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Model-based exploration of hypokalemia in dairy cows
(Journal article; Peer reviewed, 2022)Hypokalemia in dairy cows, which is characterized by too low serum potassium levels, is a severe mineral disorder that can be life threatening. In this paper, we explore different originating conditions of hypokalemia—reduced ... -
Model-based exploration of the impact of glucose metabolism on the estrous cycle dynamics in dairy cows
(Peer reviewed; Journal article, 2020)Background: Nutrition plays a crucial role in regulating reproductive hormones and follicular development in cattle. This is visible particularly during the time of negative energy balance at the onset of milk production ... -
Model-based Visualization for Medical Education and Training
(Peer reviewed; Journal article, 2019)Anatomy, or the study of the structure of the human body, is an essential component of medical education. Certain parts of human anatomy are considered to be more complex to understand than others, due to a multitude of ... -
Model-Driven Automatic Question Generation for a Gamified Clinical Guideline Training System
(Journal article; Peer reviewed, 2020)Clinical practice guidelines (CPGs) are a cornerstone of modern medical practice since they summarize the vast medical literature and provide care recommendations based on the current best evidence. However, there are ... -
Modeling and simulating the sample complexity of solving LWE using BKW-style algorithms
(Journal article; Peer reviewed, 2022)The Learning with Errors (LWE) problem receives much attention in cryptography, mainly due to its fundamental significance in post-quantum cryptography. Among its solving algorithms, the Blum-Kalai-Wasserman (BKW) algorithm, ... -
Modeling of Multivalent Ligand-Receptor Binding Measured by kinITC
(Peer reviewed; Journal article, 2019)In addition to the conventional Isothermal Titration Calorimetry (ITC), kinetic ITC (kinITC) not only gains thermodynamic information, but also kinetic data from a biochemical binding process. Moreover, kinITC gives insights ... -
Modelling migration patterns of fish using depth and temperature preferences
(Master thesis, 2012-04-27)Time series of depth and temperature derived from electronic tagging of fish have been used to construct a stochastic model that aims at capturing main characteristics of the observations. Mixed Ornstein-Uhlenbeck process ... -
Modelling Oscillatory Patterns in the Bovine Estrous Cycle with Boolean Delay Equations
(Journal article; Peer reviewed, 2021)Boolean delay equations (BDEs), with their relatively simple and intuitive mode of modelling, have been used in many research areas including, for example, climate dynamics and earthquake propagation. Their application to ... -
Modelling overfow using mixed integer programming in short‑term hydropower scheduling
(Journal article; Peer reviewed, 2023)Short-term hydropower scheduling seeks to find a production schedule that maximizes profit, but must also consider the hydrological balance and risk of overflow. Overflow is by nature a non-linear and non-convex phenomenon. ... -
Modelling the structure, function and evolution of Polycomb/Trithorax Response Elements
(Doctoral thesis, 2020-11-20)The correct development of animals and plants depends on carefully coordinated gene regulation. Polycomb/Trithorax Group (PcG/TrxG) proteins are conserved epigenetic regulators that are recruited to Polycomb/Trithorax ... -
Models and Solution Methods for the Pooling Problem
(Doctoral thesis, 2012-06-18)Pipeline transportation of natural gas is largely affected by restrictions regarding gas quality imposed by the market and the actual quality of the gas produced at sources. From the sources, gas flow streams of unequal ... -
Modification to planarity is fixed parameter tractable
(Peer reviewed; Journal article, 2019)A replacement action is a function L that maps each k-vertex labeled graph to another k-vertex graph. We consider a general family of graph modification problems, called L-Replacement to C, where the input is a graph G and ... -
Modulation of Transcriptional and Inflammatory Responses in Murine Macrophages by the Mycobacterium tuberculosis Mammalian Cell Entry (Mce) 1 Complex
(Peer reviewed; Journal article, 2011-10-24)The outcome of many infections depends on the initial interactions between agent and host. Aiming at elucidating the effect of the M. tuberculosis Mce1 protein complex on host transcriptional and immunological responses ... -
Molecular mechanisms of adaptation emerging from the physics and evolution of nucleic acids and proteins
(Peer reviewed; Journal article, 2014)DNA, RNA and proteins are major biological macromolecules that coevolve and adapt to environments as components of one highly interconnected system. We explore here sequence/structure determinants of mechanisms of adaptation ... -
Monte Carlo Simulations in Cost Estimation Analysis
(Master thesis, 2024-06-03) -
Monte Carlo Study of the Formation and Conformational Properties of Dimers of Aβ42 Variants
(Peer reviewed; Journal article, 2011)Small soluble oligomers, and dimers in particular, of the amyloid β-peptide (Aβ) are believed to play an important pathological role in Alzheimer's disease. Here, we investigate the spontaneous dimerization of Aβ42, with ... -
More Applications of the d-Neighbor Equivalence: Acyclicity and Connectivity Constraints
(Journal article; Peer reviewed, 2021)In this paper, we design a framework to obtain efficient algorithms for several problems with a global constraint (acyclicity or connectivity) such as Connected Dominating Set, Node Weighted Steiner Tree, Maximum Induced ... -
Mostar index and edge Mostar index of polymers
(Journal article; Peer reviewed, 2021)Let G=(V,E) be a graph and e=uv∈E. Define nu(e,G) be the number of vertices of G closer to u than to v. The number nv(e,G) can be defined in an analogous way. The Mostar index of G is a new graph invariant defined as ... -
MPCC: Strong stability of M-stationary points
(Journal article; Peer reviewed, 2021)In this paper we study the class of mathematical programs with complementarity constraints MPCC. Under the Linear Independence constraint qualification MPCC-LICQ we state a topological as well as an equivalent algebraic ... -
Multi-GPU Rendering with Vulkan API
(Master thesis, 2018-08-21)Vulkan API provides a low level interface to modern Graphics Processing Units (GPUs). With this thesis, we demonstrate how to use Vulkan to send commands explicitly to separate GPUs for implementing platform- and vendor ...