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dc.contributor.authorGilhus, Nils Erik
dc.date.accessioned2021-08-10T13:43:48Z
dc.date.available2021-08-10T13:43:48Z
dc.date.created2021-04-05T14:48:26Z
dc.date.issued2021
dc.identifier.issn0960-8966
dc.identifier.urihttps://hdl.handle.net/11250/2767222
dc.descriptionUnder embargo until: 2021-12-18en_US
dc.description.abstractMyasthenia gravis is characterized by muscle weakness and fatigue. As sustained muscle use increases the weakness, the value of physical training programs has previously been questioned. This is a review to clarify the safety and usefulness of systematic training in myasthenia gravis, based on a systematic search in available databases using the relevant key words. Ten intervention studies including 159 patients with generalized disease have been published regarding the effect of systematic physical training, three of them on respiratory muscles. Muscle strength improved, and in the majority of the studies also daily function and quality of life. The feeling of fatigue not directly related to actual muscle weakness was less influenced by physical training. Continuous training was necessary to maintain the improved function. Physical training and exercise are safe in myasthenia gravis. This can improve both muscle strength and daily function. Type and intensity of systematic training should be adapted in the individual patient. A minimum of 150 min of exercise per week is recommended for myasthenia gravis patients with mild and moderate disease.en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.no*
dc.titlePhysical training and exercise in myasthenia gravisen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionacceptedVersionen_US
dc.rights.holderCopyright 2020 Elsevieren_US
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1
dc.identifier.doi10.1016/j.nmd.2020.12.004
dc.identifier.cristin1902114
dc.source.journalNeuromuscular Disordersen_US
dc.source.pagenumber169-173en_US
dc.identifier.citationNeuromuscular Disorders. 2021, 31 (3), 169-173.en_US
dc.source.volume31en_US
dc.source.issue3en_US


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Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal
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