Blar i Department of Biomedicine på forfatter "Obeïd, Patricia"

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    • Mechanical stress shapes the cancer cell response to neddylation inhibition 

      Mittler, Frédérique; Obeïd, Patricia; Haguet, Vincent; Allier, Cédric; Gerbaud, Sophie; Rulina, Anastasiia; Gidrol, Xavier; Balakirev, Maxim Y. (Journal article; Peer reviewed, 2022)
      Background The inhibition of neddylation by the preclinical drug MLN4924 represents a new strategy to combat cancer. However, despite being effective against hematologic malignancies, its success in solid tumors, where ...