dc.contributor.author | Advani, Rajiv | |
dc.contributor.author | Strømsnes, Torbjørn Austveg | |
dc.contributor.author | Stjernstrøm, Espen | |
dc.contributor.author | Lugg, Sebastian T. | |
dc.date.accessioned | 2021-12-01T07:34:47Z | |
dc.date.available | 2021-12-01T07:34:47Z | |
dc.date.created | 2021-08-27T15:54:07Z | |
dc.date.issued | 2021-08-18 | |
dc.identifier.issn | 1477-9560 | |
dc.identifier.uri | https://hdl.handle.net/11250/2832226 | |
dc.description.abstract | Background: The coronavirus disease (COVID-19) pandemic has led to an unprecedented worldwide burden of disease. However, little is known of the longer-term implications and consequences of COVID-19. One of these may be a COVID-19 associated coagulopathy that can present as a venous thromboembolism (VTE) and further, as multiple paradoxical cerebral emboli.
Case presentation: A 51 year old man presented to the emergency department with multiple simultaneous embolic cerebral infarctions 11 months after mild COVID-19. In the subacute phase of the COVID-19 illness the patient developed increasing shortness of breath and was found to have an elevated D-dimer and multiple bilateral segmental pulmonary emboli. He was subsequently treated with 3 months of anticoagulation for a provoked VTE. The patient then presented 11 months after the initial COVID-19 diagnosis with multiple simultaneous cerebral infarctions where no traditional underlying stroke etiology was determined. A patent foramen ovale (PFO) and an elevated D-dimer were found suggesting a paradoxical thromboembolic event due to an underlying coagulopathy.
Conclusions: This case report highlights the one of the potentially more serious complications of long-term COVID-19 where VTE due to a persistent coagulopathy is seen almost a year after the initial illness. Due to the highly prevalent nature of PFO in the general population, VTE due to COVID-19 associated coagulopathy could lead to ischemic stroke. This case report highlights the possibility for an underlying COVID-19 associated coagulopathy which may persist for many months and beyond the initial illness. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | BMC | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Multiple simultaneous embolic cerebral infarctions 11 months after COVID-19 | en_US |
dc.type | Journal article | en_US |
dc.type | Peer reviewed | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2021 the authors | en_US |
dc.source.articlenumber | 57 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.doi | 10.1186/s12959-021-00304-8 | |
dc.identifier.cristin | 1929401 | |
dc.source.journal | Thrombosis Journal | en_US |
dc.identifier.citation | Thrombosis Journal. 2021, 19, 57. | en_US |
dc.source.volume | 19 | en_US |