SearchGUI: a highly adaptable common interface for proteomics search and de novo engines
Peer reviewed, Journal article
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Original versionBarsnes H, Vaudel M. SearchGUI: a highly adaptable common interface for proteomics search and de novo engines. Journal of Proteome Research. 2018;17(7):2552-2555 https://doi.org/10.1021/acs.jproteome.8b00175
Mass-spectrometry-based proteomics has become the standard approach for identifying and quantifying proteins. A vital step consists of analyzing experimentally generated mass spectra to identify the underlying peptide sequences for later mapping to the originating proteins. We here present the latest developments in SearchGUI, a common open-source interface for the most frequently used freely available proteomics search and de novo engines that has evolved into a central component in numerous bioinformatics workflows.