Blar i Department of Clinical Medicine på tittel
Viser treff 1216-1235 av 2095
-
Long-term recovery after colorectal cancer surgery among the old: a qualitative study
(Journal article; Peer reviewed, 2023)Background Colorectal cancer is the third most frequently diagnosed cancer worldwide, disproportionally affecting older people. With modern treatment, older people are surviving cancer treatment and recovery. However, ... -
The Long-Term Risk of Knee Arthroplasty in Patients with Arthroscopically Verified Focal Cartilage Lesions: A Linkage Study with the Norwegian Arthroplasty Register, 1999 to 2020
(Journal article; Peer reviewed, 2023)Background: Focal cartilage lesions are common in the knee. The risk of later ipsilateral knee arthroplasty remains unknown. The purposes of the present study were to evaluate the long-term cumulative risk of knee ... -
Long-term survival and quality of life after intensive care for patients 80 years of age or older
(Peer reviewed; Journal article, 2015-06-03)Background: Comparison of survival and quality of life in a mixed ICU population of patients 80 years of age or older with a matched segment of the general population. Methods: We retrospectively analyzed survival of ICU ... -
Long-term survival from adenocarcinoma of the esophagus after transthoracic and transhiatal esophagectomy
(Peer reviewed; Journal article, 2012-06-30)Background: The effects of transthoracic or transhiatal esophagectomy on the long-term survival of patients who had adenocarcinoma of the esophagus were compared, as were factors applicable in preoperative stratification ... -
Long-Term Survival in 1,931 Patients With Dizziness: Disease- and Symptom-Specific Mortality
(Journal article; Peer reviewed, 2021)Objective: To evaluate mortality among patients referred for suspected vestibular disorder and to examine whether specific symptoms or disorders predict long-term survival among patients with dizziness or vertigo. Study ... -
Long-term survival of 2997 finger metacarpophalanageal joint arthroplasties from the Norwegian Arthroplasty Register
(Journal article; Peer reviewed, 2022)We present the long-time survival of 2997 primary metacarpophalangeal (MCP) joint implants from the Norwegian Arthroplasty Register from 1994 to 2019. Six different implants were compared in terms of survival and risk of ... -
Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes
(Journal article; Peer reviewed, 2023-07-21)Long-term antibiotics are prescribed for a variety of medical conditions, recently including low back pain with Modic changes. The molecular impact of such treatment is unknown. We conducted longitudinal transcriptome and ... -
Longer-term quality of care, effectiveness, and cost-effectiveness of implementing a model of care for osteoarthritis: A cluster-randomized controlled trial
(Journal article; Peer reviewed, 2024)Objective: To assess the quality of care, effectiveness, and cost-effectiveness over 12 months after implementing a structured model of care for hip and knee osteoarthritis (OA) in primary healthcare as compared to usual ... -
Longevity of B-cell and T-cell responses after live attenuated influenza vaccination in children
(Peer reviewed; Journal article, 2015-05-15)Background. The live attenuated influenza vaccine (LAIV) is the preferred vaccine for children, but the mechanisms behind protective immune responses are unclear, and the duration of immunity remains to be elucidated. This ... -
Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease
(Journal article; Peer reviewed, 2023)Background Brain innate immune activation is associated with Alzheimer’s disease (AD), but degrees of activation may vary between disease stages. Thus, brain innate immune activation must be assessed in longitudinal ... -
Longitudinal effects of adjuvant chemotherapy and lymph node staging on patient-reported outcomes in endometrial cancer survivors: a prospective cohort study
(Journal article; Peer reviewed, 2021)Background: Most patients with endometrial cancer with localized disease are effectively treated and survive for a long time. The primary treatment is hysterectomy, to which surgical staging procedures may be added to ... -
Longitudinal follow-up of employment status in patients with chronic fatigue syndrome after mononucleosis
(Peer reviewed; Journal article, 2015-11-26)Objective: To examine the effect of early clinical and demographic factors on occupational outcome, return to work or awarded permanent disability pension in young patients with chronic fatigue syndrome (CFS). Design: ... -
Longitudinal Relationship Between Reduced Modic Change Edema and Disability and Pain in Patients With Chronic Low Back Pain
(Journal article; Peer reviewed, 2023)Study Design. Secondary analyses of a randomized trial [Antibiotics In Modic changes (MCs) study]. Objective. To assess whether or not reduced MC edema over time is related to reduced disability and pain in patients ... -
A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue
(Peer reviewed; Journal article, 2019-01-06)High mammographic density (MD) is associated with a 4–6 times increase in breast cancer risk. For post-menopausal women,MD often decreases over time, but little is known about the underlying biological mechanisms. MD ... -
Loss of epigenetic suppression of retrotransposons with oncogenic potential in aging mammary luminal epithelial cells
(Journal article; Peer reviewed, 2023)A primary function of DNA methylation in mammalian genomes is to repress transposable elements (TEs). The widespread methylation loss that is commonly observed in cancer cells results in the loss of epigenetic repression ... -
Loss of S100A14 expression at the tumor-invading front correlates with poor differentiation and worse prognosis in oral squamous cell carcinoma
(Journal article; Peer reviewed, 2020)Background We previously showed a tumor‐suppressive function of S100A14 in oral squamous cell carcinoma (OSCC). This study aimed to examine the prognostic significance and differentiation‐related function of S100A14 in ... -
The Low Affinity Nerve Growth Factor Receptor p75NTR Identifies a Transient Stem Cell-Like State in Oral Squamous Cell Carcinoma Cells
(Peer reviewed; Journal article, 2014-09-12)Background Although several markers have been used for enrichment of cells with stem cell-like properties in oral squamous cell carcinoma (OSCC), isolation of a pure subpopulation is still a challenging task. Normal oral ... -
Low birth weight and risk of progression to end stage renal disease in IgA nephropathy - A retrospective registry-based cohort study
(Peer reviewed; Journal article, 2016-04-19)Background: Low Birth Weight (LBW) is a surrogate for fetal undernutrition and is associated with impaired nephron development in utero. In this study, we investigate whether having been born LBW and/or small for gestational ... -
Low birth weight and risk of progressive kidney disease. Epidemiological and morphological studies
(Doctoral thesis, 2016-10-19)Background: Low Birth Weight (LBW) and Small for Gestation Age (SGA) are surrogate markers for fetal undernutrition and are associated with impaired nephron development in utero as suggested by the Brenner`s hypothesis. ... -
Low birth weight, intrauterine growth restriction and risk of chronic kidney disease in adult age
(Doctoral thesis, 2022-06-16)Background and aims: Studies have shown that adults with low birth weight (LBW) face an increased risk for chronic kidney disease (CKD), high blood pressure and cardiovascular disease (CVD). Previous Norwegian studies have ...