• Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight 

      Küpers, Leanne K.; Monnereau, Claire; Sharp, Gemma C.; Yousefi, Paul; Salas, Lucas A.; Ghantous, Akram; Page, Christian Magnus; Reese, Sarah E.; Wilcox, Allen J.; Czamara, Darina; Starling, Anne P.; Novoloaca, Alexei; Lent, Samantha; Roy, Ritu; Hoyo, Cathrine; Breton, Carrie V.; Allard, Catherine; Just, Allan C.; Bakulski, Kelly M.; Holloway, John W.; Everson, Todd M.; Xu, Cheng-Jian; Huang, Rae-Chi; van der Plaat, Diana A.; Wielscher, Matthias; Merid, Simon Kebede; Ullemar, Vilhelmina; Rezwan, Faisal I.; Lahti, Jari; van Dongen, Jenny; Langie, Sabine A.S.; Richardson, Tom G.; Magnus, Maria Christine; Nohr, Ellen A.; Xu, Zongli; Duijts, Liesbeth; Zhao, Shanshan; Zhang, Weiming; Plusquin, Michelle; DeMeo, Dawn L.; Solomon, Olivia; Heimovaara, Joosje H.; Jima, Dereje D.; Gao, Lu; Bustamante, Mariona; Perron, Patrice; Wright, Robert O.; Hertz-Picciotto, Irva; Zhang, Hongmei; Karagas, Margaret R.; Gehring, Ulrike; Marsit, Carmen J.; Beilin, Lawrence J.; Vonk, Judith M.; Jarvelin, Marjo-Riitta; Bergström, Anna; Örtqvist, Anne K.; Ewart, Susan; Villa, Pia M.; Moore, Sophie E.; Willemsen, Gonneke; Standaert, Arnout R.L.; Håberg, Siri Eldevik; Sørensen, Thorkild I.A.; Taylor, Jack A.; Räikkönen, Katri; Yang, Ivana V.; Kechris, Katerina; Nawrot, Tim S.; Silver, Matt J.; Gong, Yun Yun; Richiardi, Lorenzo; Kogevinas, Manolis; Litonjua, Augusto A.; Eskenazi, Brenda; Huen, Karen; Mbarek, Hamdi; Maguire, Rachel L.; Dwyer, Terence; Vrijheid, Martine; Bouchard, Luigi; Baccarelli, Andrea A.; Croen, Lisa A.; Karmaus, Wilfried; Anderson, Denise; de Vries, Maaike; Sebert, Sylvain; Kere, Juha; Karlsson, Robert; Arshad, Syed Hasan; Hämäläinen, Esa; Routledge, Michael N.; Boomsma, Dorret I.; Feinberg, Andrew P.; Newschaffer, Craig J.; Govarts, Eva; Moisse, Matthieu; Fallin, M. Daniele; Melén, Erik; Prentice, Andrew M.; Kajantie, Eero; Almqvist, Catarina; Oken, Emily; Dabelea, Dana; Boezen, H. Marike; Melton, Philip E.; Wright, Rosalind J.; Koppelman, Gerard H.; Trevisi, Letizia; Hivert, Marie-France; Sunyer, Jordi; Munthe-Kaas, Monica Cheng; Murphy, Susan K.; Corpeleijn, Eva; Wiemels, Joseph L.; Holland, Nina; Herceg, Zdenko; Binder, Elisabeth B.; Davey Smith, George; Jaddoe, Vincent V.W.; Lie, Rolv T.; Nystad, Wenche; London, Stephanie J.; Lawlor, Debbie A.; Relton, Caroline L.; Snieder, Harold; Felix, Janine F. (Peer reviewed; Journal article, 2019-04-23)
      Birthweight is associated with health outcomes across the life course, DNA methylation may be an underlying mechanism. In this meta-analysis of epigenome-wide association studies of 8,825 neonates from 24 birth cohorts in ...
    • Narcolepsy and hypersomnia in Norwegian children and young adults following the influenza A(H1N1) 2009 pandemic 

      Trogstad, Lill; Bakken, Inger Johanne; Gunnes, Nina; Ghaderi, Sara; Stoltenberg, Camilla; Magnus, Per; Håberg, Siri Eldevik (Peer reviewed; Journal article, 2017-04)
      Background: Associations between influenza infection and sleep disorders are poorly studied. We investigated if pandemic influenza infection or vaccination with Pandemrix in 2009/2010 was associated with narcolepsy or ...
    • Nasjonale registerkilder i epidemiologisk forskning 

