Blar i Department of Clinical Medicine på tittel

Viser treff 1240-1259 av 2186

    • The link between periodontal disease and rheumatoid arthritis: An updated review 

      Koziel, Joanna; Mydel, Piotr Mateusz; Potempa, Jan (Peer reviewed; Journal article, 2014-01)
      Porphyromonas gingivalis is a leading pathogen in chronic periodontitis, a disease process involving progressive destruction of the tissues that support the teeth. Recently, the organism has been reported to produce a ...

    • Lipid-Lowering Effects of Tetradecylthioacetic Acid in Antipsychotic-Exposed, Female Rats: Challenges with Long-Term Treatment 

      Skrede, Silje; Fernø, Johan; Bjørndal, Bodil; Brede, Wenche Rødseth; Bohov, Pavol; Berge, Rolf Kristian; Steen, Vidar Martin (Peer reviewed; Journal article, 2012-11-30)
      Background: Psychiatric patients often require chronic treatment with antipsychotic drugs, and while rats are frequently used to study antipsychotic-induced metabolic adverse effects, long-term exposure has only partially ...

    • Lipocalin 2 expression is associated with aggressive features of endometrial cancer 

      Mannelqvist, Monica; Stefansson, Ingunn; Wik, Elisabeth; Kusonmano, Kanthida; Ræder, Maria B.; Øyan, Anne Margrete; Kalland, Karl-Henning; Moses, Marsha A.; Salvesen, Helga Birgitte; Akslen, Lars A. (Peer reviewed; Journal article, 2012-05-06)
      Background: Increased expression of lipocalin 2 (LCN2) has been observed in several cancers. The aim of the present study was to investigate LCN2 in endometrial cancer in relation to clinico-pathologic phenotype, angiogenesis, ...

    • Lipogenic effects of antipsychotic drugs in cultured cells and in rat 

      Fernø, Johan (Doctoral thesis, 2007-05-10)
      The etiology of the serious psychiatric disorder schizophrenia is unknown. Epidemiological studies indicate a high heritability with a complex pattern of transmission. Moreover, structural and genetic findings indicate ...

    • Listening to the polar oceans : Monitoring and mapping marine ecosystems using passive and active acoustics 

      Menze, Sebastian (Doctoral thesis, 2020-06-12)
      This interdisciplinary thesis uses active and passive acoustics to study the polar marine ecosystems. The polar oceans are some of the most remote, harshest and least well studied environments of the planet, and also the ...

    • Live well, die well - an international cohort study on experiences, concerns and preferences of patients in the last phase of life: the research protocol of the iLIVE study 

      Yildiz, Berivan; Allan, Simon; Bakan, Misa; Barnestein-Fonseca, Pilar; Berger, Michael; Boughey, Mark; Christen, Andri; De Simone, Gustavo G; Egloff, Martina; Ellershaw, John; Elsten, Eline E. C. M.; Eychmüller, Steffen; Fischer, Claudia; Fürst, Carl Johan; Geijteman, Eric C. T.; Goldraij, Gabriel; Goossensen, Anne; Halfdanardottir, Svandis Iris; Haugen, Dagny Renata Faksvåg; Hedman, Christel; Hoppe, Tanja; Hughes, Rosemary; Iversen, Grethe Skorpen; Joshi, Melanie; Kodba-Ceh, Hana; Korfage, Ida J; Lunder, Urska; Lüthi, Nora; Martín-Roselló, Maria Luisa; Mason, Stephen; Mcglinchey, Tamsin; Montilla, Silvi; Rasmussen, Birgit H; Ruiz-Torreras, Inmaculada; Schelin, Maria E. C.; Sigurdardottir, Katrin Rut; Sigurdardottir, Valgerdur; Simon, Judith; Smeding, Ruthmarijke; Solvåg, Kjersti; Strupp, Julia; Tripodoro, Vilma; Van Der Kuy, Hugo M; Van Der Rijt, Carin C. D.; Van Zuylen, Lia; Veloso, Verónica I; Vibora-Martin, Eva; Voltz, Raymond; Zambrano, Sofia C; Van Der Heide, Agnes (Journal article; Peer reviewed, 2022)
      Introduction Adequately addressing the needs of patients at the end of life and their relatives is pivotal in preventing unnecessary suffering and optimising their quality of life. The purpose of the iLIVE study is to ...

