clofarabine is an active antileukemic drug for subgroups of patients with acute myeloid leukemia (AML). Multi-state models can provide additional insights to supplement the original intention-to-treat analysis of randomized ... -
FLT3-ITD mutations in acute myeloid leukaemia – molecular characteristics, distribution and numerical variation
Engen, Caroline; Hellesøy, Monica; Grob, Tim; Al Hinai, Adil; Brendehaug, Atle; Wergeland, Line; Bedringaas, Siv Lise; Hovland, Randi; Valk, Peter J. M.; Gjertsen, Bjørn T. (Journal article; Peer reviewed, 2021)Recurrent somatic internal tandem duplications (ITD) in the FMS-like tyrosine kinase 3 (FLT3) gene characterise approximately one third of patients with acute myeloid leukaemia (AML), and FLT3-ITD mutation status guides ... -
Sex disparity in acute myeloid leukaemia with FLT3 internal tandem duplication mutations: implications for prognosis
Hellesøy, Monica; Engen, Caroline Benedicte Nitter; Grob, Tim; Löwenberg, Bob; Valk, Peter J. M.; Gjertsen, Bjørn T. (Journal article; Peer reviewed, 2021)Incidence, molecular presentation and outcome of acute myeloid leukaemia (AML) are influenced by sex, but little attention has been directed at untangling sex-related molecular and phenotypic differences between female and ...