Blar i Department of Clinical Science på tidsskrift "Translational psychiatry"
Viser treff 1-7 av 7
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Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder
(Peer reviewed; Journal article, 2019-10-17)Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable common childhood-onset neurodevelopmental disorder. Some rare copy number variations (CNVs) affect multiple neurodevelopmental disorders such as ... -
Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder
(Peer reviewed; Journal article, 2018)Ankyrin-3 (ANK3) is one of the few genes that have been consistently identified as associated with bipolar disorder by multiple genome-wide association studies. However, the exact molecular basis of the association remains ... -
Exome chip analyses in adult attention deficit hyperactivity disorder
(Peer reviewed; Journal article, 2016)Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable childhood-onset neuropsychiatric condition, often persisting into adulthood. The genetic architecture of ADHD, particularly in adults, is largely unknown. ... -
Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder
(Peer reviewed; Journal article, 2018)The Wnt signaling pathway plays a crucial role in neurodevelopment and in regulating the function and structure of the adult nervous system. Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental disorders with ... -
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
(Peer reviewed; Journal article, 2017-06-20)Borderline personality disorder (BOR) is determined by environmental and genetic factors, and characterized by affective instability and impulsivity, diagnostic symptoms also observed in manic phases of bipolar disorder ... -
Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins
(Peer reviewed; Journal article, 2014)Differences in general cognitive ability (intelligence) account for approximately half of the variation in any large battery of cognitive tests and are predictive of important life events including health. Genome-wide ... -
Williams Syndrome neuroanatomical score associates with GTF2IRD1 in large-scale magnetic resonance imaging cohorts: A proof of concept for multivariate endophenotypes
(Peer reviewed; Journal article, 2018-06-08)Despite great interest in using magnetic resonance imaging (MRI) for studying the effects of genes on brain structure in humans, current approaches have focused almost entirely on predefined regions of interest and had ...