Blar i Department of Biomedicine på emneord "Breast cancer"
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The effect of hyperbaric oxygen treatment on malignant progression in different breast cancer models in vivo
(Master thesis, 2016-07-01)Background: Hypoxia is an important feature of most solid tumors and has shown to serve as a mediator for aggressive tumor growth and malignant progression of cancer. A correlation between low oxygen tension in tumors and ... -
The effect of hyperbaric oxygen treatment, alone or in combination with 5-FU, on a MDA-MB-231 human mammary tumor model
(Master thesis, 2012-06-20)Background: Previous studies of hyperbaric oxygen (HBO) treatment on chemically induced and murine breast cancer models have shown promising results. This study was performed to elucidate the effects of HBO on a human ... -
The in vivo effect of integrin α11-deficiency and PDGFR inhibition in breast cancer
(Master thesis, 2018-10-19)Background: The tumor microenvironment is a major contributor to breast cancer progression. The abnormal composition of the extracellular matrix and its deregulated interactions with stromal cells, which is characterizing ... -
Neoadjuvant chemotherapy in breast cancer-response evaluation and prediction of response to treatment using dynamic contrast-enhanced and diffusion-weighted MR imaging
(Peer reviewed; Journal article, 2011)Objective To explore the predictive value of MRI parameters and tumour characteristics before neoadjuvant chemotherapy (NAC) and to compare changes in tumour size and tumour apparent diffusion coefficient (ADC) during ... -
A novel GFP nude rat model to investigate tumor-stroma interactions
(Peer reviewed; Journal article, 2014-12-21)Backgroud: A key strategy for the study of the tumor microenvironment is to implant human tumor cells in an immunodeficient rodent strain ubiquitously expressing a fluorescent marker. Here, a novel nude rat expressing a ...