Blar i Department of Clinical Medicine på tittel
Viser treff 1797-1816 av 2061
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Similar early mortality risk after cemented compared with cementless total hip arthroplasty for primary osteoarthritis: data from 188,606 surgeries in the Nordic Arthroplasty Register Association database
(Journal article; Peer reviewed, 2021)Background and purpose — Current literature indicates no difference in 90-day mortality after cemented compared with cementless total hip arthroplasty (THA). However, previous studies are hampered by potential selection ... -
Similar migration in computer-assisted and conventional total knee arthroplasty
(Peer reviewed; Journal article, 2017)Background and purpose — Computer-assisted surgery (CAS) in total knee arthroplasty (TKA) has been used in recent years in the hope of improving the alignment and positioning of the implant, thereby achieving a better ... -
Similarly low-blood metal ion levels at 10-years follow-up of total hip arthroplasties with Oxinium, CoCrMo, and stainless steel femoral heads. Data from a randomized clinical trial
(Journal article; Peer reviewed, 2022)The use of inert head materials such as ceramic heads has been proposed as a method of reducing wear and corrosion products from the articulating surfaces in total hip arthroplasty, as well as from the stem-head taper ... -
Simple limbal epithelial transplantation: Current status and future perspectives
(Peer reviewed; Journal article, 2019-12-04)Damage to limbal stem cells as a result of injury or disease can lead to limbal stem cell deficiency (LSCD). This disease is characterized by decreased vision that is often painful and may progress to blindness. Clinical ... -
A simple versatile solution for collecting multidimensional clinical data based on the CakePHP web application framework
(Peer reviewed; Journal article, 2014-04)Clinical trials aiming for regulatory approval of a therapeutic agent must be conducted according to Good Clinical Practice (GCP). Clinical Data Management Systems (CDMS) are specialized software solutions geared toward ... -
Simplifying the clinical classification of polymerase gamma (POLG) disease based on age of onset; studies using a cohort of 155 cases
(Journal article; Peer reviewed, 2020)Background Variants in POLG are one of the most common causes of inherited mitochondrial disease. Phenotypic classification of POLG disease has evolved haphazardly making it complicated and difficult to implement in ... -
Simulation-based team-training in acute stroke: Is it safe to speed up?
(Journal article; Peer reviewed, 2022)Background In acute ischemic stroke (AIS), rapid treatment with intravenous thrombolysis (IVT) is crucial for good clinical outcome. Weekly simulation-based team-training of the stroke treatment team was implemented, ... -
Simultaneous bilateral aqueous misdirection following certolizumab therapy for rheumatoid arthritis
(Journal article; Peer reviewed, 2020)Aqueous misdirection syndrome is a rare, incompletely understood, sight-threatening eye condition that is difficult to diagnose and treat. We present a case of simultaneous bilateral aqueous misdirection following the ... -
Simultaneous Resection of Primary Colorectal Cancer and Synchronous Liver Metastases: Contemporary Practice, Evidence and Knowledge Gaps
(Journal article; Peer reviewed, 2021)The timing of surgical resection of synchronous liver metastases from colorectal cancer has been debated for decades. Several strategies have been proposed, but high-level evidence remains scarce. Simultaneous resection ... -
Single use flexible ureteroscopes: Current status and future directions
(Journal article; Peer reviewed, 2023)Introduction: Single use ureteroscopes are a technological innovation that have become available in the past decade and gained increased popularity. To this end, there are now an increasing number of both benchside and ... -
Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
(Journal article; Peer reviewed, 2021)Prostate cancer is heterogeneous and patients would benefit from methods that stratify those who are likely to respond to systemic therapy. Here, we employ single-cell assays for transposase-accessible chromatin (ATAC) and ... -
Six versus 2 weeks treatment with doxycycline in European Lyme neuroborreliosis: a multicentre, noninferiority, double-blinded, randomised and placebocontrolled trial
(Journal article; Peer reviewed, 2022)Background There is limited evidence regarding optimal duration of antibiotic treatment in neuroborreliosis. We aimed to compare efficacy and safety of oral doxycycline for 2 and 6 weeks in European Lyme neuroborreliosis ... -
Six versus two weeks treatment with doxycycline in Lyme neuroborreliosis: the protocol of a multicentre, non-inferiority, double-blinded and randomised controlled trial
(Peer reviewed; Journal article, 2019)Introduction: Current treatment guidelines for European Lyme neuroborreliosis (LNB) recommend cephalosporins, penicillin or doxycycline for 14–28 days but evidence for optimal treatment length is poor. Treatment lengths ... -
Sixteen-week multicentre randomised controlled trial to study the effect of the consumption of an oat beta-glucanenriched bread versus a whole-grain wheat bread on glycaemic control among persons with pre-diabetes: a study protocol of the CarbHealth study
(Journal article; Peer reviewed, 2022)Introduction In 2012, the estimated global prevalence of pre-diabetes was 280 million, and the prevalence is expected to rise to 400 million by 2030. Oat-based foods are a good source of beta-glucans, which have been ... -
Sjögren’s syndrome: studying the disease in mice
(Peer reviewed; Journal article, 2011-06-13)Sjögren’s syndrome (SS), a systemic autoimmune disease, is characterized by infl ammation of exocrine tissues accompanied by a signifi cant loss of their secretory function. Clinical symptoms develop late and there are no ... -
Sjøfolks syn- har vi riktig fokus på helsekrav og undersøkelsesmetode?
(Journal article, 2008)En vanlig synsundersøkelse måler skarpsyn, men sier ingenting om evnen til å se kontraster. Spesielt i mørke, tåke eller motlys er godt kontrastsyn vel så viktig, når man holder utkikk på broen. -
Sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study
(Peer reviewed; Journal article, 2013-02-14)Background: Our aim was to compare subjective and objective sleep quality and arousal in migraine and to evaluate the relationship between sleep quality and pain thresholds (PT) in controls, interictal, preictal and postictal ... -
Sleep-related and non-sleep-related migraine: interictal sleep quality, arousals and pain thresholds
(Peer reviewed; Journal article, 2013-08-06)Background: The mechanisms associating sleep and migraine are unknown. No previous polysomnographic (PSG) or pain-threshold (PT) study has compared patients with sleep-related migraine attacks (SM), non-sleep related ... -
Social media in surgery: evolving role in research communication and beyond
(Journal article; Peer reviewed, 2021)Purpose To present social media (SoMe) platforms for surgeons, how these are used, with what impact, and their roles for research communication. Methods A narrative review based on a literature search regarding social ... -
SonoVue® vs. Sonazoid™ vs. Optison™: Which Bubble Is Best for Low-Intensity Sonoporation of Pancreatic Ductal Adenocarcinoma?
(Journal article; Peer reviewed, 2022)The use of ultrasound and microbubbles to enhance therapeutic efficacy (sonoporation) has shown great promise in cancer therapy from in vitro to ongoing clinical studies. The fastest bench-to-bedside translation involves ...