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dc.contributor.authorThortveit, Erik Thomas
dc.contributor.authorAase, Audun
dc.contributor.authorPetersen, Lizette Balle
dc.contributor.authorLorentzen, Åslaug Rudjord
dc.contributor.authorMygland, Åse
dc.contributor.authorLjøstad, Unn
dc.date.accessioned2021-03-12T11:41:45Z
dc.date.available2021-03-12T11:41:45Z
dc.date.created2021-01-22T11:42:19Z
dc.date.issued2020
dc.PublishedActa Neurologica Scandinavica. 2020, 142 (3), 260-266.
dc.identifier.issn0001-6314
dc.identifier.urihttps://hdl.handle.net/11250/2733143
dc.descriptionPostponed access: the file will be accessible after 2021-05-11en_US
dc.description.abstractObjectives Whether tick‐borne infections can cause chronic subjective health complaints is heavily debated. If such a causal connection exists, one would expect to find more health complaints among individuals exposed to tick‐borne infections than among non‐exposed. In this study, we aimed to assess if exposure to tick‐borne infections earlier in life, evaluated by examination of serum for IgG antibodies to tick‐borne microbes, was associated with self‐reported somatic symptom load. Materials & Methods All individuals with residential address in Søgne municipality in southern Norway, aged 18‐69 years, were invited to participate in the study. Blood samples were analyzed for IgG antibodies to different tick‐borne microbes, and somatic symptom load was charted by the Patient Health Questionnaire‐15 (PHQ‐15). Results Out of 7424 invited individuals, 2968 (40.0%) were included in the study. We detected IgG antibodies to Borrelia burgdorferi sensu lato (Bb) in 22.9% (95% CI 21.4‐24.4). Bb seropositive individuals reported less frequently moderate to severe somatic symptom load (ie, PHQ‐15 sum score ≥ 10) than seronegative individuals (12.5% versus 17.7%, difference 5.2% [95% 2.1‐8.0]). However, when adjusting for several other variables in a multivariable linear regression model, presence of serum IgG antibodies to Bb was not associated with somatic symptom load. Presence of IgG antibodies to other tick‐borne microbes than Bb, or seropositivity to at least two microbes, was also not associated with somatic symptom load. Conclusion Presence of serum IgG antibodies to tick‐borne microbes was not associated with self‐reported somatic symptom load.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.titleSubjective health complaints and exposure to tick-borne infections in southern Norwayen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionacceptedVersionen_US
dc.rights.holder© 2020 John Wiley & Sons A/S.en_US
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1
dc.identifier.doi10.1111/ane.13263
dc.identifier.cristin1877066
dc.source.journalActa Neurologica Scandinavicaen_US
dc.source.40142
dc.source.143
dc.source.pagenumber260-266en_US
dc.relation.projectAndre: 2015113en_US
dc.relation.projectHelse Sør-Øst RHF: 2014107en_US
dc.identifier.citationActa Neurologica Scandinavica. 2020, 142 (3), 260-266.en_US
dc.source.volume142en_US
dc.source.issue3en_US


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