Blar i Department of Clinical Medicine på forfatter "Søreide, Kjetil"
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Development and clinical implementation of a structured, simulation-based training programme in laparoscopic appendectomy: Description, validation and evaluation
Skjold-Ødegaard, Benedicte; Ersdal, Hege Langli; Assmus, Jörg; Nedrebø, Bjørn Steinar Olden; Sjo, Ole; Søreide, Kjetil (Journal article; Peer reviewed, 2021)Background: Laparoscopic appendectomy is a common procedure in general surgery but is likely underused in structured and real-life teaching. This study describes the development, validation and evaluation of implementing ... -
The diagnostic differentiation challenge in acute appendicitis: How to distinguish between uncomplicated and complicated appendicitis in adults
Skjold-Ødegaard, Benedicte; Søreide, Kjetil (Journal article; Peer reviewed, 2022-07-15)Background: How to best define, diagnose and differentiate uncomplicated from complicated acute appendicitis remains debated. Hence, the aim of this review was to present an overview of the current knowledge and emerging ... -
Digital Image Analysis of the Proliferation Markers Ki67 and Phosphohistone H3 in Gastroenteropancreatic Neuroendocrine Neoplasms: Accuracy of Grading Compared with Routine Manual Hot Spot Evaluation of the Ki67 Index
Lea, Dordi; Gudlaugsson, Einar G.; Skaland, Ivar; Lillesand, Melinda; Søreide, Kjetil; Søreide, Jon A. (Journal article; Peer reviewed, 2021)Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are rare epithelial neoplasms. Grading is based on mitotic activity or the percentage of Ki67-positive cells in a hot spot. Routine methods have poor intraobserver ... -
E-AHPBA-ESSO-ESSR Innsbruck consensus guidelines for preoperative liver function assessment before hepatectomy
Primavesi, Florian; Maglione, Manuel; Cipriani, Federica; Denecke, Timm; Oberkofler, Christian E; Starlinger, Patrick; Dasari, Bobby V. M; Heil, Jan; Sgarbura, Olivia; Søreide, Kjetil; Diaz-Nieto, Rafael; Fondevila, Constantino; Frampton, Adam E.; Geisel, Dominik; Henninger, Benjamin; Hessheimer, Amelia J; Lesurtel, Mickaël; Mole, Damian; Öllinger, Robert; Olthof, Pim; Reiberger, Thomas; Schnitzbauer, Andreas A; Schwarz, Christoph; Sparrelid, Ernesto; Stockmann, Martin; Truant, StCrossed D sign©phanie; Aldrighetti, Luca; Braunwarth, Eva; D'hondt, Mathieu; Deoliveira, Michelle L; Erdmann, Joris; Fuks, David; Gruenberger, Thomas; Kaczirek, Klaus; Malik, Hassan; Öfner, Dietmar; Rahbari, Nuh N; Göbel, Georg; Siriwardena, Ajith K; Stättner, Stefan (Journal article; Peer reviewed, 2023)Background Posthepatectomy liver failure (PHLF) contributes significantly to morbidity and mortality after liver surgery. Standardized assessment of preoperative liver function is crucial to identify patients at risk. ... -
Early Diagnosis of Pancreatic Cancer: Clinical Premonitions, Timely Precursor Detection and Increased Curative-Intent Surgery
Søreide, Kjetil; Ismail, Warsan; Roalsø, Marcus Thomas Thor; Ghotbi, Jacob; Zaharia, Claudia (Journal article; Peer reviewed, 2023)Background: The overall poor prognosis in pancreatic cancer is related to late clinical detection. Early diagnosis remains a considerable challenge in pancreatic cancer. Unfortunately, the onset of clinical symptoms in ... -
Editorial: facts, figures and the future
Søreide, Kjetil (Peer reviewed; Journal article, 2015-01-09) -
Effect of Perioperative Dexamethasone and Different NSAIDs on Anastomotic Leak Risk: A Propensity Score Analysis
Rushfeldt, Christian; Agledahl, Uwe; Sveinbjørnsson, Baldur; Søreide, Kjetil; Wilsgaard, Tom (Peer reviewed; Journal article, 2016-11)Background: Perioperative use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with risk of anastomotic leak (AL). However, concomitant use of other drugs could infer a bias in risk assessment. Thus, we aimed ... -
Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries
