Blar i Faculty of Medicine på tittel
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The role of pyruvate dehydrogenase kinases (PDKs) in rewiring of cell metabolism under energy stress
(Master thesis, 2019-06-28)Irregularities in cellular energy metabolism have been linked to many human diseases, including metabolic disorders, mitochondrial diseases, cancer, and neurodegeneration. In order to survive and function properly, an ... -
Role of rare HNF1A variants function in monogenic and type 2 diabetes
(Doctoral thesis, 2018-10-26)Variants in the transcription factor gene HNF1A have been identified in subjects with maturity-onset diabetes of the young (MODY) type 3, type 2 diabetes, as well as in children with apparent type 1 diabetes. One of the ... -
Role of RvD1 on Osteogenic Factors Involved in the Inflammatory and Resolution Processes in Periodontal Periapical Lesions
(Master thesis, 2015-05-29)Introduction: Inflammation is a protective body response against invading traumatic or microbial injury. However, persistent or unresolved acute inflammation can result in a chronic injury to local tissues that may lead ... -
Role of SNAREs and Rabs in Myelin Regulation
(Journal article; Peer reviewed, 2023-06-05)The myelin sheath is an insulating layer around the nerves of the brain and spinal cord which allows a fast and efficient nerve conduction. Myelin is made of protein and fatty substances and gives protection for the ... -
Role of stem cells in regenerative treatment of dry eye disease caused by lacrimal gland dysfunction
(Journal article; Peer reviewed, 2022)An ageing population and increased screen use in younger people have contributed to a rise in incidence of dry eye disease (DED). Quality of life can be significantly affected by DED, with patients experiencing eye dryness, ... -
The role of the intermediate compartment in membrane traffic during different stages of the cell cycle
(Master thesis, 2011-06-01)The biosynthetic-secretory pathway delivers newly synthesized molecules from the endoplasmic reticulum (ER) to the plasma membrane (PM), as well as to endomembrane compartments. The intermediate compartment (IC) is an ... -
Role of the Neutral Amino Acid Transporter SLC7A10 in Adipocyte Lipid Storage, Obesity and Insulin Resistance
(Journal article; Peer reviewed, 2021)Elucidation of mechanisms that govern lipid storage, oxidative stress, and insulin resistance may lead to improved therapeutic options for type 2 diabetes and other obesity-related diseases. Here, we find that adipose ... -
Role of three dimensional (3D) printing in endourology: An update from EAU young academic urologists (YAU) urolithiasis and endourology working group
(Journal article; Peer reviewed, 2022)The management of nephrolithiasis has been complemented well by modern technological advancements like virtual reality, three-dimensional (3D) printing etc. In this review, we discuss the applications of 3D printing in ... -
The role of welfare regimes in the relationship between childhood economic stress and adult health: a multilevel study of 20 European countries
(Journal article; Peer reviewed, 2020)Childhood economic conditions are important for adult health, and welfare regimes may modify this relationship by altering exposure to social determinants of health. We examine the association between childhood economic ... -
Roles and responsibilities of clinical ethics committees in priority setting
(Peer reviewed; Journal article, 2017-12-01)Background: Fair prioritization of healthcare resources has been on the agenda for decades, but resource allocation dilemmas in clinical practice remain challenging. Can clinical ethics committees (CECs) be of help? The ... -
The Roles of EXT-Like Proteins in Heparan Sulphate Biosynthesis
(Doctoral thesis, 2011-02-11)Heparan sulphate (HS) proteoglycans, composed of a core protein and one or more negatively charged HS chains, are a major component of extracellular matrices and are located on the plasma membrane of all animal cells. The ... -
Roles of Myosin Va and Rab3D in Membrane Remodeling of Immature Secretory Granules
(Peer reviewed; Journal article, 2010-12-22)Neuroendocrine secretory granules (SGs) are formed at the trans-Golgi network (TGN) as immature intermediates. In PC12 cells, these immature SGs (ISGs) are transported within seconds to the cell cortex, where they move ... -
Rolleutvidelse ved noen bildediagnostiske avdelinger i Norge. En kvalitativ studie av 4 profesjoners erfaringer
(Master thesis, 2013-05-14)Bakgrunn: I januar 2009 ble Norges første radiografer med videreutdanning i ultralyd (RVU) uteksaminert ved Høgskolen i Gjøvik(HIG). Tre bildediagnostiske avdelinger har i dag RVUer som ukentlig utfører ultralydundersøkelser ... -
The Romberg sign, unilateral vestibulopathy, cerebrovascular risk factors, and long-term mortality in dizzy patients
(Journal article; Peer reviewed, 2022)Objectives: Describe the relationship between unsteadiness, canal paresis, cerebrovascular risk factors, and long-term mortality in patients examined for dizziness of suspected vestibular origin. Study design: Observational ... -
Root resorption after leveling with super-elastic and conventional steel arch wires: a prospective study
(Peer reviewed; Journal article, 2014-05-15)Background: The aim of this prospective study was to compare root resorption after the leveling phase of treatment, performed by either super-elastic or conventional multi-stranded stainless steel arch wires. Methods: From ... -
Rosuvastatin alters the genetic composition of the human gut microbiome
(Journal article; Peer reviewed, 2020)The gut microbiome contributes to the variation of blood lipid levels, and secondary bile acids are associated with the effect of statins. Yet, our knowledge of how statins, one of our most common drug groups, affect the ... -
Routine assessment of Patient-Reported Outcome Measures (PROMs) in the DiaPROM trial
(Conference poster, 2019)Objective: We aimed to investigate willingness to complete patient-reported outcome measures (PROMs) on a touchscreen computer in the outpatient clinics’ waiting area, estimate the proportion of participants with elevated ... -
Rules and regulations for a pregnant endourologist: the European perspective
(Journal article; Peer reviewed, 2021)Introduction Working in surgery while pregnant is challenging. Navigating this period safely is of paramount importance. Anecdotal observation suggests that there exists great variation among European nations in regard ... -
Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations
(Journal article; Peer reviewed, 2020-06-04)Alpha defensins are anti-microbial peptides of the innate immune system. The defensin A1 and A3 genes are located in a repeat array of variable copy number (the DEFA1A3 locus) and encode the human neutrophil peptides 1, 2 ... -
Rural general practice staff experiences of patient safety incidents and low quality of care in Norway: an interview study
(Journal article; Peer reviewed, 2022)Background and objectives General practitioners (GPs), nurses and medical secretaries (practice staff) are responsible for the continuous provision of safe care in rural general practice. Little is known about their role ...