Browsing Department of Clinical Medicine by Document Types "Journal article"
Now showing items 1-20 of 1075
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An 18-Gene signature for vascular invasion is associated with aggressive features and reduced survival in breast cancer
(Peer reviewed; Journal article, 2014-06-06)Aims: Vascular invasion by tumor cells is known to be important for cancer progression. By microarray and qPCR analyses, we earlier identified an 18-gene signature associated with vascular involvement in endometrial cancer. ... -
A 60-year follow-up of the incidence and prevalence of multiple sclerosis in Hordaland County, Western Norway
(Peer reviewed; Journal article, 2015-01-14)Objective: Investigate the incidence of multiple sclerosis during 1953–2013 and estimate the prevalence rate of MS on 1 January 2003 and 2013 in Hordaland County, Western Norway. Methods: All patients with onset of disease ... -
Abnormal Uroguanylin Immunoreactive Cells Density in the Duodenum of Patients with Diarrhea-Predominant Irritable Bowel Syndrome Changes following Fecal Microbiota Transplantation
(Journal article; Peer reviewed, 2020)Altered densities of enteroendocrine cells play an important role in patients with irritable bowel syndrome (IBS). Uroguanylin activates guanylate cyclase-C to regulate intestinal electrolyte and water transport. Aim. To ... -
Accounting for symptom heterogeneity can improve neuroimaging models of antidepressant response after electroconvulsive therapy
(Journal article; Peer reviewed, 2021)Depression symptom heterogeneity limits the identifiability of treatment-response biomarkers. Whether improvement along dimensions of depressive symptoms relates to separable neural networks remains poorly understood. We ... -
Accumulation dynamics of transcripts and proteins of cold-responsive genes in fragaria vesca genotypes of differing cold tolerance
(Journal article; Peer reviewed, 2021)Identifying and characterizing cold responsive genes in Fragaria vesca associated with or responsible for low temperature tolerance is a vital part of strawberry cultivar development. In this study we have investigated the ... -
Accumulation of Globotriaosylceramide in Podocytes in Fabry Nephropathy Is Associated with Progressive Podocyte Loss
(Journal article; Peer reviewed, 2020)Background In males with classic Fabry disease, the processes leading to the frequent outcome of ESKD are poorly understood. Defects in the gene encoding α-galactosidase A lead to accumulation of globotriaosylceramide (GL3) ... -
Accuracy of surgical complication rate estimation using ICD-10 codes
(Peer reviewed; Journal article, 2019-02)Background: The ICD‐10 codes are used globally for comparison of diagnoses and complications, and are an important tool for the development of patient safety, healthcare policies and the health economy. The aim of this ... -
AChR antibodies show a complex interaction with human skeletal muscle cells in a transcriptomic study
(Journal article; Peer reviewed, 2020-07-08)Acetylcholine receptor (AChR) antibodies are the most important pathogenic marker in patients with myasthenia gravis (MG). The antibodies bind to AChRs on the postsynaptic membrane, and this leads to receptor degradation, ... -
Actigraphic assessment of motor activity in acutely admitted inpatients with bipolar disorder
(Peer reviewed; Journal article, 2014-02-20)Introduction: Mania is associated with increased activity, whereas psychomotor retardation is often found in bipolar depression. Actigraphy is a promising tool for monitoring phase shifts and changes following treatment ... -
Actigraphic registration of motor activity reveals a more structured behavioural pattern in schizophrenia than in major depression
(Peer reviewed; Journal article, 2010-05-27)Background: Disturbances in motor activity pattern are seen in both schizophrenia and depression. However, this activity has rarely been studied objectively. The purpose of the present study has been to study the complexity ... -
Actigraphy as an objective intra‑individual marker of activity patterns in acute‑phase bipolar disorder: a case series
(Peer reviewed; Journal article, 2018-03-07)Background: Actigraphy could be an objective alternative to clinical ratings of motor activity in bipolar disorder (BD), which is of importance now that increased activity and energy are added as cardinal symptoms of ... -
Actigraphy assessment of motor activity and sleep in patients with alcohol withdrawal syndrome and the effects of intranasal oxytocin
(Journal article; Peer reviewed, 2020)Background and aims The alcohol withdrawal syndrome increases autonomic activation and stress in patients during detoxification, leading to alterations in motor activity and sleep irregularities. Intranasal oxytocin has ... -
Acute complications of spinal cord injuries
(Peer reviewed; Journal article, 2015)The aim of this paper is to give an overview of acute complications of spinal cord injury (SCI). Along with motor and sensory deficits, instabilities of the cardiovascular, thermoregulatory and broncho-pulmonary system are ... -
Acute effect of a cod protein hydrolysate on postprandial acylated ghrelin concentration and sensations associated with appetite in healthy subjects: a double-blind crossover trial
(Peer reviewed; Journal article, 2019-10-22)Background: Fish protein hydrolysates are suggested to contain bioactive sequences capable of affecting metabolic pathways involved in the regulation of glucose metabolism and body weight when consumed in low doses. ... -
Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat
(Peer reviewed; Journal article, 2011-07-12)This study aims to investigate whether orexigenic antipsychotic drugs may induce dyslipidemia and glucose disturbances in female rats through direct perturbation of metabolically active peripheral tissues, independent of ... -
Acute effects of whey protein on energy intake, appetite and gastric emptying in younger and older, obese men
(Journal article; Peer reviewed, 2020)Background Obesity is becoming more prevalent in older people. A management strategy in obese, young adults is to increase dietary protein relative to other macronutrients. It is not clear if this is effective in obese, ... -
Acute elevation of intra-abdominal pressure contributes to extravascular shift of fluid and proteins in an experimental porcine model
(Peer reviewed; Journal article, 2014-10-20)Background: Intra-abdominal hypertension and abdominal compartment syndrome contribute significantly to increased morbidity and mortality in critically ill patients. This study describes pathophysiologic effects of the ... -
Acute kidney injury in burn patients admitted to the intensive care unit: a systematic review and meta-analysis
(Peer reviewed; Journal article, 2020-01-02)Background: Acute kidney injury (AKI) is a common complication in burn patients admitted to the intensive care unit (ICU) associated with increased morbidity and mortality. Our primary aim was to review incidence, risk ... -
ADCK3 mutations with epilepsy, stroke-like episodes and ataxia: a POLG mimic?
(Peer reviewed; Journal article, 2016-07)Background and purpose: Defects of coenzyme Q10 (CoQ10) metabolism cause a variety of disorders ranging from isolated myopathy to multisystem involvement. ADCK3 is one of several genes associated with CoQ10 deficiency that ... -
Addition of eGFR and age improves the prognostic absolute renal risk-model in 1,134 norwegian patients with IgA nephropathy
(Peer reviewed; Journal article, 2015-05)Background: Predicting outcome in individual patients with IgA nephropathy (IgAN) is difficult but important. For this purpose, the absolute renal risk (ARR) model has been developed in a French cohort to calculate the ...