Glasbey, James C; Abbott, Tom EF; Ademuyiwa, Adesoji; Adisa, Adewale; Alameer, Ehab; Alshryda, Sattar; Augestad, Knut Magne; Søreide, Kjetil; Singh, Banipal Gurpreet; Arnaud, Alexis P; Bankhead-Kendall, B.; Abou Chaar, MK; Chaudhry, Daoud; Costas-Chavarri, Ainhoa; Cunha, MF; Davies, Justine I; Desai, A.; Elhadi, Muhammed; Fiore, Marco; Fitzgerald, J. Edward; Fourtounas, M.; Fowler, Alex James; Futaba, Kay; Gallo, Gaetano; Ghosh, Dhruva; Gujjuri, RR; Hamilton, Rebecca; Haque, Parvez; Harrison, Ewen M.; Hutchinson, Peter; Hyman, Gabriella; Isik, Arda; Jayarajah, Umesh; Kaafarani, Haytham MA; Kadir, Bryar; Lawani, Ismail; Lederhuber, Hans; Li, Elizabeth; Löffler, Markus W; Lorena, Maria Aguilera; Mann, Harvinder; Martin, Janet; Mazingi, Dennis; McClain, Craig D.; McLean, Kenneth A; Meara, John G.; Ramos-De la Medina, Antonio; Mengesha, Mengistu; Minaya, Ana; Modolo, Maria Marta; Moore, Rachel (Journal article; Peer reviewed, 2022)Background The 2015 Lancet Commission on global surgery identified surgery and anaesthesia as indispensable parts of holistic health-care systems. However, COVID-19 exposed the fragility of planned surgical services around ... -
Elevated microsatellite alterations at selected tetranucleotides (EMAST) is not attributed to MSH3 loss in stage I-III colon cancer: An automated, digitalized assessment by immunohistochemistry of whole slides and hot spots
Watson, Martin M; Lea, Dordi; Hagland, Hanne Røland; Søreide, Kjetil (Peer reviewed; Journal article, 2019-12)INTRODUCTION: EMAST is a poorly understood form of microsatellite instability (MSI) in colorectal cancer (CRC) for which loss of MSH3 has been proposed as the underlying mechanism, based on experimental studies. We aimed ... -
Elevated microsatellite alterations at selected tetranucleotides in early-stage colorectal cancers with and without high-frequency microsatellite instability: same, same but different?
Watson, Martin M; Lea, Dordi; Rewcastle, Emma; Hagland, Hanne Røland; Søreide, Kjetil (Peer reviewed; Journal article, 2016-07)Microsatellite instability (MSI) is associated with better prognosis in colorectal cancer (CRC). Elevated microsatellite alterations at selected tetranucleotides (EMAST) is a less-understood form of MSI. Here, we aim to ... -
Emergency resuscitative thoracotomy performed in European civilian trauma patients with blunt or penetrating injuries: a systematic review
Narvestad, Jon; Meskinfamfard, M.; Søreide, Kjetil (Peer reviewed; Journal article, 2015)Purpose: Emergency resuscitative thoracotomy (ERT) is a lifesaving procedure in selected patients. Indications are still being debated, but outcome in blunt trauma is believed to be poor. Recent reports from European ... -
Emergency surgery in the elderly: the balance between function, frailty, fatality and futility
Søreide, Kjetil; Desserud, Kari F. (Peer reviewed; Journal article, 2015-02-03)Becoming old is considered a privilege and results from the socioeconomic progress and improvements in health care systems worldwide. However, morbidity and mortality increases with age, and even more so in acute onset ... -
Emerging Role of Epigenetic Alterations as Biomarkers and Novel Targets for Treatments in Pancreatic Ductal Adenocarcinoma
Roalsø, Marcus Thomas Thor; Hald, Øyvind; Alexeeva, Marina; Søreide, Kjetil (Journal article; Peer reviewed, 2022)Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with limited treatment options. Emerging evidence shows that epigenetic alterations are present in PDAC. The changes are potentially reversible and therefore ... -
Epidemiology and classification of gastroenteropancreatic neuroendocrine neoplasms using current coding criteria
Sandvik, Oddvar Mathias; Søreide, Kjetil; Gudlaugsson, Einar; Kvaløy, Jan Terje; Søreide, Jon Arne (Peer reviewed; Journal article, 2016-02)Background: The lack of uniform criteria for coding of gastroenteropancreatic neuroendocrine neoplasia (GEP-NEN) has hampered previous epidemiological studies. The epidemiology of GEP-NEN was investigated in this study ... -
