• Similar migration in computer-assisted and conventional total knee arthroplasty 

      Petursson, Gunnar; Fenstad, Anne Marie; Gøthesen, Øystein; Haugan, Kristin; Dyrhovden, Gro Sævik; Halland, Geir; Röhrl, Stephan Maximillian; Aamodt, Arild; Nilsson, Kjell G.; Furnes, Ove (Peer reviewed; Journal article, 2017)
      Background and purpose — Computer-assisted surgery (CAS) in total knee arthroplasty (TKA) has been used in recent years in the hope of improving the alignment and positioning of the implant, thereby achieving a better ...
    • Simple limbal epithelial transplantation: Current status and future perspectives 

      Jackson, Catherine; Ernø, Ina Myklebust; Ringstad, Håkon; Tønseth, Kim Alexander; Dartt, Darlene Ann; Utheim, Tor Paaske (Peer reviewed; Journal article, 2019-12-04)
      Damage to limbal stem cells as a result of injury or disease can lead to limbal stem cell deficiency (LSCD). This disease is characterized by decreased vision that is often painful and may progress to blindness. Clinical ...
    • A simple versatile solution for collecting multidimensional clinical data based on the CakePHP web application framework 

      Biermann, Martin (Peer reviewed; Journal article, 2014-04)
      Clinical trials aiming for regulatory approval of a therapeutic agent must be conducted according to Good Clinical Practice (GCP). Clinical Data Management Systems (CDMS) are specialized software solutions geared toward ...
    • Simplifying the clinical classification of polymerase gamma (POLG) disease based on age of onset; studies using a cohort of 155 cases 

      Hikmat, Omar; Naess, Karin; Engvall, Martin; Klingenberg, Claus; Rasmussen, Magnhild; Tallaksen, Chantal; Brodtkorb, Eylert; Østergaard, Elsebet; de Coo, Irenaeus F.M.; Pias-Peleteiro, Leticia; Isohanni, Pirjo; Uusimaa, Johanna; Darin, Niklas; Rahman, Shamima; Bindoff, Laurence (Journal article; Peer reviewed, 2020)
      Background Variants in POLG are one of the most common causes of inherited mitochondrial disease. Phenotypic classification of POLG disease has evolved haphazardly making it complicated and difficult to implement in ...
    • Simultaneous bilateral aqueous misdirection following certolizumab therapy for rheumatoid arthritis 

      Hynnekleiv, Leif; Thrane, Alexander Stanley; Krohn, Jørgen (Journal article; Peer reviewed, 2020)
      Aqueous misdirection syndrome is a rare, incompletely understood, sight-threatening eye condition that is difficult to diagnose and treat. We present a case of simultaneous bilateral aqueous misdirection following the ...
    • Simultaneous Resection of Primary Colorectal Cancer and Synchronous Liver Metastases: Contemporary Practice, Evidence and Knowledge Gaps 

      Kleive, Dyre; Aas, Eline; Angelsen, Jon-Helge; Bringeland, Erling Audun; Nesbakken, Arild; Nymo, Linn Såve; Schultz, Johannes Kurt; Søreide, Kjetil; Yaqub, Sheraz (Journal article; Peer reviewed, 2021)
      The timing of surgical resection of synchronous liver metastases from colorectal cancer has been debated for decades. Several strategies have been proposed, but high-level evidence remains scarce. Simultaneous resection ...
    • Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse 

      Taavitsainen, S.; Engedal, Nikolai; Cao, S.; Handle, Florian; Erickson, A.; Prekovic, Stefan; Wetterskog, D.; Tolonen, Teemu T.; Vuorinen, E.M.; Kiviaho, A.; Nätkin, R.; Häkkinen, T.; Devlies, W.; Henttinen, S.; Kaarijärvi, R.; Lahnalampi, M.; Kaljunen, H.; Nowakowska, K.; Syvälä, H.; Bläuer, M.; Cremaschi, P.; Claessens, Frank; Visakorpi, Tapio; Tammela, T.L.J.; Murtola, T.; Granberg, K.J.; Lamb, Alastair D.; Ketola, Kirsi; Mills, Ian; Attard, Gerhardt; Wang, W.; Nykter, Matti; Urbanucci, Alfonso (Journal article; Peer reviewed, 2021)
      Prostate cancer is heterogeneous and patients would benefit from methods that stratify those who are likely to respond to systemic therapy. Here, we employ single-cell assays for transposase-accessible chromatin (ATAC) and ...
    • Six versus two weeks treatment with doxycycline in Lyme neuroborreliosis: the protocol of a multicentre, non-inferiority, double-blinded and randomised controlled trial 

      Solheim, Anne Marit; Ljøstad, Unn; Mygland, Åse (Peer reviewed; Journal article, 2019)
      Introduction: Current treatment guidelines for European Lyme neuroborreliosis (LNB) recommend cephalosporins, penicillin or doxycycline for 14–28 days but evidence for optimal treatment length is poor. Treatment lengths ...
    • Sjögren’s syndrome: studying the disease in mice 

      Delaleu, Nicolas Hervé; Nguyen, Cuong Q.; Peck, Ammon B.; Jonsson, Roland (Peer reviewed; Journal article, 2011-06-13)
      Sjögren’s syndrome (SS), a systemic autoimmune disease, is characterized by infl ammation of exocrine tissues accompanied by a signifi cant loss of their secretory function. Clinical symptoms develop late and there are no ...
    • Sjøfolks syn- har vi riktig fokus på helsekrav og undersøkelsesmetode? 

      Koefoed, Vilhelm F (Journal article, 2008)
      En vanlig synsundersøkelse måler skarpsyn, men sier ingenting om evnen til å se kontraster. Spesielt i mørke, tåke eller motlys er godt kontrastsyn vel så viktig, når man holder utkikk på broen.
    • Sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study 

      Engstrøm, Morten; Hagen, Knut; Bjørk, Marte Helene; Stovner, Lars Jacob; Gravdahl, Gøril Bruvik; Stjern, Marit; Sand, Trond (Peer reviewed; Journal article, 2013-02-14)
      Background: Our aim was to compare subjective and objective sleep quality and arousal in migraine and to evaluate the relationship between sleep quality and pain thresholds (PT) in controls, interictal, preictal and postictal ...
    • Sleep-related and non-sleep-related migraine: interictal sleep quality, arousals and pain thresholds 

      Engstrøm, Morten; Hagen, Knut; Bjørk, Marte Helene; Gravdahl, Gøril Bruvik; Sand, Trond (Peer reviewed; Journal article, 2013-08-06)
      Background: The mechanisms associating sleep and migraine are unknown. No previous polysomnographic (PSG) or pain-threshold (PT) study has compared patients with sleep-related migraine attacks (SM), non-sleep related ...
    • Social media in surgery: evolving role in research communication and beyond 

      Grossman, Rebecca; Sgarbura, Olivia; Hallet, Julie; Søreide, Kjetil (Journal article; Peer reviewed, 2021)
      Purpose To present social media (SoMe) platforms for surgeons, how these are used, with what impact, and their roles for research communication. Methods A narrative review based on a literature search regarding social ...
    • Sosiale skilnadar i kostvanar blant ungdom i Sogn og Fjordane i perioden 1997 - 2009 

      Stokstad, Janette Moland (Master thesis, 2014-05-15)
      Social disparities in health follow a gradient through the whole population, the social gradient in health. People with higher education, better occupational status and income live on average longer lives and have better ...
    • Spastic paraplegia type 7 is associated with multiple mitochondrial DNA deletions 

      Wedding, Iselin Marie; Koht, Jeanette; Tran, Gia Tuong Thi; Misceo, Doriana; Selmer, Kaja Kristine; Holmgren, Asbjørn; Frengen, Eirik; Bindoff, Laurence; Tallaksen, Chantal; Tzoulis, Charalampos (Peer reviewed; Journal article, 2014-01-22)
      Spastic paraplegia 7 is an autosomal recessive disorder caused by mutations in the gene encoding paraplegin, a protein located at the inner mitochondrial membrane and involved in the processing of other mitochondrial ...
    • Standardised data reporting from pre-hospital advanced airway management - a nominal group technique update of the Utstein-style airway template 

      Sunde, Geir Arne; Kottmann, Alexandre; Heltne, Jon-Kenneth; Sandberg, Mårten; Gellerfors, Mikael; Krüger, Andreas; Lockey, David; Sollid, Stephen J. M. (Peer reviewed; Journal article, 2018-06-04)
      Background: Pre-hospital advanced airway management with oxygenation and ventilation may be vital for managing critically ill or injured patients. To improve pre-hospital critical care and develop evidence-based guidelines, ...
    • Stem cell function is conserved during shortterm storage of cultured epidermal cell sheets at 12˚C 

      Ringstad, Håkon; Reppe, Sjur; Schøyen, Tine Hiorth; Tønseth, Kim Alexander; Utheim, Tor Paaske; Jackson, Catherine (Journal article; Peer reviewed, 2020)
      Transplantation of cultured epidermal cell sheets (CES) can be life-saving for patients with large area burns. CES have also been successfully used to regenerate eye and urethral epithelia in animal models. Short-term ...
    • Steppingstones to the implementation of an inhospital fracture and dislocation registry using the AO/OTA classification: compliance, completeness and commitment 

      Meling, Terje; Harboe, Knut; Arthursson, Astvaldur J.; Søreide, Kjetil (Peer reviewed; Journal article, 2010-10-18)
      Background Musculoskeletal trauma represents a considerable global health burden, however reliable population-based incidence data are scarce. A fracture and dislocation registry was established within a well-defined ...
    • Steroid use in elderly critically ill COVID-19 patients 

      Jung, Christian; Wernly, Bernhard; Fjølner, Jesper; Bruno, Raphael Romano; Dudzinski, David; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Jörg C.; Wolff, Georg; Kelm, Malte; Beil, Michael; Sigal, Sviri; van Heerden, Peter Vernon; Szczeklik, Wojciech; Czuczwar, Mirosław; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Zafeiridis, Tilemachos; Marsh, Brian; Andersen, Finn Husøy; Moreno, Rui; Cecconi, Maurizio; Leaver, Susannah; Boumendil, Ariane; De Lange, Dylan W.; Guidet, Bertrand; Flaatten, Hans Kristian (Journal article; Peer reviewed, 2021)
      This secondary analysis of the COVIP study shows a higher 30-day mortality in critically ill elderly COVID-19 patients who received steroids as part of their treatment
    • Stomach antral endocrine cells in patients with irritable bowel syndrome 

      El-Salhy, Magdy; Gilja, Odd Helge; Hatlebakk, Jan G; Hausken, Trygve (Peer reviewed; Journal article, 2014-10)
      To the best of our knowledge, stomach antral endocrine cells have not previously been investigated in patients with irritable bowel syndrome (IBS). Thus, in the present study, 76 patients with IBS were examined (designated ...