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dc.contributor.authorSkaar, Elisabeth
dc.contributor.authorØksnes, Anja
dc.contributor.authorEide, Leslie SP
dc.contributor.authorNorekvål, Tone Merete
dc.contributor.authorRanhoff, Anette Hylen
dc.contributor.authorNordrehaug, Jan Erik
dc.contributor.authorForman, Daniel Edward
dc.contributor.authorSchoennberger, Andreas W.
dc.contributor.authorHufthammer, Karl Ove
dc.contributor.authorKuiper, Karel Kier-Jan
dc.contributor.authorBleie, Øyvind
dc.contributor.authorPacker, Erik
dc.contributor.authorLangørgen, Jørund
dc.contributor.authorHaaverstad, Rune
dc.contributor.authorSchaufel, Margrethe Aase
dc.description.abstractAims The objective of this study was to examine baseline frailty status (including cognitive deficits) and important clinical outcomes, to inform shared decision-making in older adults receiving transcatheter aortic valve implantation (TAVI). Methods and results We conducted a prospective, observational study of 82 TAVI patients, recruited 2013 to 2015, with 2-year follow-up. Mean age was 83 years (standard deviation (SD) 4.7). Eighteen percent of the patients were frail, as assessed with an 8-item frailty scale. Fifteen patients (18%) had a Mini-Mental Status Examination (MMSE) score below 24 points at baseline, indicating cognitive impairment or dementia and five patients had an MMSE below 20 points. Mean New York Heart Association (NYHA) class at baseline and 6 months was 2.5 (SD 0.6) and 1.4 (SD 0.6), (p < 0.001). There was no change in mean Nottingham Extended Activities of Daily Living (NEADL) scale between baseline and 6 months, 54.2 (SD 11.5) and 54.5 (SD 10.3) points, respectively, mean difference 0.3 (p = 0.7). At 2 years, six patients (7%) had died, four (5%, n = 79) lived in a nursing home, four (5%) suffered from disabling stroke, and six (7%) contracted infective endocarditis. Conclusions TAVI patients had improvement in symptoms and maintenance of activity of daily living at 6 months. They had low mortality and most patients lived in their own home 2 years after TAVI. Complications like death, stroke, and endocarditis occurred. Some patients had cognitive impairment before the procedure which might influence decision-making. Our findings may be used to develop pre-TAVI decision aids.en_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.titleBaseline frailty status and outcomes important for shared decision‑making in older adults receiving transcatheter aortic valve implantation, a prospective observational studyen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.rights.holderCopyright The Author(s) 2020en_US
dc.source.journalAging Clinical and Experimental Researchen_US
dc.identifier.citationAging Clinical and Experimental Research. 2021, 33, 345–352.en_US

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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal