Browsing Department of Clinical Medicine by Title
Now showing items 729-748 of 2065
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Experimental studies on the immune response to Ehrlich's ascites carcinoma
(Doctoral thesis, 1964-05-13) -
An exploratory assessment of the management of pediatric traumatic brain injury in three centers in Africa
(Journal article; Peer reviewed, 2022-08-17)Purpose: Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in low- and middle-income countries (LMICs). Hospital care practices of pediatric TBI patients in LMICs are unknown. Our objective was to ... -
Exploring the effects of lifestyle on breast cancer risk, age at diagnosis, and survival: the EBBA-Life study
(Journal article; Peer reviewed, 2020)Purpose Whether an unfavorable lifestyle not only affects breast cancer risk, but also influences age at onset of breast cancer and survival, is under debate. Methods In a population-based cohort, the Energy Balance ... -
Exploring the genetic contribution to idiopathic Parkinson disease
(Doctoral thesis, 2021-03-05)Background: Parkinson disease (PD) is a major cause of death and disability and has a devastating global socioeconomic impact. It affects 1-2% of the population above the age of 65 and its prevalence increases as the ... -
Exploring uncertainty and use of real-world data in the National Institute for Health and Care Excellence single technology appraisals of targeted cancer therapy
(Journal article; Peer reviewed, 2022)Objectives Dealing with uncertainty is one of the critical topics in health technology assessment. The greater decision uncertainty in appraisals, the less clear the clinical- and cost-effectiveness of the health technology. ... -
Exploring variables affecting sense of coherence and social support in recovery after colorectal cancer surgery among the oldest old
(Journal article; Peer reviewed, 2022)Objective To explore the associations between sense of coherence, perceived social support, and demographic and clinical characteristics among survivors ≥80 years treated for curable colorectal cancer. Methods This ... -
Exposure to environmental phenols and parabens, and relation to body mass index, eczema and respiratory outcomes in the Norwegian RHINESSA study
(Journal article; Peer reviewed, 2021)Background Many phenols and parabens are applied in cosmetics, pharmaceuticals and food, to prevent growth of bacteria and fungi. Whether these chemicals affect inflammatory diseases like allergies and overweight is largely ... -
Exposure to mycophenolate and fatherhood
(Peer reviewed; Journal article, 2017-07)Background: Mycophenolic acid (MPA) is the active immunosuppressive substance in both mycophenolate mofetil and mycophenolate sodium, and it is widely used after organ transplantation. In women, taking MPA is teratogenic ... -
Expression of ESE-3 Isoforms in Immunogenic and Tolerogenic Human Monocyte-Derived Dendritic Cells
(Peer reviewed; Journal article, 2012-11-19)Dendritic cells (DC) are the only hematopoietic cells expressing the epithelial specific Ets transcription factor ESE-3. Here we analyzed presence and quantity of isoforms ESE-3a, ESE-3b and ESE-3j in various immunogenic ... -
Expression of Heat Shock Protein 27 in Melanoma Metastases Is Associated with Overall Response to Bevacizumab Monotherapy: Analyses of Predictive Markers in a Clinical Phase II Study
(Journal article, 2016-05-11)The aim of this study was to identify potential predictive biomarkers in 35 patients with metastatic melanoma treated with anti-angiogenic bevacizumab monotherapy in a clinical phase II study. The immunohistochemical ... -
Expression of NGAL-specific cells and mRNA levels correlate with inflammation in the salivary gland, and its overexpression in the saliva, of patients with primary Sjögren’s syndrome
(Journal article; Peer reviewed, 2020)Salivary gland involvement is a characteristic feature of primary Sjögren’s syndrome (pSS), where tissue destruction is mediated by infiltrating immune cells, and may be accompanied by the presence of adipose tissue. ... -
Expression of the "stem cell marker" CD133 in pancreas and pancreatic ductal adenocarcinomas
(Peer reviewed; Journal article, 2008-02-08)Background It has been suggested that a small population of cells with unique self-renewal properties and malignant potential exists in solid tumors. Such "cancer stem cells" have been isolated by flow cytometry, followed ... -
Expression of thyroid transcription factor-1 is associated with a basal-like phenotype in breast carcinomas
(Peer reviewed; Journal article, 2013-05-15)Background: The differential diagnosis between primary and secondary breast cancers might be difficult, especially in poorly differentiated tumors. Thyroid Transcription Factor-1 (TTF-1) has been regarded as a reliable ... -
Expression of β-Catenin, E-Cadherin, and α-Smooth Muscle Actin in Basal Cell Carcinoma Before Photodynamic Therapy in Non-recurrent and Recurrent Tumors: Exploring the Ability of Predicting Photodynamic Therapy outcome
(Journal article; Peer reviewed, 2023)Photodynamic therapy (PDT) is an effective and cosmetically beneficial treatment of low-risk basal cell carcinomas (BCCs). To optimize PDT response, it is important to correctly select tumors. We sought to find markers ... -
Expression Profiling of Major Histocompatibility and Natural Killer Complex Genes Reveals Candidates for Controlling Risk of Graft versus Host Disease
(Peer reviewed; Journal article, 2011-01-28)Background: The major histocompatibility complex (MHC) is the most important genomic region that contributes to the risk of graft versus host disease (GVHD) after haematopoietic stem cell transplantation. Matching of MHC ... -
Extended-spectrum β-lactamase producing Klebsiella pneumoniae. A neonatal intensive care unit outbreak, long-term colonization in children and plasmid characteristics
(Doctoral thesis, 2014-12-19)Background: The increasing level of antimicrobial resistance among clinical relevant bacteria, especially the increasing prevalence of extended-spectrum β-lactamase (ESBL) producing Enterobacteriaceae, is of great concern ... -
Extensor tendon release in tennis elbow: results and prognostic factors in 80 elbows
(Peer reviewed; Journal article, 2011-03-16)Purpose The objectives of this study were to evaluate the results in the outpatient treatment of recalcitrant lateral epicondylitis with release of the common extensor origin according to Hohmann and to determine any ... -
External Hydrocephalus as a Cause of Infant Subdural Hematoma: Epidemiological and Radiological Investigations of Infants Suspected of Being Abused
(Journal article; Peer reviewed, 2022)Background Acute subdural hematoma (ASDH) and chronic subdural hematoma (CSDH) in infants have been regarded as highly specific for abuse. Other causes of CSDH have not been investigated in a large population. Purpose The ... -
External validation of SAPS II score reported to the Norwegian Intensive Care and Pandemic Registry (NIPaR)
(Journal article; Peer reviewed, 2023)Background: Simplified Acute Physiology Score II (SAPS II) is a mortality prediction model widely used to compensate for differences between intensive care units (ICU) in benchmarking and research. Accuracy of SAPS II is ...