Blar i Faculty of Medicine på tittel
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Accurate 3-gene-signature for early diagnosis of liposarcoma progression
(Journal article; Peer reviewed, 2020)Background Well- and dedifferentiated liposarcoma (WD/DDLPS) are rare mesenchymal malignant tumors that account for 20% of all sarcomas in adults. The WD form is a low-grade malignancy with a favourable prognosis which ... -
Accurate and fast neonatal heart rate assessment with a smartphone‐based application – a manikin study
(Peer reviewed; Journal article, 2018-03-31)Aim: This study determined the accuracy and speed of the NeoTapLifeSupport (NeoTapLS), a free smartphone application that aims to assess a neonate's heart rate. Methods: We asked 30 participants with a variety of backgrounds ... -
Accurate population-based model for individual prediction of colon cancer recurrence
(Journal article; Peer reviewed, 2021)Background Prediction models are useful tools in the clinical management of colon cancer patients, particularly when estimating the recurrence rate and, thus, the need for adjuvant treatment. However, the most used models ... -
Acetaminophen use during pregnancy and offspring attention deficit hyperactivity disorder - a longitudinal sibling control study
(Journal article, 2021)Background: Maternal acetaminophen use during pregnancy is associated with increased risk of ADHD in the child. This could reflect causal influence of acetaminophen on fetal neurodevelopment or could be due to confounding ... -
Achieving progress in maternal and neonatal health through integrated and comprehensive healthcare services - experiences from a programme in northern Tanzania
(Peer reviewed; Journal article, 2009-07-30)Background: An integrated and comprehensive hospital/community based health programme is presented, aimed at reducing maternal and child mortality and morbidity. It is run as part of a general programme of health care at ... -
AChR antibodies show a complex interaction with human skeletal muscle cells in a transcriptomic study
(Journal article; Peer reviewed, 2020-07-08)Acetylcholine receptor (AChR) antibodies are the most important pathogenic marker in patients with myasthenia gravis (MG). The antibodies bind to AChRs on the postsynaptic membrane, and this leads to receptor degradation, ... -
ACL Reconstruction Patients Have Increased Risk of Knee Arthroplasty at 15 Years of Follow-up : Data from the Norwegian Knee Ligament Register and the Norwegian Arthroplasty Register from 2004 to 2020
(Journal article; Peer reviewed, 2022)Background: Anterior cruciate ligament (ACL) injury is considered a risk factor for osteoarthritis. The primary aim of the present study was to investigate the cumulative risk of, and risk factors associated with, a ... -
Acoustic pharyngometry - A new method to facilitate oral appliance therapy
(Journal article; Peer reviewed, 2021)Background There is lack of reliable and accurate methods to predict treatment outcomes of oral appliance (OA) treatment. Acoustic pharyngometry (AP) is a non-invasive technique to evaluate the volume and minimal ... -
Actigraphic assessment of motor activity in acutely admitted inpatients with bipolar disorder
(Peer reviewed; Journal article, 2014-02-20)Introduction: Mania is associated with increased activity, whereas psychomotor retardation is often found in bipolar depression. Actigraphy is a promising tool for monitoring phase shifts and changes following treatment ... -
Actigraphic registration of motor activity reveals a more structured behavioural pattern in schizophrenia than in major depression
(Peer reviewed; Journal article, 2010-05-27)Background: Disturbances in motor activity pattern are seen in both schizophrenia and depression. However, this activity has rarely been studied objectively. The purpose of the present study has been to study the complexity ... -
Actigraphy as an objective intra‑individual marker of activity patterns in acute‑phase bipolar disorder: a case series
(Peer reviewed; Journal article, 2018-03-07)Background: Actigraphy could be an objective alternative to clinical ratings of motor activity in bipolar disorder (BD), which is of importance now that increased activity and energy are added as cardinal symptoms of ... -
Actigraphy assessment of motor activity and sleep in patients with alcohol withdrawal syndrome and the effects of intranasal oxytocin
(Journal article; Peer reviewed, 2020)Background and aims The alcohol withdrawal syndrome increases autonomic activation and stress in patients during detoxification, leading to alterations in motor activity and sleep irregularities. Intranasal oxytocin has ... -
Actin Post-translational Modifications: The Cinderella of Cytoskeletal Control
(Peer reviewed; Journal article, 2019)Actin is one of the most abundant proteins in eukaryotic cells and the main component of the microfilament system. It plays essential roles in numerous cellular activities including muscle contraction, maintenance of cell ... -
Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery
(Peer reviewed; Journal article, 2019)Objective: To explore monocyte and dendritic cell immune responses, and their association with future CD4+ gain in treated HIV patients with suboptimal CD4+ recovery. Design: A cross-sectional study of HIV-infected, virally ... -
Activated factor XI-antithrombin complex presenting as an independent predictor of 30-days mortality in out-of-hospital cardiac arrest patients
(Journal article; Peer reviewed, 2021)Background Cardiac arrest and cardiopulmonary resuscitation (CPR) are associated with activated coagulation and microvascular fibrin deposition with subsequent multiorgan failure and adverse outcome. Objectives Activated ... -
Activated NK cells are potent effectors against glioblastoma cells due to activating KIR2DS2 and KIR2DS4 - HLA ligand interactions - In vitro study
(Master thesis, 2013-06-03)Background: Glioblastoma (GBM) is the most malignant brain tumor, where patients' median survival is only 14,6 months after diagnosis, thus novel, effective adjuvant therapies are required. Natural Killer (NK) cells are ... -
Activation of Akt characterizes estrogen receptor positive human breast cancers which respond to anthracyclines
(Peer reviewed; Journal article, 2017-04-17)Anthracyclines are key components of human breast cancer chemotherapy. Here, we explored the role of Akt signaling in anthracycline resistance. The antitumor activity of doxorubicin and Akt inhibitor A-443654 alone or ... -
Activation of Protein Kinase A and Exchange Protein Directly Activated by cAMP Promotes Adipocyte Differentiation of Human Mesenchymal Stem Cells
(Peer reviewed; Journal article, 2012-03-27)Human mesenchymal stem cells are primary multipotent cells capable of differentiating into several cell types including adipocytes when cultured under defined in vitro conditions. In the present study we investigated the ... -
Activation-induced chromatin reorganization in neurons depends on HDAC1 activity
(Journal article; Peer reviewed, 2022)Spatial chromatin organization is crucial for transcriptional regulation and might be particularly important in neurons since they dramatically change their transcriptome in response to external stimuli. We show that ... -
The Active Tamoxifen Metabolite Endoxifen (4OHNDtam) Strongly Down-Regulates Cytokeratin 6 (CK6) in MCF-7 Breast Cancer Cells
(Peer reviewed; Journal article, 2015-04-13)Introduction: Tamoxifen is an anti-estrogen drug used in treatment of Estrogen Receptor (ER) positive breast cancer. Effects and side effects of tamoxifen is the sumof tamoxifen and all itsmetabolites. 4-Hydroxytamoxifen ...