dc.contributor.author | Persson, Robert | en_US |
dc.contributor.author | Wensaas, Knut-Arne | en_US |
dc.contributor.author | Hanevik, Kurt | en_US |
dc.contributor.author | Eide, Geir Egil | en_US |
dc.contributor.author | Langeland, Nina | en_US |
dc.contributor.author | Rørtveit, Guri | en_US |
dc.date.accessioned | 2016-01-11T11:28:06Z | |
dc.date.available | 2016-01-11T11:28:06Z | |
dc.date.issued | 2015-06-10 | |
dc.Published | BMC Gastroenterology 2015, 15(1) | eng |
dc.identifier.issn | 1471-230X | |
dc.identifier.uri | https://hdl.handle.net/1956/10919 | |
dc.description.abstract | BACKGROUND: To investigate in a cohort with previous gastrointestinal infection and a control group the prevalence of overactive bladder syndrome (OAB), and how it was associated with three other functional disorders; irritable bowel syndrome (IBS), functional dyspepsia (FD) and chronic fatigue (CF). METHODS: Controlled historic cohort study including 724 individuals with laboratory confirmed giardiasis six years earlier, and 847 controls matched by gender and age. Prevalence and odds ratios (OR) with 95 % confidence intervals (CI) were calculated. RESULTS: The prevalence of OAB was 18.7 % (134/716) in the exposed group and 13.6 % (113/833) in the control group (p = 0.007). The association between OAB and IBS was strong in the control group (OR: 2.42; 95 % CI: 1.45 to 4.04), but insignificant in the Giardia exposed (OR: 1.29; 95 % CI: 0.88 to 1.88). The association between OAB and FD was weak in both groups. CF was strongly associated with OAB (OR: 2.73; 95 % CI: 1.85 to 4.02 in the exposed and OR: 2.79; 95 % CI: 1.69 to 4.62 in the controls), and this association remained when comorbid conditions were excluded. CONCLUSIONS: Sporadic IBS was associated with increased risk of OAB, whereas post-infectious IBS was not. An apparent association between OAB and previous Giardia infection can be ascribed to comorbid functional disorders. | en_US |
dc.language.iso | eng | eng |
dc.publisher | BioMed Central | eng |
dc.rights | Attribution CC BY 4.0 | eng |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | eng |
dc.subject | Giardia lamblia | eng |
dc.subject | Irritable bowel syndrome | eng |
dc.subject | Dyspepsia | eng |
dc.subject | Urinary bladder | eng |
dc.subject | Co-morbidity | eng |
dc.title | The relationship between irritable bowel syndrome, functional dyspepsia, chronic fatigue and overactive bladder syndrome: A controlled study 6 years after acute gastrointestinal infection | en_US |
dc.type | Peer reviewed | |
dc.type | Journal article | |
dc.date.updated | 2015-11-09T09:18:16Z | |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright Persson et al. 2015 | |
dc.identifier.doi | https://doi.org/10.1186/s12876-015-0296-0 | |
dc.identifier.cristin | 1265704 | |
dc.subject.nsi | VDP::Medisinske Fag: 700 | en_US |