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dc.contributor.authorSharashova, Ekaterina
dc.contributor.authorGerdts, Eva
dc.contributor.authorBall, Jocasta
dc.contributor.authorEspnes, Hilde
dc.contributor.authorJacobsen, Bjarne K.
dc.contributor.authorKildal, Simon
dc.contributor.authorMathiesen, Ellisiv B.
dc.contributor.authorNjølstad, Inger
dc.contributor.authorRosengren, Annika
dc.contributor.authorSchirmer, Henrik
dc.contributor.authorWilsgaard, Tom
dc.contributor.authorLøchen, Maja-Lisa
dc.description.abstractAims To explore sex-specific time trends in atrial fibrillation (AF) incidence and to estimate the impact of changes in risk factor levels using individual participant-level data from the population-based Tromsø Study 1994–2016. Methods and results A total of 14 818 women and 13 225 men aged 25 years or older without AF were enrolled in the Tromsø Study between 1994 and 2008 and followed up for incident AF throughout 2016. Poisson regression was used for statistical analyses. During follow-up, age-adjusted AF incidence rates in women decreased from 1.19 to 0.71 per 1000 person-years. In men, AF incidence increased from 1.18 to 2.82 per 1000 person-years in 2004, and then declined to 1.94 per 1000 person-years in 2016. Changes in systolic blood pressure (SBP) and diastolic blood pressure (DBP), body mass index (BMI), physical activity, smoking and alcohol consumption together accounted for 10.9% [95% confidence interval (CI): −2.4 to 28.6] of the AF incidence decline in women and for 44.7% (95% CI: 19.2; 100.0) of the AF incidence increase in men. Reduction in SBP and DBP had the largest contribution to the decrease in AF incidence in women. Increase in BMI had the largest contribution to the increase in AF incidence in men. Conclusion In the population-based Tromsø Study 1994–2016, AF incidence decreased in women and increased following a reverse U-shape in men. Individual changes in SBP and DBP in women and individual changes in BMI in men were the most important risk factors contributing to the AF incidence trends.en_US
dc.publisherOxford University Pressen_US
dc.rightsNavngivelse-Ikkekommersiell 4.0 Internasjonal*
dc.titleSex-specific time trends in incident atrial fibrillation and the contribution of risk factors: the Tromsø Study 1994–2016en_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.rights.holderCopyright The Author(s) 2022en_US
dc.source.journalEuropean Journal of Preventive Cardiology (EJPC)en_US
dc.identifier.citationEuropean Journal of Preventive Cardiology. 2023, 30 (1), 72–81.en_US

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Navngivelse-Ikkekommersiell 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse-Ikkekommersiell 4.0 Internasjonal