dc.contributor.author | Kantomaa, Marko T. | |
dc.contributor.author | Tolvanen, Mimmi | |
dc.contributor.author | Halonen, Miia | |
dc.contributor.author | Svanes, Cecilie | |
dc.contributor.author | Järvelin, Marjo-Riitta | |
dc.contributor.author | Sebert, Sylvain | |
dc.date.accessioned | 2024-03-19T10:14:09Z | |
dc.date.available | 2024-03-19T10:14:09Z | |
dc.date.created | 2023-03-03T13:07:59Z | |
dc.date.issued | 2023 | |
dc.identifier.issn | 1661-7827 | |
dc.identifier.uri | https://hdl.handle.net/11250/3123063 | |
dc.description.abstract | We investigated the influence of a farming environment on asthma at three time points from birth to 46 years using the Northern Finland Birth Cohort 1966 (n = 10,926). The prevalence of asthma was investigated by postal questionnaires at 14, 31 and 46 years of age. Exposure to a farming environment was assessed by a postal questionnaire at birth and at 31 and 46 years of age. Odds ratios (ORs) and their 95% confidence intervals (95% CIs) for the prevalence of asthma were obtained from multinomial logistic regression, stratified by sex. Being born in a farmer family was potentially causally associated with lower risk of asthma in males at 31 years of age (OR 0.56, 95% CI 0.37, 0.85) and in females at 46 years of age (OR 0.64, 95% CI 0.44, 0.95). Working as a farmer was not associated with asthma. Exposure to a farming environment in childhood may have a lifelong impact on developing asthma from birth through young adulthood and until middle age, indicating that ‘immune deviation’ may persist throughout life. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | MDPI | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Influence of farm environment on asthma during the life course: A population-based birth cohort study in northern Finland | en_US |
dc.type | Journal article | en_US |
dc.type | Peer reviewed | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2023 The Author(s) | en_US |
dc.source.articlenumber | 2128 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.doi | 10.3390/ijerph20032128 | |
dc.identifier.cristin | 2131014 | |
dc.source.journal | International Journal of Environmental Research and Public Health (IJERPH) | en_US |
dc.identifier.citation | International Journal of Environmental Research and Public Health (IJERPH). 2023, 20 (3), 2128. | en_US |
dc.source.volume | 20 | en_US |
dc.source.issue | 3 | en_US |