Browsing Faculty of Medicine by Title
Now showing items 6955-6974 of 8761
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Randomized Controlled Trial of Extended Perioperative Counseling in Enhanced Recovery After Colorectal Surgery
(Peer reviewed; Journal article, 2018-06)BACKGROUND: Enhanced recovery after surgery programs reduce the length of hospital stay in patients who undergo elective colorectal resection, but the reasons for this reduction are not well understood. OBJECTIVE: The aim ... -
Randomized controlled trial of the effectiveness of three different oral moisturizers in palliative care patients
(Peer reviewed; Journal article, 2019-12)Most patients in palliative care have problems with dry mouth caused by medication or as a direct result of their condition. Dry mouth may cause problems that affect the primary disease negatively and contribute to poorer ... -
A randomized controlled trial with bright light and melatonin for treatment of delayed sleep phase disorder. Effects on subjective and objective sleepiness and cognitive function.
(Peer reviewed; Journal article, 2013-10)Delayed sleep phase disorder (DSPD) is a circadian rhythm sleep disorder. Patients with DSPD have problems initiating sleep if they go to bed at a conventional time and they often have problems waking at desired times. If ... -
Randomized controlled trials and alternative study designs in surgical oncology
(Journal article; Peer reviewed, 2023)Surgery is central to the cure of most solid cancers and an integral part of modern multimodal cancer management for early and advanced stage cancers. Decisions made by surgeons and multidisciplinary team members are based ... -
A randomized double blind comparison of short-term duodenally administrated whale and seal blubber oils in patients with inflammatory bowel disease and joint pain
(Peer reviewed; Journal article, 2009)Compared with soy oil, 10 days treatment with seal oil (SO), 10 mL×3 daily, self-administrated through a nasoduodenal feeding tube, relieves joint pain in patients with inflammatory bowel disease (IBD). This randomized, ... -
Randomized implementation of a primary human papillomavirus testing-based cervical cancer screening protocol for women 34 to 69 years in Norway
(Journal article; Peer reviewed, 2022)Background: Cervical cancer screening programs are facing a programmatic shift where screening protocol based on human papillomavirus testing (HPV-Screening protocol) is replacing the liquid-based cytology (LBC-Screening ... -
A randomized phase II pre-surgical trial of weekly low-dose tamoxifen versus raloxifene versus placebo in premenopausal women with estrogen receptor positive breast cancer
(Peer reviewed; Journal article, 2013-06-20)Introduction: We previously demonstrated that 1 or 5 mg per day of tamoxifen (T) given for four weeks before surgery reduces Ki-67 in breast cancer (BC) patients to the same extent as the standard 20 mg/d. Given the long ... -
A randomized study on migration of the Spectron EF and the Charnley flanged 40 cemented femoral components using radiostereometric analysis at 2 years
(Peer reviewed; Journal article, 2011-10)Background and purpose: We performed a randomized study to determine the migration patterns of the Spectron EF femoral stem and to compare them with those of the Charnley stem, which is regarded by many as the gold standard ... -
A randomized study on migration of the Spectron EF and the Charnley flanged 40 cemented femoral components using radiostereometric analysis at 2 years
(Peer reviewed; Journal article, 2011-11-24)Background and purpose: We performed a randomized study to determine the migration patterns of the Spectron EF femoral stem and to compare them with those of the Charnley stem, which is regarded by many as the gold standard ... -
A randomized trial of laryngeal mask airway in neonatal resuscitation
(Journal article; Peer reviewed, 2020)Background: Face-mask ventilation is the most common resuscitation method for birth asphyxia. Ventilation with a cuffless laryngeal mask airway (LMA) has potential advantages over face-mask ventilation during neonatal ... -
A randomized trial to determine the impact of indacaterol/glycopyrronium on nighttime oxygenation and symptoms in patients with moderate-to-severe COPD: The DuoSleep study
(Peer reviewed; Journal article, 2019-01-09)Purpose: This study investigated the effect of dual bronchodilation with the long-acting β-receptor agonist/long-acting muscarinic antagonist combination, indacaterol/glycopyrronium (IND/GLY), on nighttime oxygenation, ... -
A randomized, double-blind, placebo-controlled clinical study to investigate the efficacy of herring roe oil for treatment of psoriasis
(Journal article; Peer reviewed, 2020-05-07)The effect of omega-3 polyunsaturated fatty acid supplements in patients with psoriasis vulgaris has previously been investigated, but interventions varied in source, composition, dose, administration route and duration ... -
Rapid adherence to collagen IV enriches for tumour initiating cells in oral cancer.
(Peer reviewed; Journal article, 2014-12)Background: Although several approaches for identification and isolation of carcinoma cells with tumour initiating properties have been established, enrichment of a population of pure and viable tumour-initiating cells ... -
Rapid and Specific Diagnosis of Extrapulmonary Tuberculosis by Immunostaining of Tissues and Aspirates With Anti-MPT64
(Peer reviewed; Journal article, 2017-04)Background: Extrapulmonary tuberculosis (EPTB) constitutes about 15% to 20% of all cases of tuberculosis (TB). The confirmation of EPTB has always been a challenge to laboratory personnel. We aim to evaluate the diagnostic ... -
A rapid antibody screening haemagglutination test for predicting immunity to SARS-CoV-2 variants of concern
(Journal article; Peer reviewed, 2022)Background: Evaluation of susceptibility to emerging SARS-CoV-2 variants of concern (VOC) requires rapid screening tests for neutralising antibodies which provide protection. Methods: Firstly, we developed a receptor-binding ... -
Rapid genotyping of the human renin (REN) gene by the LightCycler® instrument: Identification of unexpected nucleotide substitutions within the selected hybridization probe area
(Peer reviewed; Journal article, 2010)Preeclampsia is a serious disorder affecting nearly 3% of all in the Western world. It is associated with hypertension and proteinuria, and several lines of evidence suggest that the renin-angiotensin system (RAS) may be ... -
Rapid syndromic PCR testing in patients with respiratory tract infections reduces time to results and improves microbial yield
(Journal article; Peer reviewed, 2022)Lack of rapid and comprehensive microbiological diagnosis in patients with community acquired pneumonia (CAP) hampers appropriate antimicrobial therapy. This study evaluates the real-world performance of the BioFire FilmArray ... -
Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity
(Peer reviewed; Journal article, 2019)The translation initiation repressor 4E-BP2 is deamidated in the brain on asparagines N99/N102 during early postnatal brain development. This post-translational modification enhances 4E-BP2 association with Raptor, a central ... -
A Rare Case of Unilateral Renal Cortical Necrosis
(Journal article; Peer reviewed, 2021)Unilateral cortical necrosis is a rare condition, and only described in a few case reports. We present a case of a previously healthy 24-year-old male with acute unilateral cortical necrosis, where contrast-enhanced ...