Browsing Department of Clinical Medicine by Title
Now showing items 1782-1801 of 2057
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Severe traumatic brain injury in Norway: Impact of age on outcome
(Peer reviewed; Journal article, 2013-04-23)Objective: The aim of this study was to investigate the influence of age on mortality and 3-month outcome in a Norwegian cohort of patients with severe traumatic brain injury (TBI). Methods: Norwegian residents ≥ 16 years ... -
Sex-specific outcome disparities in very old patients admitted to intensive care medicine: a propensity matched analysis
(Journal article; Peer reviewed, 2020)Female and male very elderly intensive patients (VIPs) might differ in characteristics and outcomes. We aimed to compare female versus male VIPs in a large, multinational collective of VIPs with regards to outcome and ... -
Sex-specific treatment characteristics and 30-day mortality outcomes of critically ill COVID-19 patients over 70 years of age—results from the prospective COVIP study
(Journal article; Peer reviewed, 2022)Purpose Older critically ill patients with COVID-19 have been the most vulnerable during the ongoing pandemic, with men being more prone to hospitalization and severe disease than women. We aimed to explore sex-specific ... -
The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis
(Journal article; Peer reviewed, 2022)Recent genome-wide association studies of mood instability (MOOD) have found significant positive genetic correlation with major depression (DEP) and weak correlations with other psychiatric disorders. We investigated the ... -
Short and long-term effects of single and multiple sessions of electroconvulsive therapy on brain gray matter volumes
(Journal article; Peer reviewed, 2021)Background: Electroconvulsive therapy (ECT) has been shown to induce broadly distributed cortical and subcortical volume increases, more prominently in the amygdala and the hippocampus. Structural changes after one ECT ... -
A short endoscopic Secretin test for the diagnosis of chronic pancreatitis
(Doctoral thesis, 2018-06-12)Background: The diagnosis of CP is not yet clearly defined. Many national guidelines exist, but - as in many other not clearly defined diseases - there is no worldwide consensus. In CP, evaluation of exocrine pancreatic ... -
Short tau inversion recovery MRI of Modic changes: a reliability study
(Journal article; Peer reviewed, 2020)Background Limited reliability data exist for evaluation of spinal edema changes on magnetic resonance imaging (MRI) with short tau inversion recovery (STIR) sequences. Purpose To assess the inter-observer reliability ... -
Short-term effects of Vertical sleeve gastrectomy and Roux-en-Y gastric bypass on glucose homeostasis
(Peer reviewed; Journal article, 2019-10-15)The objective of this study was to compare the biochemical changes related to glucose tolerance and lipid metabolism in non-diabetic patients shortly after vertical sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB). ... -
The short-term impact of methylprednisolone on patient-reported sleep in patients with advanced cancer in a randomized, placebo-controlled, double-blind trial
(Journal article; Peer reviewed, 2020)Purpose: Although corticosteroids are frequently used in patients with advanced cancer, few studies have examined the impact of these drugs on patient-reported sleep. We aimed to examine the short-term impact of ... -
Short-term outcome of 1,465 computer-navigated primary total knee replacements 2005–2008. A report from the Norwegian Arthroplasty Register
(Peer reviewed; Journal article, 2011-06)Background and purpose: Improvement of positioning and alignment by the use of computer-assisted surgery (CAS) might improve longevity and function in total knee replacements, but there is little evidence. In this study, ... -
Shoulder instability surgery in Norway. The first report from a multicenter register, with 1-year follow-up
(Peer reviewed; Journal article, 2011-11-23)Background and purpose. In January 2008, we established the Norwegian Register for Shoulder Instability Surgery. We report on the establishment, the baseline data, and the results at 1-year follow-up. Methods. Primary and ... -
Similar early mortality risk after cemented compared with cementless total hip arthroplasty for primary osteoarthritis: data from 188,606 surgeries in the Nordic Arthroplasty Register Association database
(Journal article; Peer reviewed, 2021)Background and purpose — Current literature indicates no difference in 90-day mortality after cemented compared with cementless total hip arthroplasty (THA). However, previous studies are hampered by potential selection ... -
Similar migration in computer-assisted and conventional total knee arthroplasty
(Peer reviewed; Journal article, 2017)Background and purpose — Computer-assisted surgery (CAS) in total knee arthroplasty (TKA) has been used in recent years in the hope of improving the alignment and positioning of the implant, thereby achieving a better ... -
Similarly low-blood metal ion levels at 10-years follow-up of total hip arthroplasties with Oxinium, CoCrMo, and stainless steel femoral heads. Data from a randomized clinical trial
(Journal article; Peer reviewed, 2022)The use of inert head materials such as ceramic heads has been proposed as a method of reducing wear and corrosion products from the articulating surfaces in total hip arthroplasty, as well as from the stem-head taper ... -
Simple limbal epithelial transplantation: Current status and future perspectives
(Peer reviewed; Journal article, 2019-12-04)Damage to limbal stem cells as a result of injury or disease can lead to limbal stem cell deficiency (LSCD). This disease is characterized by decreased vision that is often painful and may progress to blindness. Clinical ... -
A simple versatile solution for collecting multidimensional clinical data based on the CakePHP web application framework
(Peer reviewed; Journal article, 2014-04)Clinical trials aiming for regulatory approval of a therapeutic agent must be conducted according to Good Clinical Practice (GCP). Clinical Data Management Systems (CDMS) are specialized software solutions geared toward ... -
Simplifying the clinical classification of polymerase gamma (POLG) disease based on age of onset; studies using a cohort of 155 cases
(Journal article; Peer reviewed, 2020)Background Variants in POLG are one of the most common causes of inherited mitochondrial disease. Phenotypic classification of POLG disease has evolved haphazardly making it complicated and difficult to implement in ... -
Simulation-based team-training in acute stroke: Is it safe to speed up?
(Journal article; Peer reviewed, 2022)Background In acute ischemic stroke (AIS), rapid treatment with intravenous thrombolysis (IVT) is crucial for good clinical outcome. Weekly simulation-based team-training of the stroke treatment team was implemented, ... -
Simultaneous bilateral aqueous misdirection following certolizumab therapy for rheumatoid arthritis
(Journal article; Peer reviewed, 2020)Aqueous misdirection syndrome is a rare, incompletely understood, sight-threatening eye condition that is difficult to diagnose and treat. We present a case of simultaneous bilateral aqueous misdirection following the ...