Blar i Department of Biomedicine på emneord "VDP::Medisinske fag: 700::Basale medisinske, odontologiske og veterinærmedisinske fag: 710"
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Combining microiontophoresis and multiphoton excitation microscopy to investigate neuronal signaling
(Neuromethods, Chapter; Peer reviewed, 2019)Multiphoton excitation (MPE) microscopy allows subcellular structural and functional imaging of neurons and can be combined with techniques for activating postsynaptic receptors at spatial and temporal scales that mimic ... -
Extrasynaptic NMDA receptors on rod pathway amacrine cells: molecular composition, activation, and signaling
(Peer reviewed; Journal article, 2019)In the rod pathway of the mammalian retina, axon terminals of glutamatergic rod bipolar cells are presynaptic to AII and A17 amacrine cells in the inner plexiform layer. Recent evidence suggests that both amacrines express ... -
GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation
(Peer reviewed; Journal article, 2017-06-16)The selective and neuronal activity-dependent degradation of synaptic proteins appears to be crucial for long-term synaptic plasticity. One such protein is activity-regulated cytoskeleton-associated protein (Arc), which ... -
Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumour model
(Peer reviewed; Journal article, 2009-08)Elevated tumor interstitial fluid pressure (TIFP) is a characteristic of most solid tumors. Clinically, TIFP may hamper the uptake of chemotherapeutic drugs into the tumor tissue reducing their therapeutic efficacy. In ... -
Multiphoton excitation microscopy for the reconstructionand analysis of single neuron morphology
(Neuromethods, Chapter; Peer reviewed, 2019)Neurons are the main cellular components of the circuits of the central nervous system (CNS). The dendritic and axonal morphology of individual neurons display marked variability between neurons in different regions of the ...