Browsing Department of Clinical Medicine by Author "Assmus, Jörg"
Now showing items 1-20 of 20
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Amoxicillin did not Reduce Modic Change Oedema in Patients with Chronic Low Back pain - subgroup Analyses of a Randomised Trial (the AIM study)
Kristoffersen, Per Martin; Vetti, Nils; Grøvle, Lars; Brox, Jens Ivar; Bråten, Lars Christian Haugli; Grotle, Margreth; Haugen, Anne Julsrud; Rolfsen, Mads Peder; Froholdt, Anne; Skouen, Jan Sture; Lutro, Olav; Marchand, Gunn Hege; Anke, Audny Gabriele Wagner; Zwart, John Anker Henrik; Storheim, Kjersti; Assmus, Jörg; Espeland, Ansgar (Journal article; Peer reviewed, 2022)Study Design. Exploratory subgroup analyses of a randomised trial [Antibiotics in Modic changes (AIM) study]. Objective. The aim was to assess the effect of amoxicillin versus placebo in reducing Modic change (MC) ... -
Antibiotic treatment In patients with chronic low back pain and Modic changes (the AIM study): study protocol for a randomised controlled trial
Storheim, Kjersti; Espeland, Ansgar; Grøvle, Lars; Skouen, Jan Sture; Assmus, Jörg; Anke, Audny; Froholdt, Anne; Pedersen, LM; Haugen, AJ; Fors, Terese; Schistad, Ellina Iordanova; Lutro, Olav; Marchand, Gunn Hege; Kadar, Thomas; Vetti, Nils; Randen, Solfrid; Nygaard, Øystein Petter; Brox, Jens Ivar; Grotle, Margreth; Zwart, JA (Peer reviewed; Journal article, 2017-12-15)Background: A previous randomised controlled trial (RCT) of patients with chronic low back pain (LBP) and vertebral bone marrow (Modic) changes (MCs) on magnetic resonance imaging (MRI), reported that a 3-month, high-dose ... -
Apparent diffusion coefficient values in Modic changes – interobserver reproducibility and relation to Modic type
Dagestad, Magnhild Hammersland; Vetti, Nils; Kristoffersen, Per M; Zwart, John Anker Henrik; Storheim, Kjersti; Bakland, Gunnstein; Brox, Jens Ivar; Grøvle, Lars; Marchand, Gunn Hege; Andersen, Erling; Assmus, Jörg; Espeland, Ansgar (Journal article; Peer reviewed, 2022)Background Modic Changes (MCs) in the vertebral bone marrow were related to back pain in some studies but have uncertain clinical relevance. Diffusion weighted MRI with apparent diffusion coefficient (ADC)-measurements ... -
Blue-blocking glasses as additive treatment for mania: A randomized placebo-controlled trial
Henriksen, Tone Elise Gjøtterud; Skrede, Silje; Fasmer, Ole Bernt; Schøyen, Helle Kristine; Leskauskaite, Ieva; Bjørke-Bertheussen, Janette; Assmus, Jörg; Hamre, Børge; Grønli, Janne; Lund, Anders (Peer reviewed; Journal article, 2016-05)Objectives: The discovery of the blue lightsensitive retinal photoreceptor responsible for signaling daytime to the brain suggested that light to the circadian system could be inhibited by using blue-blocking orange tinted ... -
Comparison of Performance Score for Female and Male Residents in General Surgery Doing Supervised Real-Life Laparoscopic Appendectomy: Is There a Norse Shield-Maiden Effect?
Skjold-Ødegaard, Benedicte; Ersdal, Hege Langli; Assmus, Jörg; Søreide, Kjetil (Journal article; Peer reviewed, 2021)Background Gender bias may represent a threat to resident assessment during surgical training, and there have been concerns that women might be disadvantaged. There is a lack of studies investigating gender differences ... -
Cytokine Patterns in Tuberculosis Infection; IL-1ra, IL-2 and IP-10 Differentiate Borderline QuantiFERON-TB Samples from Uninfected Controls
Wergeland, Ida; Assmus, Jörg; Dyrhol-Riise, Anne Ma (Peer reviewed; Journal article, 2016-09-29)Background: Interferon gamma release assays (IGRAs) do not discriminate between active tuberculosis (TB) and latent TB infection (LTBI), which limit their use in TB endemic areas. Subjects with QuantiFERON-TB (QFT) results ... -
Development and clinical implementation of a structured, simulation-based training programme in laparoscopic appendectomy: Description, validation and evaluation
Skjold-Ødegaard, Benedicte; Ersdal, Hege Langli; Assmus, Jörg; Nedrebø, Bjørn Steinar Olden; Sjo, Ole; Søreide, Kjetil (Journal article; Peer reviewed, 2021)Background: Laparoscopic appendectomy is a common procedure in general surgery but is likely underused in structured and real-life teaching. This study describes the development, validation and evaluation of implementing ... -
Dixon T2 imaging of vertebral bone edema: reliability and comparison with short tau inversion recovery
Dagestad, Magnhild Hammersland; Toppe, Monika Kolskår; Kristoffersen, Per M; Gjefsen, Elisabeth; Andersen, Erling; Assmus, Jörg; Vetti, Nils; Espeland, Ansgar (Journal article; Peer reviewed, 2022)Background It is uncertain whether T2-weighted Dixon water images (DixonT2w) and short tau inversion recovery (STIR) are interchangeable when evaluating vertebral bone edema, or if one method is superior or visualizes the ... -
Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial
Bråten, Lars Christian Haugli; Rolfsen, Mads Peder; Espeland, Ansgar; Wigemyr, Monica; Assmus, Jörg; Froholdt, Anne; Haugen, Anne Julsrud; Marchand, Gunn Hege; Kristoffersen, Per M; Lutro, Olav; Randen, Sigrun; Wilhelmsen, Maja; Winsvold, Bendik K S; Kadar, Thomas; Holmgard, Thor Einar; Vigeland, Maria Dehli; Vetti, Nils; Nygaard, Øystein Petter; Lie, Benedicte Alexandra; Hellum, Christian; Anke, Audny; Grotle, Margreth; Schistad, Ellina Iordanova; Skouen, Jan Sture; Grøvle, Lars; Brox, Jens Ivar; Zwart, John-Anker; Storheim, Kjersti (Peer reviewed; Journal article, 2019)Objective To assess the efficacy of three months of antibiotic treatment compared with placebo in patients with chronic low back pain, previous disc herniation, and vertebral endplate changes (Modic changes). Design Double ... -
Factors associated with self-rated health in a Norwegian population of older people participating in a preventive home visit program: a cross-sectional study
Fjell, Astrid; Cronfalk, Berit Seiger; Hermann, Monica; Rongve, Arvid; Assmus, Jörg; Kvinge, Lars Malvin Røsseland; Seiger, Åke; Skaug, Knut; Boström, Anne-Marie (Journal article; Peer reviewed, 2020)Background Assessing self-rated health by preventive home visits of older people can provide information about the person’s well-being, quality of life and risk of developing illness. The aim of this study was to examine ... -
Factors influencing on-scene time in a rural Norwegian helicopter emergency medical service: A retrospective observational study
Østerås, Øyvind; Heltne, Jon-Kenneth; Vikenes, Bjarne H; Assmus, Jörg; Brattebø, Guttorm (Peer reviewed; Journal article, 2017-09-21)Background: Critically ill patients need to be immediately identified, properly managed, and rapidly transported to definitive care. Extensive prehospital times may increase mortality in selected patient groups. The on-scene ... -
Gastric function in diabetic gastroparesis assessed by ultrasound and scintigraphy
Steinsvik, Elisabeth Kjelsvik; Sangnes, Dag A.; Søfteland, Eirik; Biermann, Martin; Assmus, Jörg; Dimcevski, Georg Gjorgji; Gilja, Odd Helge; Hausken, Trygve (Journal article; Peer reviewed, 2021)Background: Gastroparesis is a severe diabetes complication characterized by delayed gastric emptying. We examined patients with symptoms of diabetic gastroparesis using gastric emptying scintigraphy and ultrasound drink ... -
Investigating novel biomarkers of immune activation and modulation in the context of sedentary behaviour: a multicentre prospective ischemic stroke cohort study
Alme, Katinka Nordheim; Askim, Torunn; Assmus, Jörg; Mollnes, Tom Eirik; Naik, Mala; Næss, Halvor; Saltvedt, Ingvild; Ueland, Per-Magne; Ulvik, Arve; Knapskog, Anne-Brita (Journal article; Peer reviewed, 2021)Background Sedentary behaviour is associated with disease, but the molecular mechanisms are not understood. Valid biomarkers with predictive and explanatory properties are required. Therefore, we have investigated traditional ... -
Low birthweight is associated with lower glomerular filtration rate in middle-aged mainly healthy women
Lillås, Bjørn Steinar; Tøndel, Camilla; Assmus, Jörg; Vikse, Bjørn Egil (Journal article; Peer reviewed, 2020)Background Low birthweight (LBW) has been shown to increase the risk of severe kidney disease. Studies have also shown associations between LBW and lower estimated glomerular filtration rate (GFR) in young adults. In this ... -
Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of infammation measured three months after ischemic stroke
Alme, Katinka Nordheim; Ulvik, Arve; Askim, Torunn; Assmus, Jörg; Mollnes, Tom Eirik; Naik, Mala; Næss, Halvor; Saltvedt, Ingvild; Ueland, Per-Magne; Knapskog, Anne Brita (Journal article; Peer reviewed, 2021)Background Chronic low-grade inflammation is associated with both ischemic stroke and sedentary behaviour. The aim of this study was to investigate the predictive abilities of biomarkers of inflammation and immune modulation ... -
NOR-SASS (Norwegian Sonothrombolysis in Acute Stroke Study): Randomized controlled contrast-enhanced sonothrombolysis in an unselected acute ischemic stroke population
Nacu, Aliona; Kvistad, Christopher Elnan; Næss, Halvor; Øygarden, Halvor; Logallo, Nicola; Assmus, Jörg; Waje-Andreassen, Ulrike; Kurz, Kathinka Dæhli; Neckelmann, Gesche F; Thomassen, Lars (Peer reviewed; Journal article, 2016-02)Background and Purpose—The NOR-SASS (Norwegian Sonothrombolysis in Acute Stroke Study) aimed to assess effect and safety of contrast-enhanced ultrasound treatment in an unselected acute ischemic stroke population. ... -
Oedema on STIR modified the effect of amoxicillin as treatment for chronic low back pain with Modic changes—subgroup analysis of a randomized trial
Kristoffersen, Per M; Bråten, Lars Christian Haugli; Vetti, Nils; Grøvle, Lars; Hellum, Christian; Storheim, Kjersti; Zwart, John-Anker; Assmus, Jörg; Espeland, Ansgar (Journal article; Peer reviewed, 2021)Objective To evaluate potential MRI-defined effect modifiers of amoxicillin treatment in patients with chronic low back pain and type 1 or 2 Modic changes (MCs) at the level of a previous lumbar disc herniation (index ... -
The outcome of primary per oral endoscopic myotomy (POEM) for treatment of achalasia: Norwegian single-center experience with long-term follow-up
Pham, Khanh Do-Cong; Lauritzen, Sigurd; Tjora, Erling; Gilja, Odd Helge; Hatlebakk, Jan Gunnar; Assmus, Jörg; Havre, Roald Flesland (Journal article; Peer reviewed, 2022)Background and aims: Per oral endoscopic myotomy (POEM) has become an established treatment for achalasia, but no Scandinavian studies with long-term follow-up exist. This study from a tertiary referral center in Norway ... -
Short tau inversion recovery MRI of Modic changes: a reliability study
Kristoffersen, Per M; Vetti, Nils; Storheim, Kjersti; Bråten, Lars Christian Haugli; Rolfsen, Mads Peder; Assmus, Jörg; Espeland, Ansgar (Journal article; Peer reviewed, 2020)Background Limited reliability data exist for evaluation of spinal edema changes on magnetic resonance imaging (MRI) with short tau inversion recovery (STIR) sequences. Purpose To assess the inter-observer reliability ... -
Survival and cause of death in multiple sclerosis: A 60-year longitudinal population study
Lunde, Hanne Marie; Assmus, Jörg; Myhr, Kjell-Morten; Bø, Lars; Grytten, Nina (Peer reviewed; Journal article, 2017)Objective: Survival and causes of death (COD) in multiple sclerosis (MS) provide ultimate endpoints. We aimed to investigate survival and COD in a 60-year population-based MS cohort compared with the general population. ...