      Håberg, Siri Eldevik; Ebbing, Marta; Stoltenberg, Camilla (Peer reviewed; Journal article, 2017)
    • Neuraminidase inhibitors during pregnancy and risk of adverse neonatal outcomes and congenital malformations: population based European register study 

      Graner, Sophie; Svensson, Tobias; Beau, Anna-Belle; Damase-Michel, Christine; Engeland, Anders; Furu, Kari; Hviid, Anders; Håberg, Siri Eldevik; Mølgaard-Nielsen, Ditte; Pasternak, Björn; Kieler, Helle (Peer reviewed; Journal article, 2017)
      Objective: To evaluate the possible effects of exposure to neuraminidase inhibitors during embryo-fetal life with respect to adverse neonatal outcomes and congenital malformations. Design: Population based multinational ...
    • Nucleated red blood cells explain most of the association between DNA methylation and gestational age 

      Haftorn, Kristine Løkås; Denault, William Robert Paul; Lee, Yunsung; Page, Christian Magnus; Romanowska, Julia; Lyle, Robert; Næss, Øyvind Erik; Kristjansson, Dana; Magnus, Per Minor; Håberg, Siri Eldevik; Bohlin, Jon; Jugessur, Astanand (Journal article; Peer reviewed, 2023)
      Determining if specific cell type(s) are responsible for an association between DNA methylation (DNAm) and a given phenotype is important for understanding the biological mechanisms underlying the association. Our EWAS of ...
    • Paternal and maternal birthweight and offspring risk of macrosomia at term gestations: A nationwide population study 

      Rasmussen, Svein; Carlsen, Ellen Øen; Linde, Lorentz; Morken, Nils-Halvdan; Håberg, Siri Eldevik; Ebbing, Cathrine (Journal article; Peer reviewed, 2023)
      Background There is a paucity of data on whether parents' macrosomia (birthweight ≥4500 g) status influences the risk of macrosomia in the offspring. The role of maternal overweight in the generational effect of macrosomia ...
    • Pregnancy and risk of COVID-19: a Norwegian registry-linkage study 

      Magnus, Maria Christine; Oakley, Laura L.; Gjessing, Håkon K.; Stephansson, Olof; Engjom, Hilde Marie; Macsali, Ferenc; Juliusson, Pétur Benedikt; Nybo Andersen, Anne-Marie; Håberg, Siri Eldevik (Journal article; Peer reviewed, 2021)
      Objective: To compare the risk of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and contact with specialist healthcare services for coronavirus disease 2019 (COVID-19) between pregnant and non-pregnant ...
    • Prevalence and predictors of post-COVID-19 symptoms in general practice - a registry-based nationwide study 

      Hetlevik, Øystein; Wensaas, Knut-Arne; Baste, Valborg; Emberland, Knut Erik; Özgümüs, Türküler; Håberg, Siri Eldevik; Rørtveit, Guri (Journal article; Peer reviewed, 2023)
      Background With Norwegian national registry data, we assessed the prevalence of post-COVID-19 symptoms at least 3 months after confirmed infection, and whether sociodemographic factors and pre-pandemic health problems were ...
    • Risk of miscarriage in women with psychiatric disorders 

      Magnus, Maria Christine; Havdahl, Alexandra; Morken, Nils-Halvdan; Wensaas, Knut-Arne; Wilcox, Allen J.; Håberg, Siri Eldevik (Journal article; Peer reviewed, 2021)
      Background Some psychiatric disorders have been associated with increased risk of miscarriage. However, there is a lack of studies considering a broader spectrum of psychiatric disorders to clarify the role of common as ...
    • Risk of stroke the year following a delivery after using assisted reproductive technologies 

      Magnus, Maria Christine; Håberg, Siri Eldevik; Rönö, Kristiina; Romundstad, Liv Bente Bergem; Bergh, Christina; Spangmose, Anne Lærke; Pinborg, Anja; Gissler, Mika; Wennerholm, Ulla-Britt; Opdahl, Signe (Journal article; Peer reviewed, 2023)
      Background Studies indicate that individuals who deliver after assisted reproductive technologies (ART) may have an increased risk of cardiovascular disease (CVD). A recent large study from the U.S. showed a higher risk ...
    • Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study 

