Blar i Department of Biomedicine på forfatter "Eriksson, Inger"
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A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation
Missaghian, Parisa; Dierker, Tabea; Khosrowabadi, Elham; Axling, Fredrik; Eriksson, Inger; Ghanem, Abdurrahman; Gullberg, Marion Kusche; Kellokumpu, Sakari; Kjellén, Lena (Journal article; Peer reviewed, 2022)NDST1 (glucosaminyl N-deacetylase/N-sulfotransferase) is a key enzyme in heparan sulfate (HS) biosynthesis, where it is responsible for HS N-deacetylation and N-sulfation. In addition to the full length human enzyme of 882 ...