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dc.contributor.authorGarrison, Laura
dc.contributor.authorVašíček, Jakub
dc.contributor.authorCraven, Alexander R.
dc.contributor.authorGrüner, Renate
dc.contributor.authorSmit, Noeska Natasja
dc.contributor.authorBruckner, Stefan
dc.date.accessioned2021-06-28T11:31:21Z
dc.date.available2021-06-28T11:31:21Z
dc.date.created2020-10-06T14:55:05Z
dc.date.issued2020
dc.PublishedComputers & graphics. 2020, 92 1-12.
dc.identifier.issn0097-8493
dc.identifier.urihttps://hdl.handle.net/11250/2761631
dc.description.abstractMagnetic resonance spectroscopy (MRS) is an advanced biochemical technique used to identify metabolic compounds in living tissue. While its sensitivity and specificity to chemical imbalances render it a valuable tool in clinical assessment, the results from this modality are abstract and difficult to interpret. With this design study we characterized and explored the tasks and requirements for evaluating these data from the perspective of a MRS research specialist. Our resulting tool, SpectraMosaic, links with upstream spectroscopy quantification software to provide a means for precise interactive visual analysis of metabolites with both single- and multi-peak spectral signatures. Using a layered visual approach, SpectraMosaic allows researchers to analyze any permutation of metabolites in ratio form for an entire cohort, or by sample region, individual, acquisition date, or brain activity status at the time of acquisition. A case study with three MRS researchers demonstrates the utility of our approach in rapid and iterative spectral data analysis.en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.urihttps://www.sciencedirect.com/science/article/pii/S0097849320301199?via%3Dihub
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleInteractive visual exploration of metabolite ratios in MR spectroscopy studiesen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2020 The Authorsen_US
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode2
dc.identifier.doi10.1016/j.cag.2020.08.001
dc.identifier.cristin1837657
dc.source.journalComputers & graphicsen_US
dc.source.4092
dc.source.pagenumber1-12en_US
dc.relation.projectTrond Mohn stiftelse: 811255en_US
dc.relation.projectTrond Mohn stiftelse: 813558en_US
dc.identifier.citationComputers & graphics. 2020, 92, 1-12en_US
dc.source.volume92en_US


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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal