dc.contributor.author | Fjelltveit, Elisabeth Berg | |
dc.contributor.author | Brokstad, Rebecca Jane Cox | |
dc.contributor.author | Østensjø, Jørgen | |
dc.contributor.author | Blomberg, Bjørn | |
dc.contributor.author | Ebbesen, Marit Helen | |
dc.contributor.author | Langeland, Nina | |
dc.contributor.author | Mohn, Kristin Greve Isdahl | |
dc.date.accessioned | 2022-11-16T06:52:08Z | |
dc.date.available | 2022-11-16T06:52:08Z | |
dc.date.created | 2021-01-22T16:07:46Z | |
dc.date.issued | 2022 | |
dc.identifier.issn | 0022-1899 | |
dc.identifier.uri | https://hdl.handle.net/11250/3032009 | |
dc.description.abstract | Background
Influenza is difficult to distinguish clinically from other acute respiratory infections. Rapid laboratory diagnosis can help initiate early effective antiviral treatment and isolation. Implementing a novel point-of-care test (POCT) for influenza in the emergency department (ED) could improve treatment and isolation strategies and reduce the length of stay (LOS).
Methods
In a prospective, controlled observational cohort study, we enrolled patients admitted due to acute respiratory illness to 2 public hospitals in Bergen, Norway, one using a rapid POCT for influenza (n = 400), the other (n = 167) using conventional rapid laboratory-based assay.
Results
Prevalence of influenza was similar in the 2 hospitals (154/400, 38% vs 38%, 63/167; P = .863). Most patients in both hospitals received antiviral (83% vs 81%; P = .703) and antibiotic treatment (72% vs 62%; P = .149). Isolation was more often initiated in ED in the hospital using POCT (91% vs 80%; P = .025). Diagnosis by POCT was associated with shorter hospital stay; old age, diabetes, cancer, and use of antibiotics, particularly broad-spectrum antibiotics, were associated with prolonged stay.
Conclusions
POCT implementation in ED resulted in improved targeted isolation and shorter LOS. Regardless of POCT use, most influenza patients received antivirals (>80%) and antibiotics (>69%). | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Oxford University Press | en_US |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.no | * |
dc.title | Point-of-care influenza testing impacts clinical decision, patient flow and length of stay in hospitalized adults | en_US |
dc.type | Journal article | en_US |
dc.type | Peer reviewed | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2020 The Author(s) | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 2 | |
dc.identifier.doi | 10.1093/infdis/jiaa690 | |
dc.identifier.cristin | 1877414 | |
dc.source.journal | Journal of Infectious Diseases | en_US |
dc.source.pagenumber | 97-108 | en_US |
dc.identifier.citation | Journal of Infectious Diseases. 2022, 226, 97-108. | en_US |
dc.source.volume | 226 | en_US |