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dc.contributor.authorArach, Agnes Anna
dc.contributor.authorTumwine, James K.
dc.contributor.authorNakasujja, Noeline
dc.contributor.authorNdeezi, Grace
dc.contributor.authorKiguli, Juliet
dc.contributor.authorMukunya, David
dc.contributor.authorOdongkara, Beatrice
dc.contributor.authorAchora, Vincentina
dc.contributor.authorTongun, Justin Bruno
dc.contributor.authorMusaba, Milton W.
dc.contributor.authorNapyo, Agnes
dc.contributor.authorTylleskär, Thorkild
dc.contributor.authorNankabirwa, Victoria
dc.description.abstractBackground: Perinatal mortality in Uganda remains high at 38 deaths/1,000 births, an estimate greater than the every newborn action plan (ENAP) target of ≤24/1,000 births by 2030. To improve perinatal survival, there is a need to understand the persisting risk factors for death. Objective: We determined the incidence, risk factors, and causes of perinatal death in Lira district, Northern Uganda. Methods: This was a community-based prospective cohort study among pregnant women in Lira district, Northern Uganda. Female community volunteers identified pregnant women in each household who were recruited at ≥28 weeks of gestation and followed until 50 days postpartum. Information on perinatal survival was gathered from participants within 24 hours after childbirth and at 7 days postpartum. The cause of death was ascertained using verbal autopsies. We used generalized estimating equations of the Poisson family to determine the risk factors for perinatal death. Results: Of the 1,877 women enrolled, the majority were ≤30 years old (79.8%), married or cohabiting (91.3%), and had attained only a primary education (77.7%). There were 81 perinatal deaths among them, giving a perinatal mortality rate of 43/1,000 births [95% confidence interval (95% CI: 35, 53)], of these 37 were stillbirths (20 deaths/1,000 total births) and 44 were early neonatal deaths (23 deaths/1,000 live births). Birth asphyxia, respiratory failure, infections and intra-partum events were the major probable contributors to perinatal death. The risk factors for perinatal death were nulliparity at enrolment (adjusted IRR 2.7, [95% CI: 1.3, 5.6]) and maternal age >30 years (adjusted IRR 2.5, [95% CI: 1.1, 5.8]). Conclusion: The incidence of perinatal death in this region was higher than had previously been reported in Uganda. Risk factors for perinatal mortality were nulliparity and maternal age >30 years. Pregnant women in this region need improved access to care during pregnancy and childbirth.en_US
dc.publisherTaylor and Francisen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.titlePerinatal death in Northern Uganda: incidence and risk factors in a community-based prospective cohort studyen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.rights.holderCopyright 2021 The Author(s).en_US
dc.source.journalGlobal Health Actionen_US
dc.identifier.citationGlobal Health Action. 2021, 14 (1), 1859823.en_US

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