Browsing Department of Clinical Science by Journals "Frontiers in Cell and Developmental Biology"
Now showing items 1-3 of 3
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In vivo environment swiftly restricts human pancreatic progenitors toward mono-hormonal identity via a HNF1A/HNF4A mechanism
(Journal article; Peer reviewed, 2020)Generating insulin-producing β-cells from human induced pluripotent stem cells is a promising cell replacement therapy for improving or curing insulin-dependent diabetes. The transplantation of end-stages differentiating ... -
The neutral amino acid transporter SLC7A10 in adipose tissue, obesity and insulin resistance
(Journal article; Peer reviewed, 2022)Obesity, insulin resistance and type 2 diabetes represent major global health challenges, and a better mechanistic understanding of the altered metabolism in these conditions may give improved treatment strategies. SLC7A10, ... -
Starvation to Glucose Reprograms Development of Neurovascular Unit in Embryonic Retinal Cells
(Journal article; Peer reviewed, 2021)Perinatal exposure to starvation is a risk factor for development of severe retinopathy in adult patients with diabetes. However, the underlying mechanisms are not completely understood. In the present study, we shed light ...