Browsing Department of Clinical Medicine by Author "Wang, Zhiyong"

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    • EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1 

      Ando, Toshinori; Arang, Nadia; Wang, Zhiyong; Costea, Daniela Elena; Feng, Xiaodong; Goto, Yusuke; Izumi, Hiroki; Gilardi, Mara; Ando, Kazuyo; Gutkind, J. Silvio (Journal article; Peer reviewed, 2021)
      The Hippo pathway is frequently dysregulated in cancer, leading to the unrestrained activity of its downstream targets, YAP/TAZ, and aberrant tumor growth. However, the precise mechanisms leading to YAP/TAZ activation in ...