Periodontitis is associated with airflow obstruction in the Malmö Offspring Dental Study
Røsland, Anders; Bertelsen, Randi Jacobsen; Bunæs, Dagmar Fosså; Drengenes, Christine; Engström, Gunnar; Klinge, Bjørn; Lie, Stein Atle; Nilsson, Peter M.; Jönsson, Daniel; Malinovschi, Andrei
Journal article, Peer reviewed
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Date
2024Metadata
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Abstract
Aim
To investigate the association between periodontitis and lung function in the Malmö Offspring Dental Study.
Materials and Methods
In all 1001 individuals (49.9% female, mean age: 44.6) from Malmö Offspring Dental Study were included. Periodontitis was assessed by a full-mouth examination protocol including bleeding on probing and classified according to the American Academy of Periodontology/Center for Disease Control definitions. Forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) were expressed as absolute values and %predicted according to Global Lung Function Initiative reference values. FEV1, FVC and FEV1/FVC were analysed in relation to periodontal status using linear regression.
Results
Severe periodontitis was found in 7% of the population. Adjusted regression models showed significant associations between lung function and severe periodontitis with 2.1 unit lower FEV1/FVC ratio (95% CI: −3.91, –0.23) and odds ratio (adjusted) of 2.56 (95% CI: 1.40, 4.75, p = .003) for airflow obstruction (FEV1/FVC less than the lower limit of normal) if having severe periodontitis. Lower values of %predicted FEV1 and %predicted FVC, but not FEV1/FVC, were found in individuals with >25% bleeding on probing.
Conclusions
Severe periodontitis was associated with lower FEV1/FVC ratio and airflow obstruction in the present cohort. More large-scale prospective studies and intervention studies are required for a comprehensive evaluation.