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dc.contributor.authorJensen, Caroline
dc.contributor.authorDale, Hanna Fjeldheim
dc.contributor.authorHausken, Trygve
dc.contributor.authorHatlebakk, Jan Gunnar
dc.contributor.authorBrønstad, Ingeborg
dc.contributor.authorLied, Gülen Arslan
dc.contributor.authorHoff, Dag Arne Lihaug
dc.date.accessioned2021-03-18T13:55:41Z
dc.date.available2021-03-18T13:55:41Z
dc.date.created2020-07-09T12:47:47Z
dc.date.issued2020
dc.PublishedNutrients. 2020, 12:1991 (7), 1-15.
dc.identifier.issn2072-6643
dc.identifier.urihttps://hdl.handle.net/11250/2734273
dc.description.abstractThe risk of cardiovascular diseases and type 2 diabetes mellitus are increased in subjects with metabolic syndrome (MetS), and hydrolyzed fish protein may have favorable effects on metabolic health. Here, we investigated the effect of 8 weeks supplementation with 4 g of cod protein hydrolysate (CPH) on glucose metabolism, lipid profile and body composition in individuals with MetS in a double-blind, randomized intervention study with a parallel-group design. Subjects received a daily supplement of CPH (n = 15) or placebo (n = 15). Primary outcomes were serum fasting and postprandial glucose levels. Secondary outcomes were fasting and postprandial insulin and glucagon-like peptide 1 (GLP-1), fasting lipid concentrations and body composition. No difference was observed between CPH and placebo for insulin, glucose or GLP-1 after 8 weeks intervention. Fasting triacylglycerol decreased in both the CPH group and placebo group, with no change between groups. Fasting total cholesterol and low-density lipoprotein cholesterol decreased significantly within both groups from baseline to study end, but no difference was observed between the two groups. In conclusion, supplementing with a low dose of CPH in subjects with MetS for 8 weeks had no effect on fasting or postprandial levels of insulin, glucose or GLP-1, lipid profile or body composition.en_US
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.relation.urihttps://www.mdpi.com/2072-6643/12/7/1991
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleSupplementation with Low Doses of a Cod Protein Hydrolysate on Glucose Regulation and Lipid Metabolism in Adults with Metabolic Syndrome: A Randomized, Double-Blind Studyen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2020 The Authorsen_US
dc.source.articlenumber1991en_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.doi10.3390/nu12071991
dc.identifier.cristin1819076
dc.source.journalNutrientsen_US
dc.source.4012:1991
dc.source.147
dc.identifier.citationNutrients. 2020, 12(7):1991en_US
dc.source.volume12en_US
dc.source.issue7en_US


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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal