Browsing Department of Biomedicine by Subject "Neuroepigenetics"

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Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo.

Maag, Jesper L.V.; Kaczorowski, Dominik C.; Panja, Debabrata; Peters, Timothy J.; Bramham, Clive R.; Wibrand, Karin; Dinger, Marcel E. (Peer reviewed; Journal article, 2017-03-23)

Background: DNA methylation is a key modulator of gene expression in mammalian development and cellular differentiation, including neurons. To date, the role of DNA modifications in long-term potentiation (LTP) has not ...