    • Liver elastography in healthy children using three different systems - how many measurements are necessary? 

      Mjelle, Anders Batman; Mulabecirovic, Anesa; Havre, Roald Flesland; Olafsdottir, Edda Jonina; Gilja, Odd Helge; Vesterhus, Mette (Journal article; Peer reviewed, 2020-12-21)
      Purpose Liver elastography is increasingly being applied in screening for and follow-up of pediatric liver disease, and has been shown to correlate well with fibrosis staging through liver biopsy. Because time is of the ...

    • Liver Elastography in Primary Sclerosing Cholangitis Patients Using Three Different Scanner Systems 

      Mjelle, Anders Batman; Fossdal, Guri; Gilja, Odd Helge; Vesterhus, Mette (Journal article; Peer reviewed, 2020)
      The aim of the study described here was to characterize three different liver elastography methods in primary sclerosing cholangitis (PSC) patients, for the first time exploring 2-D shear wave elastography (2-D-SWE) in PSC ...

    • Liver X receptors induce antiproliferative effects in basal-like breast cancer 

      Haugen, Mads; von der Lippe Gythfeldt, Hedda; Egeland, Eivind Valen; Svartdal Normann, Lisa; Pandya, Abhilash D.; Vedin, Lise-Lotte; Juell, Siri; Tenstad, Ellen; Øy, Geir Frode; Kristian, Alexandr; Marangoni, Elisabetta; Sørlie, Therese; Steffensen, Knut Rune; Mælandsmo, Gunhild Mari; Engebråten, Olav (Journal article; Peer reviewed, 2023)
      Liver X receptors (LXRs) are nuclear transcription factors important in the regulation of cholesterol transport, and glucose and fatty acid metabolism. The antiproliferative role of LXRs has been studied in a variety of ...

    • The liver-first approach for synchronous colorectal liver metastases: A systematic review and meta-analysis of completion rates and effects on survival 

      Zeyara, Adam; Torén, William; Søreide, Kjetil; Andersson, Roland (Journal article; Peer reviewed, 2021)
      Background: Patients presenting with synchronous colorectal liver metastases are increasingly being considered for a curative treatment, and the liver-first approach is gaining popularity in this context. However, little ...

    • Local Treatment of Recurrent Renal Cell Carcinoma May Have a Significant Survival Effect Across All Risk-of-recurrence Groups 

      Marconi, Lorenzo; Kuusk, Teele; Capitanio, Umberto; Beisland, Christian; Lam, Thomas; Pello, Sergio Fernandez; Stewart, Grant D.; Klatte, Tobias; Volpe, Alessandro; Ljungberg, Borje; Dabestani, Saeed; Bex, Axel (Journal article; Peer reviewed, 2023)
      Background Retrospective comparative studies suggest a survival benefit after complete local treatment of recurrence (LTR) in renal cell carcinoma (RCC), which may be largely due to an indication bias. Objective To ...

    • Localization of CDR2L and CDR2 in paraneoplastic cerebellar degeneration 

      Herdlevær, Ida Ajvazi; Kråkenes, Torbjørn; Schubert, Manja; Vedeler, Christian A. (Journal article; Peer reviewed, 2020)
      Objective: Identify the subcellular location and potential binding partners of two cerebellar degeneration‐related proteins, CDR2L and CDR2, associated with anti‐Yo‐mediated paraneoplastic cerebellar degeneration. Methods: ...

    • LOCATOR: feature extraction and spatial analysis of the cancer tissue microenvironment using mass cytometry imaging technologies 

      Ehsani, Rezvan; Jonassen, Inge; Akslen, Lars Andreas; Kleftogiannis, Dimitrios (Journal article; Peer reviewed, 2023)
      Motivation Recent advances in highly multiplexed imaging have provided unprecedented insights into the complex cellular organization of tissues, with many applications in translational medicine. However, downstream ...

    • Long term clinical disease progression in patients with Parkinson’s disease after STN Deep Brain Stimulation 

      Lilleeng, Bård Flattun (Doctoral thesis, 2016-02-12)
      Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder with severe longterm impact on patients, their caregivers and on the society in general [1]. The treatment of PD is symptomatic. Surgical ...

