dc.contributor.author | Jensen, Caroline | |
dc.contributor.author | Dale, Hanna Fjeldheim | |
dc.contributor.author | Hausken, Trygve | |
dc.contributor.author | Hatlebakk, Jan Gunnar | |
dc.contributor.author | Brønstad, Ingeborg | |
dc.contributor.author | Lied, Gülen Arslan | |
dc.contributor.author | Hoff, Dag Arne Lihaug | |
dc.date.accessioned | 2021-03-18T13:55:41Z | |
dc.date.available | 2021-03-18T13:55:41Z | |
dc.date.created | 2020-07-09T12:47:47Z | |
dc.date.issued | 2020 | |
dc.Published | Nutrients. 2020, 12:1991 (7), 1-15. | |
dc.identifier.issn | 2072-6643 | |
dc.identifier.uri | https://hdl.handle.net/11250/2734273 | |
dc.description.abstract | The risk of cardiovascular diseases and type 2 diabetes mellitus are increased in subjects with metabolic syndrome (MetS), and hydrolyzed fish protein may have favorable effects on metabolic health. Here, we investigated the effect of 8 weeks supplementation with 4 g of cod protein hydrolysate (CPH) on glucose metabolism, lipid profile and body composition in individuals with MetS in a double-blind, randomized intervention study with a parallel-group design. Subjects received a daily supplement of CPH (n = 15) or placebo (n = 15). Primary outcomes were serum fasting and postprandial glucose levels. Secondary outcomes were fasting and postprandial insulin and glucagon-like peptide 1 (GLP-1), fasting lipid concentrations and body composition. No difference was observed between CPH and placebo for insulin, glucose or GLP-1 after 8 weeks intervention. Fasting triacylglycerol decreased in both the CPH group and placebo group, with no change between groups. Fasting total cholesterol and low-density lipoprotein cholesterol decreased significantly within both groups from baseline to study end, but no difference was observed between the two groups. In conclusion, supplementing with a low dose of CPH in subjects with MetS for 8 weeks had no effect on fasting or postprandial levels of insulin, glucose or GLP-1, lipid profile or body composition. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | MDPI | en_US |
dc.relation.uri | https://www.mdpi.com/2072-6643/12/7/1991 | |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Supplementation with Low Doses of a Cod Protein Hydrolysate on Glucose Regulation and Lipid Metabolism in Adults with Metabolic Syndrome: A Randomized, Double-Blind Study | en_US |
dc.type | Journal article | en_US |
dc.type | Peer reviewed | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2020 The Authors | en_US |
dc.source.articlenumber | 1991 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.doi | 10.3390/nu12071991 | |
dc.identifier.cristin | 1819076 | |
dc.source.journal | Nutrients | en_US |
dc.source.40 | 12:1991 | |
dc.source.14 | 7 | |
dc.identifier.citation | Nutrients. 2020, 12(7):1991 | en_US |
dc.source.volume | 12 | en_US |
dc.source.issue | 7 | en_US |