• Cabozantinib is effective in melanoma brain metastasis cell lines and affects key signaling pathways 

      Mannsåker, Trond Are; Hoang, Tuyen; Aasen, Synnøve Nymark; Bjørnstad, Ole Vidhammer; Parajuli, Himalaya; Sundstrøm, Terje; Thorsen, Frits (Journal article; Peer reviewed, 2021-11-14)
      Melanomas have a high potential to metastasize to the brain. Recent advances in targeted therapies and immunotherapies have changed the therapeutical landscape of extracranial melanomas. However, few patients with melanoma ...
    • CCT196969 effectively inhibits growth and survival of melanoma brain metastasis cells 

      Reigstad, Agathe; Herdlevær, Christina Frantzen; Rigg, Emma Kayleigh; Hoang, Tuyen; Bjørnstad, Ole Vidhammer; Aasen, Synnøve Nymark; Preis, Jasmin; Haan, Claude; Sundstrøm, Terje; Thorsen, Frits (Journal article; Peer reviewed, 2022)
      Melanomas frequently metastasize to the brain. Despite recent progress in the treatment of melanoma brain metastasis, therapy resistance and relapse of disease remain unsolved challenges. CCT196969 is a SRC family kinase ...