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dc.contributor.authorGuldbrandsen, Astriden_US
dc.contributor.authorFarag, Yehia Mohamed Mokhtaren_US
dc.contributor.authorLereim, Ragnhild Reehorsten_US
dc.contributor.authorBerven, Frodeen_US
dc.contributor.authorBarsnes, Haralden_US
dc.date.accessioned2020-06-18T11:55:21Z
dc.date.available2020-06-18T11:55:21Z
dc.date.issued2019
dc.PublishedGuldbrandsen A, Farag YMM, Lereim RR, Berven F, Barsnes H. Essential Features and Use Cases of the Cerebrospinal Fluid Proteome Resource (CSF-PR). Methods in molecular biology. 2019;2044:377-391eng
dc.identifier.issn1064-3745
dc.identifier.issn1940-6029
dc.identifier.urihttps://hdl.handle.net/1956/22711
dc.descriptionUnder embargo until: 2020-08-21en_US
dc.description.abstractEvery year, a large number of published studies present biomarkers for various neurological disorders. Many of these studies are based on mass spectrometry proteomics data and describe comparison of the abundance of proteins in cerebrospinal fluid between two or more disease groups. As the number of such studies is growing, it is no longer straightforward to obtain an overview of which specific proteins are increased or decreased between the numerous relevant diseases and their many subcategories, or to see the larger picture or trends between related diseases. To alleviate this situation, we therefore mined the literature for mass spectrometry–based proteomics studies including quantitative protein data from cerebrospinal fluid of patients with multiple sclerosis, Alzheimer’s disease, and Parkinson’s disease and organized the extracted data in the Cerebrospinal Fluid Proteome Resource (CSF-PR). CSF-PR is freely available online at http://probe.uib.no/csf-pr, is highly interactive, and allows for easy navigation, visualization, and export of the published scientific data. This chapter will guide the user through some of the most important features of the tool and show examples of the suggested use cases.en_US
dc.language.isoengeng
dc.publisherSpringereng
dc.titleEssential Features and Use Cases of the Cerebrospinal Fluid Proteome Resource (CSF-PR)en_US
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2019-11-11T14:57:08Z
dc.description.versionacceptedVersionen_US
dc.rights.holderCopyright Springer Science+Business Media, LLC, part of Springer Nature 2019
dc.identifier.doihttps://doi.org/10.1007/978-1-4939-9706-0_25
dc.identifier.cristin1723772
dc.source.journalMethods in molecular biology
dc.relation.projectBergens forskningsstiftelse: BFS2016REK02
dc.relation.projectNorges forskningsråd: 251235


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