dc.contributor.author | Porter, Chad K | |
dc.contributor.author | Detizio, Katherine J | |
dc.contributor.author | Maier, Nicole | |
dc.contributor.author | Testa, Kayla J | |
dc.contributor.author | Talaat, Kawsar R | |
dc.contributor.author | Chen, Wilbur H | |
dc.contributor.author | Lyon, Caroline E | |
dc.contributor.author | Gutierrez, Ramiro L | |
dc.contributor.author | Frenck, Robert | |
dc.contributor.author | Isidean, Sandra D | |
dc.contributor.author | Kaminski, Robert W | |
dc.contributor.author | Alcala, Ashley N | |
dc.contributor.author | Hanevik, Kurt | |
dc.contributor.author | Sawe, Frederick | |
dc.contributor.author | Kirkpatrick, Beth D | |
dc.contributor.author | Louis Bourgeois, Bourgeois | |
dc.date.accessioned | 2022-03-16T13:28:47Z | |
dc.date.available | 2022-03-16T13:28:47Z | |
dc.date.created | 2021-11-15T15:11:29Z | |
dc.date.issued | 2022 | |
dc.identifier.issn | 1740-7745 | |
dc.identifier.uri | https://hdl.handle.net/11250/2985593 | |
dc.description.abstract | The use of the controlled human infection model to facilitate product development and to advance understanding of host-pathogen interactions is of increasing interest. While administering a virulent (or infective) organism to a susceptible host necessitates an ongoing evaluation of safety and ethical considerations, a central theme in conducting these studies in a safe and ethical manner that yields actionable data is their conduct in facilities well-suited to address their unique attributes. To that end, we have developed a framework for evaluating potential sites in which to conduct inpatient enteric controlled human infection model to ensure consistency and increase the likelihood of success. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Sage | en_US |
dc.rights | Navngivelse-Ikkekommersiell 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/deed.no | * |
dc.title | A site assessment tool for inpatient controlled human infection models for enteric disease pathogens | en_US |
dc.type | Journal article | en_US |
dc.type | Peer reviewed | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2021 The Author(s) | en_US |
dc.source.articlenumber | 116-118 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.doi | 10.1177/17407745211052473 | |
dc.identifier.cristin | 1954772 | |
dc.source.journal | Clinical Trials | en_US |
dc.identifier.citation | Clinical Trials. 2022, 19(1), 116-118. | en_US |
dc.source.volume | 19 | en_US |
dc.source.issue | 1 | en_US |