      Magnus, Maria Christine; Wilcox, Allen J; Morken, Nils-Halvdan; Weinberg, Clarice R.; Håberg, Siri Eldevik (Peer reviewed; Journal article, 2019)
      Objectives: To estimate the burden of miscarriage in the Norwegian population and to evaluate the associations with maternal age and pregnancy history. Design: Prospective register based study. Setting: Medical Birth ...
    • Seasonal and pandemic influenza during pregnancy and risk of fetal death: A Norwegian registry‑based cohort study 

      Gunnes, Nina; Gjessing, Håkon K.; Bakken, Inger Johanne Landsjøåsen; Ghaderi, Sara; Gran, Jon Michael; Hungnes, Olav; Magnus, Per; Samuelsen, Sven Ove; Skrondal, Anders; Stoltenberg, Camilla; Trogstad, Lill; Wilcox, Allen James; Håberg, Siri Eldevik (Journal article; Peer reviewed, 2020)
      Previous studies of fetal death with maternal influenza have been inconsistent. We explored the effect of maternal influenza-like illness (ILI) in pregnancy on the risk of fetal death, distinguishing between diagnoses ...
    • Stability selection enhances feature selection and enables accurate prediction of gestational age using only five DNA methylation sites 

      Haftorn, Kristine Løkås; Romanowska, Julia; Lee, Yunsung; Page, Christian Magnus; Magnus, Per Minor; Håberg, Siri Eldevik; Bohlin, Jon; Jugessur, Astanand; Denault, William Robert Paul (Journal article; Peer reviewed, 2023)
      Background: DNA methylation (DNAm) is robustly associated with chronological age in children and adults, and gestational age (GA) in newborns. This property has enabled the development of several epigenetic clocks that can ...
    • Statistical methods to detect mother-father genetic interaction effects on risk of infertility: A genome-wide approach 

      Skodvin, Siri Nærland; Gjessing, Håkon Kristian; Jugessur, Astanand; Romanowska, Julia; Page, Christian Magnus; Corfield, Elizabeth Claire; Lee, Yunsung; Håberg, Siri Eldevik; Gjerdevik, Miriam (Journal article; Peer reviewed, 2023)
      Infertility is a heterogeneous phenotype, and for many couples, the causes of fertility problems remain unknown. One understudied hypothesis is that allelic interactions between the genotypes of the two parents may influence ...
    • Two age peaks in the incidence of chronic fatigue syndrome/myalgic encephalomyelitis: a population-based registry study from Norway 2008-2012 

      Bakken, Inger Johanne; Tveito, Kari; Gunnes, Nina; Ghaderi, Sara; Stoltenberg, Camilla; Trogstad, Lill; Håberg, Siri Eldevik; Magnus, Per (Peer reviewed; Journal article, 2014-10-01)
      Background: The aim of the current study was to estimate sex- and age-specific incidence rates of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) using population-based registry data. CFS/ME is a debilitating ...
    • Vanishing twin syndrome among ART singletons and pregnancy outcomes 

      Magnus, Maria Christine; Ghaderi, Sara; Morken, Nils-Halvdan; Magnus, Per; Romundstad, Liv Bente Bergem; Skjaerven, Rolv; Wilcox, Allen J; Håberg, Siri Eldevik (Peer reviewed; Journal article, 2017-11)
      STUDY QUESTION: Among babies born by ART, do singleton survivors of a vanishing twin have lower birth weight than other singletons? SUMMARY ANSWER: Vanishing twin syndrome (VTS) was associated with lower birth weight among ...
    • The X-factor in ART: does the use of assisted reproductive technologies influence DNA methylation on the X chromosome? 

      Romanowska, Julia; Nustad, Haakon Egdetveit; Page, Christian Magnus; Denault, William Robert Paul; Lee, Yunsung; Magnus, Maria Christine; Haftorn, Kristine Løkås; Gjerdevik, Miriam; Novakovic, Boris; Saffery, Richard; Gjessing, Håkon K.; lyle, robert; Magnus, Per Minor; Håberg, Siri Eldevik; Jugessur, Astanand (Journal article; Peer reviewed, 2023)
      Background Assisted reproductive technologies (ART) may perturb DNA methylation (DNAm) in early embryonic development. Although a handful of epigenome-wide association studies of ART have been published, none have investigated ...