Vegan diet and bone health—results from the cross-sectional RBVD study
dc.contributor.author | Menzel, Juliane | |
dc.contributor.author | Abraham, Klaus | |
dc.contributor.author | Stangl, Gabriele I. | |
dc.contributor.author | Ueland, Per Magne | |
dc.contributor.author | Obeid, Rima | |
dc.contributor.author | Schulze, Matthias B. | |
dc.contributor.author | Herter-Aeberli, Isabelle | |
dc.contributor.author | Schwerdtle, Tanja | |
dc.contributor.author | Weikert, Cornelia | |
dc.date.accessioned | 2022-04-21T08:24:22Z | |
dc.date.available | 2022-04-21T08:24:22Z | |
dc.date.created | 2022-01-18T14:32:06Z | |
dc.date.issued | 2021 | |
dc.identifier.issn | 2072-6643 | |
dc.identifier.uri | https://hdl.handle.net/11250/2991845 | |
dc.description.abstract | Scientific evidence suggests that a vegan diet might be associated with impaired bone health. Therefore, a cross-sectional study (n = 36 vegans, n = 36 omnivores) was used to investigate the associations of veganism with calcaneal quantitative ultrasound (QUS) measurements, along with the investigation of differences in the concentrations of nutrition- and bone-related biomarkers between vegans and omnivores. This study revealed lower levels in the QUS parameters in vegans compared to omnivores, e.g., broadband ultrasound attenuation (vegans: 111.8 ± 10.7 dB/MHz, omnivores: 118.0 ± 10.8 dB/MHz, p = 0.02). Vegans had lower levels of vitamin A, B2, lysine, zinc, selenoprotein P, n-3 fatty acids, urinary iodine, and calcium levels, while the concentrations of vitamin K1, folate, and glutamine were higher in vegans compared to omnivores. Applying a reduced rank regression, 12 out of the 28 biomarkers were identified to contribute most to bone health, i.e., lysine, urinary iodine, thyroid-stimulating hormone, selenoprotein P, vitamin A, leucine, α-klotho, n-3 fatty acids, urinary calcium/magnesium, vitamin B6, and FGF23. All QUS parameters increased across the tertiles of the pattern score. The study provides evidence of lower bone health in vegans compared to omnivores, additionally revealing a combination of nutrition-related biomarkers, which may contribute to bone health. Further studies are needed to confirm these findings. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | MDPI | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Vegan diet and bone health—results from the cross-sectional RBVD study | en_US |
dc.type | Journal article | en_US |
dc.type | Peer reviewed | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2021 The Author(s) | en_US |
dc.source.articlenumber | 685 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.doi | 10.3390/nu13020685 | |
dc.identifier.cristin | 1983722 | |
dc.source.journal | Nutrients | en_US |
dc.identifier.citation | Nutrients. 2021, 13 (2), 685. | en_US |
dc.source.volume | 13 | en_US |
dc.source.issue | 2 | en_US |
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