    • Long term outcomes and causal modelling of compulsory inpatient and outpatient mental health care using Norwegian registry data : protocol for a controversies in psychiatry research project 

      Hofstad, Tore; Nyttingnes, Olav; Markussen, Simen; Johnsen, Erik; Killackey, Eoin; McDaid, David; Rinaldi, Miles; Dean, Kimberlie; Brinchmann, Beate; Douglas, Kevin Stewart; Gröning, Linda; Bjørkly, Stål Kapstø; Palmstierna, Tom Krisman Kule; Strømme, Maria Fagerbakke; Blindheim, Anne Alnes; Rugkåsa, Jorun; Hofmann, Bjørn Morten; Pedersen, Reidar; Widding-Havnerås, Tarjei; Rypdal, Knut; Mykletun, Arnstein (Journal article; Peer reviewed, 2023)
      Objectives: Compulsory mental health care includes compulsory hospitalisation and outpatient commitment with medication treatment without consent. Uncertain evidence of the effects of compulsory care contributes to large ...

    • Long-range evolutionary constraints reveal cis-regulatory interactions on the human X chromosome 

      Naville, Magali; Ishibashi, Minaka; Ferg, Marco; Bengani, Hemant; Rinkwitz, Silke; Krecsmarik, Monika; Hawkins, Thomas A.; Wilson, Stephen W.; Manning, Elizabeth; Chilamakuri, Chandra Sekhar Reddy; Wilson, David I.; Louis, Alexandra; Raymond, F. Lucy; Rastegar, Sepand; Strähle, Uwe; Lenhard, Boris; Bally-Cuif, Laure; van Heyningen, Veronica; Fitzpatrick, David R.; Becker, Thomas S.; Crollius, Hugues Roest (Peer reviewed; Journal article, 2015-04-24)
      Enhancers can regulate the transcription of genes over long genomic distances. This is thought to lead to selection against genomic rearrangements within such regions that may disrupt this functional linkage. Here we test ...

    • Long-term effectiveness of cognitive behavior therapy for youth with anxiety disorders: Outcome, predictors and social anxiety 

      Kodal, Arne (Doctoral thesis, 2018-06-01)
      Cognitive behavioral therapy (CBT) has demonstrated favorable long-term outcomes in youth with anxiety disorders in efficacy trials. However, long-term outcomes of CBT delivered in a community setting are uncertain. The ...

    • Long-term effectiveness of cognitive behavioral therapy for youth with anxiety disorders 

      Kodal, Arne; Fjermestad, Krister; Bjelland, Ingvar; Gjestad, Rolf; Øst, Lars Gøran; Bjåstad, Jon Fauskanger; Haugland, Bente Storm Mowatt; Havik, Odd E.; Heiervang, Einar; Wergeland, Gro Janne (Peer reviewed; Journal article, 2018-01)
      Cognitive behavioral therapy (CBT) has demonstrated favorable long-term outcomes in youth with anxiety disorders in efficacy trials. However, long-term outcomes of CBT delivered in a community setting are uncertain. This ...

    • Long-term effects of conservative management of vestibular schwannoma on dizziness, balance, and caloric function 

      Nilsen, Kathrin Skorpa; Lund-Johansen, Morten; Nordahl, Stein Helge; Finnkirk, Monica Katrine; Goplen, Frederik Kragerud (Peer reviewed; Journal article, 2019)
      Objectives: To study the development of dizziness, caloric function, and postural sway during long-term observation of untreated vestibular schwannoma patients. Study Design: Retrospective review of a prospectively ...

    • Long-term effects of fecal microbiota transplantation (FMT) in patients with irritable bowel syndrome 

      El-Salhy, Magdy; Bråthen Kristoffersen, Anja; Valeur, Jørgen; Casén, Christina; Hatlebakk, Jan Gunnar; Gilja, Odd Helge; Hausken, Trygve (Journal article; Peer reviewed, 2021)
      Background We recently found fecal microbiota transplantation (FMT) in irritable bowel syndrome (IBS) patients to be an effective and safe treatment after 3 months. The present follow-up study investigated the efficacy ...