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dc.contributor.authorGjerde, Anna
dc.contributor.authorReisæter, Anna Varberg
dc.contributor.authorSkrunes, Rannveig
dc.contributor.authorMarti, Hans-Peter
dc.contributor.authorVikse, Bjørn Egil
dc.date.accessioned2021-07-01T10:56:49Z
dc.date.available2021-07-01T10:56:49Z
dc.date.created2020-10-29T00:15:02Z
dc.date.issued2020
dc.PublishedAmerican Society of Nephrology. Clinical Journal. 2020, 15 (10), 1413-1423.
dc.identifier.issn1555-9041
dc.identifier.urihttps://hdl.handle.net/11250/2762772
dc.description.abstractBackground and objectives: Previous studies have shown that individuals with low birth weight (LBW) or small for gestational age (SGA) have higher risk of kidney failure. This study investigates birth-related exposures and risk of CKD and other kidney diagnoses. Design, setting, participant, & measurements: The Medical Birth Registry of Norway has registered extensive medical data on all births in Norway since 1967. The Norwegian Patient Registry has registered diagnostic codes for all admissions and outpatient visits to Norwegian hospitals since 2008. Data from these registries were linked, and risk of CKD and other groups of kidney disease were analyzed using logistic regression statistics. LBW (below the tenth percentile), SGA (birth weight below the tenth percentile for gestational age), and preterm birth (<37 weeks) were analyzed as exposures. Results: A total of 2,663,010 individuals were included. After a mean follow-up of 26 years (maximum 50 years), 4495 had been diagnosed with CKD and 12,818 had been diagnosed with other groups of kidney disease. LBW was associated with an odds ratio (OR) for CKD of 1.72 (95% confidence interval [95% CI], 1.60 to 1.90), SGA with an OR of 1.79 (95% CI, 1.65 to 1.94), and preterm birth with an OR of 1.48 (95% CI, 1.33 to 1.66). Analyses using diagnosis of CKD at stages 3–5 as end point showed similar results. Results were similar for men and women. We analyzed adjusted ORs for other groups of kidney disease and found that LBW was associated with an adjusted OR of 1.44 (95% CI, 1.33 to 1.56) for acute kidney disease, 1.24 (95% CI, 1.14 to 1.36) for GN, 1.35 (95% CI, 1.17 to 1.56) for cystic kidney disease, and 1.15 (95% CI, 1.06 to 1.25) for kidney disease resulting from kidney or urinary tract malformations. Conclusions: LBW, SGA, and preterm birth are associated with higher risk of CKD in the first 50 years of life. Risk of other groups of kidney disease was less pronounced.en_US
dc.language.isoengen_US
dc.publisherAmerican Society of Nephrologyen_US
dc.titleIntrauterine growth restriction and risk of diverse forms of kidney disease during the first 50 years of lifeen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionacceptedVersionen_US
dc.rights.holderCopyright 2020 by the American Society of Nephrologyen_US
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode2
dc.identifier.doi10.2215/CJN.04080320
dc.identifier.cristin1843128
dc.source.journalClinical Journal of the American Society of Nephrologyen_US
dc.source.4015
dc.source.1410
dc.source.pagenumber1413-1423en_US
dc.identifier.citationClinical Journal of the American Society of Nephrology. 2020, 15 (10), 1413-1423.en_US
dc.source.volume15en_US
dc.source.issue10en_US


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