Characterization of Schistosoma mansoni Glutamate-Gated Chloride Channels
Journal article, Peer reviewed
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Original versionMethods in molecular biology. 2020, 2151, 173-183. 10.1007/978-1-0716-0635-3_14
Electrophysiology is the standard method for characterizing ion channel function. Two-electrode voltage clamp is a robust and relatively simple version which can be applied to the characterization of glutamate-gated chloride channels from Schistosoma mansoni, a potential schistomicidal target. Here, the method is described in detail, with an emphasis on the investigation of S. mansoni. GluCls.