Epidemiology of abdominal trauma: An age- and sex-adjusted incidence analysis with mortality patterns
Larsen, Johannes Wiik; Søreide, Kjetil; Søreide, Jon Arne; Tjosevik, Kjell E; Kvaløy, Jan Terje; Thorsen, Kenneth (Journal article; Peer reviewed, 2022)Purpose Abdominal injuries may occur in up to one-third of all patients who suffer severe trauma, but little is known about epidemiological trends and characteristics in a Northern European setting. This study investigated ... -
The ESSO core curriculum committee update on surgical oncology
van der Hage, Jos; Sandrucci, Sergio; Audisio, Riccardo; Wyld, Lynda; Søreide, Kjetil; Amaral, Teresa; Bahadoer, Viren; Beets, Geerard; Benstead, Kim; Nilsen, Elisabeth Berge; Bol, Kalijn; Brandl, Andreas; Braun, Jerry; Cufer, Tanja; Dopazo, Cristina; Edhemovic, Ibrahim; Eriksen, Jesper Grau; Fiore, Marco; van Ginhoven, Tessa; Gonzalez-Moreno, Santiago; Hutteman, Merlijn; Masannat, Yazan; Onesti, Elisa Concetta; Rau, Beate; De Reijke, Theo; Rubio, Isabel T.; Ruurda, Jelle; Soreide, Kjetil; Stättner, Stefan; Trapani, Dario; D'Ugo, Domenico; Vriens, Menno; Eriksson, Ane Gerda Zahl (Journal article; Peer reviewed, 2021)Introduction Surgical oncology is a defined specialty within the European Board of Surgery within the European Union of Medical Specialists (UEMS). Variation in training and specialization still occurs across Europe. There ... -
Fluid-sensitive migration mechanisms predict association between metastasis and high interstitial fluid pressure in pancreatic cancer
Nævdal, Geir; Rofstad, Einar K; Søreide, Kjetil; Evje, Steinar (Journal article; Peer reviewed, 2022)A remarkable feature in pancreatic cancer is the propensity to metastasize early, even for small, early stage cancers. We use a computer-based pancreatic model to simulate tumor progression behavior where fluid-sensitive ... -
Follow-up strategies for patients with splenic trauma managed non-operatively: the 2022 World Society of Emergency Surgery consensus document
Podda, Mauro; De Simone, Belinda; Ceresoli, Marco; Virdis, Francesco; Favi, Francesco; Larsen, Johannes Wiik; Coccolini, Federico; Sartelli, Massimo; Pararas, Nikolaos; Beka, Solomon Gurmu; Bonavina, Luigi; Bova, Raffaele; Pisanu, Adolfo; Abu-Zidan, Fikri; Balogh, Zsolt; Chiara, Osvaldo; Wani, Imtiaz; Stahel, Philip; Di Saverio, Salomone; Scalea, Thomas; Søreide, Kjetil; Sakakushev, Boris; Amico, Francesco; Martino, Costanza; Hecker, Andreas; de’Angelis, Nicola; Chirica, Mircea; Galante, Joseph; Kirkpatrick, Andrew; Pikoulis, Emmanouil; Kluger, Yoram; Bensard, Denis; Ansaloni, Luca; Fraga, Gustavo; Civil, Ian; Tebala, Giovanni Domenico; Di Carlo, Isidoro; Cui, Yunfeng; Coimbra, Raul; Agnoletti, Vanni; Sall, Ibrahima; Tan, Edward; Picetti, Edoardo; Litvin, Andrey; Damaskos, Dimitrios; Inaba, Kenji; Leung, Jeffrey; Maier, Ronald; Biffl, Walt; Leppaniemi, Ari; Moore, Ernest; Gurusamy, Kurinchi; Catena, Fausto (Journal article; Peer reviewed, 2022)Background In 2017, the World Society of Emergency Surgery published its guidelines for the management of adult and pediatric patients with splenic trauma. Several issues regarding the follow-up of patients with splenic ... -
Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains
Berg, Kaja Christine Graue; Sveen, Anita; Høland, Maren; Alagaratnam, Sharmini; Rasmussen, Marianne Berg; Danielsen, Stine Aske; Nesbakken, Arild; Søreide, Kjetil; Lothe, Ragnhild A (Peer reviewed; Journal article, 2019-07-15)About 80% of colorectal cancers (CRCs) have chromosomal instability, which is an integral part of aggressive malignancy development, but the importance of specific copy number aberrations (CNAs) in modulating gene expression, ... -
Genetic and Epigenetic Traits as Biomarkers in Colorectal Cancer
Berg, Marianne; Søreide, Kjetil (Peer reviewed; Journal article, 2011-12-16)Colorectal cancer is a major health burden, and a leading cause of cancer-related deaths in industrialized countries. The steady improvements in surgery and chemotherapy have improved survival, but the ability to identify ...